Metabolic reaction network of Pichia pastoris with glycosylation reactions: Flux analysis for erythropoietin production

Eskitoros, Melda; Ata, Ozge; ÇALIK, PINAR

doi:10.1002/jctb.4242

Metabolic reaction network of Pichia pastoris with glycosylation reactions: Flux analysis for erythropoietin production

Atıf İçin Kopyala

Eskitoros M. S. , Ata O., ÇALIK P.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, cilt.89, sa.11, ss.1675-1685, 2014 (SCI İndekslerine Giren Dergi)

Cilt numarası: 89 Konu: 11
Basım Tarihi: 2014
Doi Numarası: 10.1002/jctb.4242
Dergi Adı: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
Sayfa Sayıları: ss.1675-1685

Özet

BACKGROUND: Biochemical reaction network of Pichia pastoris was improved by including N-glycosylation pathway reactions to determine the intracellular reaction rates for glycosylated protein production.