Prof. Dr. PINAR ÇALIK

Yayın Ağı

Makaleler 100

1. Dual-acting single-engineered hybrid-architectured promoters enhance and convert expressions into multi-carbon source-regulated systems in Komagataella phaffii

AVCI B., ÇALIK P.

Enzyme and Microbial Technology , cilt.191, 2025 (SCI-Expanded, Scopus)

2. Biochemical production from sustainable carbon sources by Komagataella phaffii

Raja W. A., ÇALIK P.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.219, 2025 (SCI-Expanded, Scopus)

3. MachineTFBS: Motif-based method to predict transcription factor binding sites with first-best models from machine learning library

YAMAN O. U., ÇALIK P.

Biochemical Engineering Journal , cilt.198, 2023 (SCI-Expanded, Scopus)

4. Saccharomyces cerevisiae cis-acting DNA sequences curation pipeline (Sc-cADSs-CP): Master transcription factors prediction in yeasts

Yaman O. U., Avcı B., Çalık P.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.188, 2022 (SCI-Expanded, Scopus)

5. Hybrid-architectured promoter design to engineer expression in yeast

Ergun B. G., ÇALIK P.

RECOMBINANT PROTEIN EXPRESSION: EUKARYOTIC HOSTS , cilt.660, ss.81-104, 2021 (SCI-Expanded, Scopus)

6. Hybrid-architectured promoter design to deregulate expression in yeast

Ergun B. G., ÇALIK P.

RECOMBINANT PROTEIN EXPRESSION: EUKARYOTIC HOSTS , cilt.660, ss.105-125, 2021 (SCI-Expanded, Scopus)

7. Ethanol fed-batch bioreactor operation to enhance therapeutic protein production in Pichia pastoris under hybrid-architectured ADH2 promoter

Wehbe O., Yaman O. U., Çalık P.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.164, 2020 (SCI-Expanded, Scopus)

8. Hybrid-architectured double-promoter expression systems enhance and upregulate-deregulated gene expressions inPichia pastorisin methanol-free media

Demir I., ÇALIK P.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , cilt.104, sa.19, ss.8381-8397, 2020 (SCI-Expanded, Scopus)

9. Transcriptional regulatory proteins in central carbon metabolism ofPichia pastorisandSaccharomyces cerevisiae

Kalender O., ÇALIK P.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , cilt.104, sa.17, ss.7273-7311, 2020 (SCI-Expanded, Scopus)

10. Engineered Deregulation of Expression in Yeast with Designed Hybrid-Promoter Architectures in Coordination with Discovered Master Regulator Transcription Factor

Ergun B. G., Demir I., Ozdamar T. H., Gasser B., Mattanovich D., Çalık P.

ADVANCED BIOSYSTEMS , cilt.4, 2020 (SCI-Expanded, ESCI, Scopus)

11. Isolation of High-Quality RNA from Pichia pastoris

Öztürk S., Demir İ., ÇALIK P.

Current Protocols in Protein Science , cilt.98, sa.1, 2019 (Scopus)

12. Engineering of alcohol dehydrogenase 2 hybrid-promoter architectures in Pichia pastoris to enhance recombinant protein expression on ethanol

Ergun B. G., Gasser B., Mattanovich D., Calik P.

BIOTECHNOLOGY AND BIOENGINEERING , cilt.116, sa.10, ss.2674-2686, 2019 (SCI-Expanded, Scopus)

13. Established and Upcoming Yeast Expression Systems

GÜNDÜZ ERGÜN B., Huccetogullari D., Ozturk S., Celik E., ÇALIK P.

RECOMBINANT PROTEIN PRODUCTION IN YEAST , ss.1-74, 2019 (SCI-Expanded, Scopus)

14. A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii

Ata O., Rebnegger C., Tatto N. E., Valli M., Mairinger T., Hann S., et al.

NATURE COMMUNICATIONS , cilt.9, 2018 (SCI-Expanded, Scopus)

15. Hybrid fed-batch bioreactor operation design: control of substrate uptake enhances recombinant protein production in high-cell-density fermentations

ÇALIK P., Hoxha B., ÇALIK GARCİA G., Ozdamar T. H.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.93, sa.11, ss.3326-3335, 2018 (SCI-Expanded, Scopus)

16. Naturally occurring novel promoters around pyruvate branch-point for recombinant protein production in Pichia pastoris (Komagataella phaffii): Pyruvate decarboxylase- and pyruvate kinase- promoters

Massahi A., ÇALIK P.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.138, ss.111-120, 2018 (SCI-Expanded, Scopus)

17. Naturally occurring novel promoters for recombinant protein production around pyruvate branch-point in Pichia pastoris

ÇALIK P., Massahi A.

