Metabolic reaction network of Pichia pastoris with glycosylation reactions: Flux analysis for erythropoietin production

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Copy For Citation

Eskitoros M. S., Ata O., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol.89, no.11, pp.1675-1685, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 89 Issue: 11
• Publication Date: 2014
• Doi Number: 10.1002/jctb.4242
• Journal Name: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1675-1685
• Middle East Technical University Affiliated: Yes

Abstract

BACKGROUND: Biochemical reaction network of Pichia pastoris was improved by including N-glycosylation pathway reactions to determine the intracellular reaction rates for glycosylated protein production.