Metabolic reaction network of Pichia pastoris with glycosylation reactions: Flux analysis for erythropoietin production

Eskitoros M. S., Ata O., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, cilt.89, sa.11, ss.1675-1685, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 89 Sayı: 11
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1002/jctb.4242
  • Dergi Adı: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1675-1685
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

BACKGROUND: Biochemical reaction network of Pichia pastoris was improved by including N-glycosylation pathway reactions to determine the intracellular reaction rates for glycosylated protein production.