NEW BIOTECHNOLOGY , cilt.44, 2018 (SCI-Expanded, Scopus)

18. Analyses of extracellular protein production in Bacillus subtilis - II: Responses of reaction network to oxygen transfer at transcriptional level

KOCABAŞ P., ÇALIK GARCİA G., ÇALIK P., Ozdamar T. H.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.127, ss.242-261, 2017 (SCI-Expanded, Scopus)

19. Analyses of extracellular protein production in Bacillus subtilis - I: Genome-scale metabolic model reconstruction based on updated gene-enzyme-reaction data

KOCABAŞ P., ÇALIK P., ÇALIK GARCİA G., Ozdamar T. H.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.127, ss.229-241, 2017 (SCI-Expanded, Scopus)

20. Beet molasses-based feeding strategy enhances recombinant thermostable glucose isomerase production by Escherichia coli BL21 (DE3)

Yaman S., ÇALIK P.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY , cilt.64, sa.6, ss.944-954, 2017 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

21. Double promoter expression systems for recombinant protein production by industrial microorganisms

Ozturk S., Ergun B. G., ÇALIK P.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , cilt.101, sa.20, ss.7459-7475, 2017 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

22. Transcriptional engineering of the glyceraldehyde-3-phosphate dehydrogenase promoter for improved heterologous protein production in Pichia pastoris

Ata O., Prielhofer R., Gasser B., Mattanovich D., ÇALIK P.

BIOTECHNOLOGY AND BIOENGINEERING , cilt.114, sa.10, ss.2319-2327, 2017 (SCI-Expanded, Scopus)

23. Endogenous signal peptides in recombinant protein production by Pichia pastoris: From in-silico analysis to fermentation

Massahi A., ÇALIK P.

JOURNAL OF THEORETICAL BIOLOGY , cilt.408, ss.22-33, 2016 (SCI-Expanded, Scopus)

24. Parametric continuous feed stream design to fine-tune fed-batch bioreactor performance: recombinant human growth hormone production in Bacillus subtilis

ÇALIK GARCİA G., KOCABAŞ P., Afsar H., ÇALIK P., Ozdamar T. H.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.91, sa.11, ss.2740-2750, 2016 (SCI-Expanded, Scopus)

25. Oxygen transfer as a tool for fine-tuning recombinant protein production by Pichia pastoris under glyceraldehyde-3-phosphate dehydrogenase promoter

Gunes H., ÇALIK P.

BIOPROCESS AND BIOSYSTEMS ENGINEERING , cilt.39, sa.7, ss.1061-1072, 2016 (SCI-Expanded, Scopus)

26. Fed-Batch Biomolecule Production by Bacillus subtilis: A State of the Art Review

Ozturk S., ÇALIK P., Ozdamar T. H.

TRENDS IN BIOTECHNOLOGY , cilt.34, sa.4, ss.329-345, 2016 (SCI-Expanded, Scopus)

27. Methanol feeding strategy design enhances recombinant human growth hormone production by Pichia pastoris

Gunes H., BOY E., Ata O., Zerze G. H., ÇALIK P., Ozdamar T. H.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.91, sa.3, ss.664-671, 2016 (SCI-Expanded, Scopus)

28. Lignocellulose degrading extremozymes produced by Pichia pastoris: current status and future prospects

Ergun B. G., ÇALIK P.

BIOPROCESS AND BIOSYSTEMS ENGINEERING , cilt.39, sa.1, ss.1-36, 2016 (SCI-Expanded, Scopus)

29. Feeding strategy design for recombinant human growth hormone production by Bacillus subtilis

Sahin B., Ozturk S., ÇALIK P., Ozdamar T. H.

