Methanol feeding strategy design enhances recombinant human growth hormone production by Pichia pastoris


Gunes H., BOY E. , Ata O., Zerze G. H. , ÇALIK P. , Ozdamar T. H.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol.91, no.3, pp.664-671, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 91 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1002/jctb.4619
  • Title of Journal : JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
  • Page Numbers: pp.664-671

Abstract

BACKGROUND: The effects of designed methanol and co-substrate feeding strategies on fed-batch recombinant human growth hormone (rhGH) production by Pichia pastoris hGH-Mut(+) were investigated.