Metabolic reaction network of Pichia pastoris with glycosylation reactions: Flux analysis for erythropoietin production


Eskitoros M. S., Ata O., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol.89, no.11, pp.1675-1685, 2014 (SCI-Expanded) identifier identifier

Abstract

BACKGROUND: Biochemical reaction network of Pichia pastoris was improved by including N-glycosylation pathway reactions to determine the intracellular reaction rates for glycosylated protein production.