BIOPROCESS AND BIOSYSTEMS ENGINEERING , cilt.38, sa.10, ss.1855-1865, 2015 (SCI-Expanded, Scopus)

30. Recombinant protein production by sucrose-utilizing Escherichia coli W: untreated beet molasses-based feeding strategy development

Akdag B., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.90, sa.6, ss.1070-1076, 2015 (SCI-Expanded, Scopus)

31. Codon optimization of xylA gene for recombinant glucose isomerase production in Pichia pastoris and fed-batch feeding strategies to fine-tune bioreactor performance

Ata O., BOY E., Gunes H., ÇALIK P.

BIOPROCESS AND BIOSYSTEMS ENGINEERING , cilt.38, sa.5, ss.889-903, 2015 (SCI-Expanded, Scopus)

32. Recombinant protein production in Pichia pastoris under glyceraldehyde-3-phosphate dehydrogenase promoter: From carbon source metabolism to bioreactor operation parameters

ÇALIK P., Ata O., Gunes H., Massahi A., BOY E., KESKİN A., et al.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.95, ss.20-36, 2015 (SCI-Expanded, Scopus)

33. In-silico determination of Pichia pastoris signal peptides for extracellular recombinant protein production

Massahi A., ÇALIK P.

JOURNAL OF THEORETICAL BIOLOGY , cilt.364, ss.179-188, 2015 (SCI-Expanded, Scopus)

34. Metabolic reaction network of Pichia pastoris with glycosylation reactions: Flux analysis for erythropoietin production

Eskitoros M. S., Ata O., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.89, sa.11, ss.1675-1685, 2014 (SCI-Expanded, Scopus)

35. Co-substrate mannitol feeding strategy design in semi-batch production of recombinant human erythropoietin production by Pichia pastoris

Eskitoros M. S., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.89, sa.5, ss.644-651, 2014 (SCI-Expanded, Scopus)

36. Effect of co-substrate sorbitol different feeding strategies on human growth hormone production by recombinant Pichia pastoris

ÇALIK P., Bozkurt B., Zerze G. H., Inankur B., Bayraktar E., BOY E., et al.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.88, sa.9, ss.1631-1640, 2013 (SCI-Expanded, Scopus)

37. Beet molasses based exponential feeding strategy for thermostable glucose isomerase production by recombinant Escherichia coli BL21 (DE3)

Angardi V., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.88, sa.5, ss.845-852, 2013 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

38. Recombinant transglutaminase production by metabolically engineered pichia pastoris

Gunduz B., Yilmaz R., ÇALIK P.

NEW BIOTECHNOLOGY , cilt.29, 2012 (SCI-Expanded, Scopus)

39. Strategy development for therapeutic protein production by Pichia pastoris: human growth hormone

Bozkurt B., ÇALIK P.

NEW BIOTECHNOLOGY , cilt.29, 2012 (SCI-Expanded, Scopus)

40. Production of recombinant proteins by yeast cells

Celik E., ÇALIK P.

BIOTECHNOLOGY ADVANCES , cilt.30, sa.5, ss.1108-1118, 2012 (SCI-Expanded, Scopus)

41. A rapid method for detection of genetically modified organisms based on magnetic separation and surface-enhanced Raman scattering

GÜVEN B., BOYACI İ. H., TAMER U., ÇALIK P.

ANALYST , cilt.137, sa.1, ss.202-208, 2012 (SCI-Expanded, Scopus)

42. Enhanced recombinant human erythropoietin production by Pichia pastoris in methanol fed-batch/sorbitol batch fermentation through pH optimization

Soyaslan E. S., ÇALIK P.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.55, sa.1, ss.59-65, 2011 (SCI-Expanded, Scopus)

43. Dynamic flux balance analysis for pharmaceutical protein production by Pichia pastoris: Human growth hormone

ÇALIK P., Sahin M., Taspinar H., Soyaslan E. S., Inankur B.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.48, sa.3, ss.209-216, 2011 (SCI-Expanded, Scopus)

44. Influence of pH on recombinant human growth hormone production by Pichia pastoris

ÇALIK P., Bayraktar E., Inankur B., Soyaslan E. S., Sahin M., Taspinar H., et al.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.85, sa.12, ss.1628-1635, 2010 (SCI-Expanded, Scopus)

45. Metabolic Flux Analysis for Recombinant Protein Production by Pichia pastoris Using Dual Carbon Sources: Effects of Methanol Feeding Rate

Celik E., ÇALIK P., Oliver S. G.

BIOTECHNOLOGY AND BIOENGINEERING , cilt.105, sa.2, ss.317-329, 2010 (SCI-Expanded, Scopus)

46. Fermentation and oxygen transfer characteristics in recombinant human growth hormone production by Pichia pastoris in sorbitol batch and methanol fed-batch operation

ÇALIK P., Inankur B., Soyaslan E. S., Sahin M., Taspinar H., Acik E., et al.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.85, sa.2, ss.226-233, 2010 (SCI-Expanded, Scopus)

47. Human growth hormone-specific aptamer identification using improved oligonucleotide ligand evolution method

ÇALIK P., Balci O., Ozdamar T. H.

PROTEIN EXPRESSION AND PURIFICATION , cilt.69, sa.1, ss.21-28, 2010 (SCI-Expanded, Scopus)

48. Bioreaction network flux analysis for human protein producing Bacillus subtilis based on genome-scale model

ÖZDAMAR H. T., Senturk B., YILMAZ O., KOCABAŞ P., Calik G., ÇALIK P.

CHEMICAL ENGINEERING SCIENCE , cilt.65, sa.1, ss.574-580, 2010 (SCI-Expanded, Scopus)

49. A structured kinetic model for recombinant protein production by Mut(+) strain of Pichia pastoris

Celik E., ÇALIK P., Oliver S. G.

CHEMICAL ENGINEERING SCIENCE , cilt.64, sa.23, ss.5028-5035, 2009 (SCI-Expanded, Scopus)

50. Effects of pretreated beet molasses on benzaldehyde lyase production by recombinant Escherichia coli BL21(DE3)pLySs

ÇALIK P., Levent H.

JOURNAL OF APPLIED MICROBIOLOGY , cilt.107, sa.5, ss.1536-1541, 2009 (SCI-Expanded, Scopus)

51. Effects of pulse feeding of beet molasses on recombinant benzaldehyde lyase production by Escherichia coli BL21(DE3)

ÇALIK P., Levent H.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , cilt.85, sa.1, ss.65-73, 2009 (SCI-Expanded, Scopus)

52. Biotech in Turkey

GEÇKİL H., ÇALIK P.

Biotechnology Journal , cilt.4, sa.7, ss.951, 2009 (SCI-Expanded, Scopus)

53. Microarray studies in Bacillus subtilis

Kocabaş P., ÇALIK P., Çalik G., Özdamar T. H.

Biotechnology Journal , cilt.4, sa.7, ss.1012-1027, 2009 (SCI-Expanded, Scopus)

54. Regulatory effects of oxygen transfer on overexpression of recombinant benzaldehyde lyase production by Escherichia coli BL21 (DE3)

Kaya-Çeliker H., Angardi V., ÇALIK P.

Biotechnology Journal , cilt.4, sa.7, ss.1066-1076, 2009 (SCI-Expanded, Scopus)

55. Recombinant protein production by Mut(+) strain of Pichia pastoris using dual carbon sources: methanol and sorbitol

ÇALIK P., ÖNAL ÇELİK E., Oliver S. G.

NEW BIOTECHNOLOGY , cilt.25, 2009 (SCI-Expanded, Scopus)

56. Effects of methanol plus sorbitol on recombinant human growth hormone production by Pichia pastoris Mut

Bayraktar E., ÇALIK P., Yilmaz R., Ozdamar T.

NEW BIOTECHNOLOGY , cilt.25, 2009 (SCI-Expanded, Scopus)

57. Fed-batch methanol feeding strategy for recombinant protein production by Pichia pastoris in the presence of co-substrate sorbitol

Celik E., ÇALIK P., Oliver S. G.

YEAST , cilt.26, sa.9, ss.473-484, 2009 (SCI-Expanded, Scopus)

58. Effects of carbon sources and feeding strategies on human growth hormone production by metabolically engineered Pichia pastoris

Acik E., ÇALIK P., Ozdamar T.

NEW BIOTECHNOLOGY , cilt.25, 2009 (SCI-Expanded, Scopus)

59. The influence of carbon sources on recombinant-human-growth-hormone production by Pichia pastoris is dependent on phenotype: a comparison of Mut(s) and Mut(+) strains

Orman M. A., ÇALIK P., Ozdamar T. H.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY , cilt.52, ss.245-255, 2009 (SCI-Expanded, Scopus)

60. Glucose isomerase production on a xylan-based medium by Bacillus thermoantarcticus

ÇALIK P., Angardi V., Haykir N. I., BOYACI İ. H.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.43, sa.1, ss.8-15, 2009 (SCI-Expanded, Scopus)

61. Expression System for Recombinant Human Growth Hormone Production from Bacillus subtilis

ÖZDAMAR H. T., Sentuerk B., Yilmaz O. D., Calik G., Celik E., ÇALIK P.

BIOTECHNOLOGY PROGRESS , cilt.25, sa.1, ss.75-84, 2009 (SCI-Expanded, Scopus)

62. Development of enhanced ultrafiltration methodologies for the resolution of racemic benzoin

Olceroglu A. H., ÇALIK P., YILMAZ L.

JOURNAL OF MEMBRANE SCIENCE , cilt.322, sa.2, ss.446-452, 2008 (SCI-Expanded, Scopus)

63. Use of biodiesel byproduct crude glycerol as the carbon source for fermentation processes by recombinant Pichia pastoris

Celik E., Ozbay N., OKTAR N., ÇALIK P.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH , cilt.47, sa.9, ss.2985-2990, 2008 (SCI-Expanded, Scopus)

64. Expression system for synthesis and purification of recombinant human growth hormone in Pichia pastoris and structural analysis by MALDI-ToF mass spectrometry

ÇALIK P., Orman M. A., Celik E., Halloran S. M., Calik G., Ozdamar T. H.

BIOTECHNOLOGY PROGRESS , cilt.24, sa.1, ss.221-226, 2008 (SCI-Expanded, Scopus)

65. Production of recombinant human erythropoietin from Pichia pastoris and its structural analysis

Celik E., Calik P., Halloran S. M., Oliver S. G.

JOURNAL OF APPLIED MICROBIOLOGY , cilt.103, sa.6, ss.2084-2094, 2007 (SCI-Expanded, Scopus)

66. PH influences intracellular reaction network of beta-lactamase producing Bacillus licheniformis

Calik P., Ileri N.

CHEMICAL ENGINEERING SCIENCE , cilt.62, ss.5206-5211, 2007 (SCI-Expanded, Scopus)

67. Phosphate enrichment and fed-batch operation for prolonged beta-lactamase production by Bacillus licheniformis

Ileri N., Calik P., Sengul A.

JOURNAL OF APPLIED MICROBIOLOGY , cilt.102, sa.5, ss.1418-1426, 2007 (SCI-Expanded, Scopus)

68. Chiral separation of racemic benzoin via enzyme enhanced ultrafiltration

Olceroglu A. H., Calik P., Yilmaz L.

DESALINATION , cilt.200, ss.464-465, 2006 (SCI-Expanded, Scopus)

69. Fermentation characteristics of L-tryptophan production by thermoacidophilic Bacillus acidocaldarius in a defined medium

Kocabas P., Calik P., Ozdamar T. H.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.39, sa.5, ss.1077-1088, 2006 (SCI-Expanded, Scopus)

70. Influence of controlled-pH and uncontrolled-pH operations on recombinant benzaldehyde lyase production by Escherichia coli

Calik P., Yilgor P., Demir A.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.38, sa.5, ss.617-627, 2006 (SCI-Expanded, Scopus)

71. Effects of pH strategy on endo- and exo-metabolome profiles and sodium potassium hydrogen ports of beta-lactamase-producing Bacillus licheniformis

Ileri N., Calik P.

BIOTECHNOLOGY PROGRESS , cilt.22, sa.2, ss.411-419, 2006 (SCI-Expanded, Scopus)

72. Effects of spray drying temperature and additives on the stability of serine alkaline protease powders

Namaldi A., Calik P., Uludag Y.

DRYING TECHNOLOGY , cilt.24, sa.11, ss.1495-1500, 2006 (SCI-Expanded, Scopus)

73. Novel antifoam for fermentation processes: Fluorocarbon-hydrocarbon hybrid unsymmetrical bolaform surfactant

Calik P., Ileri N., Erdinc B., Aydogan N., Argun M.

LANGMUIR , cilt.21, sa.19, ss.8613-8619, 2005 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

74. Oxygen transfer effects in beta-lactamase fermentation by Bacillus licheniformis in a glucose-based defined medium

Calik P., Arifoglu M., Calik G.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.80, sa.9, ss.1062-1071, 2005 (SCI-Expanded, Scopus)

75. Oxygen transfer effects on recombinant benzaldehyde lyase production

Calik P., Yilgor P., Ayhan P., Demir A.

CHEMICAL ENGINEERING SCIENCE , cilt.59, ss.5075-5083, 2004 (SCI-Expanded, Scopus)

76. Fermentation and oxygen transfer characteristics in serine alkaline protease production by recombinant Bacillus subtilis in molasses-based complex medium

Calik G., Pehlivan N., Ozcelik I., Calik P., Ozdamar T.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.79, sa.11, ss.1243-1250, 2004 (SCI-Expanded, Scopus)

77. Metabolic engineering of aromatic group amino acid pathway in Bacillus subtilis for L-phenylalanine production

Ozcelik I., Calik P., Calik G., Ozdamar T.

CHEMICAL ENGINEERING SCIENCE , cilt.59, ss.5019-5026, 2004 (SCI-Expanded, Scopus)

78. Bioprocess parameters and oxygen transfer characteristics in beta-lactamase production by Bacillus species

Celik E., Calik P.

BIOTECHNOLOGY PROGRESS , cilt.20, sa.2, ss.491-499, 2004 (SCI-Expanded, Scopus)

79. Inorganic compounds have dual effect on recombinant protein production: influence of anions and cations on serine alkaline protease production

Calik P., Bilir E., Ozcelik I., Calik G., Ozdamar T.

JOURNAL OF APPLIED MICROBIOLOGY , cilt.96, sa.1, ss.194-200, 2004 (SCI-Expanded, Scopus)

80. Protein-based complex medium design for recombinant serine alkaline protease production

Calik P., Celik E., Telli I., Oktar C., Ozdemir E.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.33, sa.7, ss.975-986, 2003 (SCI-Expanded, Scopus)

81. Overexpression of serine alkaline protease encoding gene in Bacillus species: performance analyses

Calik P., Kalender N., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.33, sa.7, ss.967-974, 2003 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

82. Overexpression of a serine alkaline protease gene in Bacillus licheniformis and its impact on the metabolic reaction network

Calik P., Tomlin G., Oliver S., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.32, sa.6, ss.706-720, 2003 (SCI-Expanded, Scopus)

83. Utilization of pretreated molasses for serine alkaline protease production with recombinant Bacillus species

Calik G., Pehlivan N., Kalender N., Ozdamar T., Calik P.

CHEMICAL ENGINEERING COMMUNICATIONS , cilt.190, ss.630-644, 2003 (SCI-Expanded, Scopus)

84. Regulatory effects of alanine-group amino acids on serine alkaline protease production by recombinant Bacillus licheniformis

ÇALIK P., Bayram A., Ozdamar T.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY , cilt.37, ss.165-171, 2003 (SCI-Expanded, Scopus)

85. Bioreactor operation parameters as tools for metabolic regulations in fermentation processes: influence of pH conditions

Calik P., Bilir E., Calik G., Ozdamar T.

CHEMICAL ENGINEERING SCIENCE , cilt.58, ss.759-766, 2003 (SCI-Expanded, Scopus)

86. Enzyme-ion exchanger interactions in serine alkaline protease separation: theory, equilibria and kinetics

Calik P., Ozcelik I., Calik G., Ozdamar T.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.12, sa.3, ss.193-204, 2002 (SCI-Expanded, Scopus)

87. Influence of pH conditions on metabolic regulations in serine alkaline protease production by Bacillus licheniformis

Calik P., Bilir E., Calik G., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.31, sa.5, ss.685-697, 2002 (SCI-Expanded, Scopus)

88. Metabolic flux analysis for human therapeutic protein productions and hypothesis for new therapeutical strategies in medicine

Calik P., Ozdamar T.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.11, sa.1, ss.49-68, 2002 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

89. Bioreaction network flux analysis for industrial microorganisms: A review

Calik P., Ozdamar T.

REVIEWS IN CHEMICAL ENGINEERING , cilt.18, sa.6, ss.553-596, 2002 (SCI-Expanded, Scopus)

90. Carbon sources affect metabolic capacities of Bacillus species for the production of industrial enzymes: theoretical analyses for serine and neutral proteases and alpha-amylase

Calik P., Ozdamar T.

BIOCHEMICAL ENGINEERING JOURNAL , cilt.8, sa.1, ss.61-81, 2001 (SCI-Expanded, Scopus)

91. Bioprocess development for serine alkaline protease production: A review

Calik P., Calik G., Ozdamar T.

REVIEWS IN CHEMICAL ENGINEERING , cilt.17, ss.1-62, 2001 (SCI-Expanded, Scopus)

92. Metabolic flux analyses for serine alkaline protease production

ÇALIK P., ÇALIK P., Takac S., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.27, sa.10, ss.793-805, 2000 (SCI-Expanded, Scopus)

93. Oxygen-transfer strategy and its regulation effects in serine alkaline protease production by Bacillus licheniformis

Calik P., Calik G., Ozdamar T.

BIOTECHNOLOGY AND BIOENGINEERING , cilt.69, sa.3, ss.301-311, 2000 (SCI-Expanded, Scopus)

94. Mass flux balance-based model and metabolic flux analysis for collagen synthesis in the fibrogenesis process of human liver

ÇALIK P., Akbay A.

MEDICAL HYPOTHESES , cilt.55, sa.1, ss.5-14, 2000 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

95. Separation of the protease enzymes of Bacillus licheniformis from the fermentation medium by crossflow ultrafiltration

Takac S., Elmas S., ÇALIK P., Ozdamar T.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY , cilt.75, sa.6, ss.491-499, 2000 (SCI-Expanded, Scopus)

96. Serine alkaline protease overproduction capacity of Bacillus licheniformis

ÇALIK P., Takac S., ÇALIK P., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.26, sa.1, ss.45-60, 2000 (SCI-Expanded, Scopus)

97. Metabolic flux analysis for serine alkaline protease fermentation by Bacillus licheniformis in a defined medium: Effects of the oxygen transfer rate

Calik P., Calik G., Takac S., Ozdamar T.

BIOTECHNOLOGY AND BIOENGINEERING , cilt.64, sa.2, ss.151-167, 1999 (SCI-Expanded, Scopus)

98. Mass flux balance-based model and metabolic pathway engineering analysis for serine alkaline protease synthesis by Bacillus licheniformis

Çalık P., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.24, sa.10, ss.621-635, 1999 (SCI-Expanded, Scopus)

99. Growth and kappa-carrageenan immobilization of Pseudomonas dacunhae cells for L-alanine production

Calik G., Savasci H., Calik P., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.24, sa.1-2, ss.67-74, 1999 (SCI-Expanded, Scopus)

100. Oxygen transfer effects in serine alkaline protease fermentation by Bacillus licheniformis: Use of citric acid as the carbon source

Calik P., Calik G., Ozdamar T.

ENZYME AND MICROBIAL TECHNOLOGY , cilt.23, sa.7-8, ss.451-461, 1998 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 21

1. Rekombinant Protein Üretimi

ÇALIK P.

TAGEM GIDA ARAŞTIRMALARIPROGRAM DEĞERLENDİRME TOPLANTISI, Antalya, Türkiye, 20 - 24 Şubat 2017

2. The Effect of Cell Cycle Synchronization on Recombinant Protein Production by Pichia pastoris

Hüccetoğulları D., ÇALIK P.

Pichia 2016 Conference, 3 Nisan - 06 Haziran 2016

3. Effect of oxygen transfer conditions on recombinant protein production by Pichia pastoris under glyceraldehyde 3 phosphate dehydrogenase promoter

GÜNEŞ H., ÇALIK P.

Pichia 2016 Conference, 3 - 06 Nisan 2016

Kitaplar 3

Metrikler

Yayın

125

Yayın (WoS)

114

Yayın (Scopus)

100

Atıf (WoS)

2205

H-İndeks (WoS)

Atıf (Scopus)

2456

H-İndeks (Scopus)

Atıf (Scholar)

3635

H-İndeks (Scholar)

Atıf (Sobiad)

H-İndeks (Sobiad)

Proje

Fikri Mülkiyet

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler

Yayın

Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

H-İndeks (WoS)

Atıf (Scopus)

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Atıf (Sobiad)

H-İndeks (Sobiad)

Proje

Fikri Mülkiyet

Tez Danışmanlığı

Açık Erişim