Prof. ORHAN ADALI

Academic Titles

1999 - Continues Professor

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
1994 - 1999 Associate Professor

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
1992 - 1994 Assistant Professor

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
1989 - 1992 Lecturer

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
1980 - 1989 Research Assistant

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology

Managerial Experience

2017 - Continues Rectorate Commissioner

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
2018 - 2019 Department Academic Incentive Evaluation Commission Chairperson

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
2014 - 2019 Head of Department

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology

Non Academic Experience

1999 - Continues ÖĞRETİM ÜYESİ PROF.DR.

ORTA DOĞU TEKNİK ÜNİVERSİTESİ

Courses

Undergraduate Biochemistry Laboratory

Advising Theses

Association of the vitamin d metabolizing cyp24a1, cyp27a1, cyp27b1 and vitamin d receptor genetic polymorphisms with multiple sclerosis risk in turkish population

Adali O. (Advisor)

G.BULUT(Student), Doctorate, 2023
Analyzing the expression patterns of vitamin D metabolizing CYP27B1 and CYP24A1 in brain tissue of vitamin D treated mice with multiple sclerosis (MS)

ADALI O. (Advisor)

D.ÖZDOĞAN(Student), Postgraduate, 2022
Investigation of glutathione S-transferase (GST) expression and activity in mouse with multiple sclerosis (MS)

ADALI O. (Advisor)

D.ARÇAK(Student), Postgraduate, 2022
INVESTIGATION OF EFFECTS OF VITAMIN D AND VITAMIN D METABOLIZING CYP450 ISOZYMES ON MULTIPLE SCLEROSIS PATHOPHYSIOLOGY IN ANIMAL MODEL BY MOLECULAR APPROACHES

Adalı O. (Advisor)

E.EVİN(Student), Doctorate, 2021
Effects of Medicinal Plant Sanguisorba Minor Subsp. Balearica on Selected CYP450 Isozymes and Proinflammatory Cytokines Activity in Inflammation Induced Rat Model: An Immunochemical Approach

Adalı O.

A.İNAN(Student), Doctorate, 2021
Behavioral and molecular impact of a stress factor, acaricide perizin on honey bees (apis mellifera) of Turkey

ADALI O. (Advisor)

O.Can(Student), Doctorate, 2020
Association analysis of cholesterol 7- alpha hydroxylase (CYP7A1) and cholesterol 24-hydroxlase (CYP46A1) genetic polymorphisms and multiple sclerosis risk in turkish population

Adalı O.

E.SEZER(Student), Postgraduate, 2019
Investigation of the effects of plant phenolic oleuropein on expression levels of xenobiotic metabolizing enzymes along with potential cytotoxic and genotoxic impact on human colon cancer cell line HT-29

Adalı O. (Advisor)

E.DURMUŞ(Student), Postgraduate, 2018
Effects of resveratrol and quercetin on vitamin d metabolizing cytochrome p450 enzymes

ADALI O. (Advisor)

M.AKKULAK(Student), Postgraduate, 2016
The effects of plant originated bioactive compounds on melanogenesis and tyrosinase

ADALI O. (Co-Advisor), ÇORUH N. (Co-Advisor)

Ş.ŞAHİN(Student), Doctorate, 2016
Research of phytochemical AMPK activators against obesity and development of dietary supplements

ÇORUH N. (Co-Advisor), ADALI O. (Co-Advisor)

Y.KÜMBET(Student), Doctorate, 2016
Investigation of the effects of combine use of cisplatin and metformin on proliferation of prostate cancer cell lines and GSTP, CYP17A1 and hexokinase II enzymes

ADALI O. (Advisor)

Ö.DURUKAN(Student), Postgraduate, 2016
Effects of the plant phenolic quercetin on protein and mRNA expressions of xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line sw620

ADALI O. (Advisor)

M.ÜLGER(Student), Postgraduate, 2015
Genetic polymorphism of vitamin D3 metabolising cytochrome p450 (CYPS) enyzmes and risk of ischemic stroke in turkish population

ADALI O. (Advisor)

T.ÖNER(Student), Postgraduate, 2015
Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620

ADALI O. (Advisor)

M.Ülger(Student), Postgraduate, 2015
The effects of folk medicinal plants Viscum album L. and Epilobium hirsutum L. on protein and mrna expressions of rat liver bile acid synthesizing CYPs

ADALI O. (Advisor)

T.ÇULCU(Student), Doctorate, 2015
Investigation of plant derived substances that promote the biosynthesis of collagen; development of cosmetic and dermatological skin care products

ÇORUH N. (Co-Advisor), ADALI O. (Co-Advisor)

A.KURT(Student), Doctorate, 2015
Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and carcinogen metabolism

ADALI O. (Advisor)

E.EVİN(Student), Postgraduate, 2014
Association analysis of glutathione S-transferase omega 1 and omega 2 genetic polymorphisms and ischemic stroke risk in Turkish population

ADALI O. (Advisor)

E.BİLGİN(Student), Postgraduate, 2014
Investigation of the effects of folk medicinal plant Epilobium hirsutum L. on cytochrome P450 dependent and antioxidant enzymes: A molecular approach

ADALI O. (Advisor)

S.KARAKURT(Student), Doctorate, 2013
Analysis of immunoreactivity of nos isoforms(nNOS, eNOS, iNOS) in hippocampus of young rats classified as good and poor learners.

ADALI O. (Advisor)

E.KEÇECİOĞLU(Student), Postgraduate, 2012
Association between gamma aminobutyric acid (GABA) type B receptor gene polymorphisms and idiopathic generalized epilepsy

ADALI O. (Advisor)

E.EROĞLU(Student), Postgraduate, 2012
In vivo effect of Epilobium hirsutum L. and Viscum album L. on protein and mRNA expressions of rat liver vitamin D3 metabolizing CYP24A1 and CYP27B1 enzymes

ADALI O. (Advisor)

M.SEVER(Student), Postgraduate, 2012
Study on the molecular basis of individual variation in spatial memory in rats

ADALI O. (Advisor)

Ç.GÖKÇEK(Student), Doctorate, 2012
Effect of medicinal plants Epilobium hirsutum L. and Viscum album L. on rat liver flavin-containing monooxygenase activity and expression

ADALI O. (Advisor)

H.UFUK(Student), Postgraduate, 2012
In Vivo effect of Epilobium Hirsutum L. and Viscum Album L. on protein and mRNA expressions of rat liver vitamin D₃ metabolizing CYP24A1 and CYP27B1 enzymes

ADALI O. (Advisor)

M.Sever(Student), Postgraduate, 2012
Association of the CYP2E1, FMO3, NQO1, GST and NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population

ADALI O. (Advisor)

A.ÖZÇELİK(Student), Doctorate, 2011
Analysis of cytochrome P4501A1 genetic polymorphisms in patients with ischemic stroke

ADALI O. (Advisor)

A.ÇINAR(Student), Postgraduate, 2011
Polymorphisms of epoxide hydrolase genes and ischemic stroke risk in Turkish population

ADALI O. (Advisor)

Y.MİÇOOĞULLARI(Student), Postgraduate, 2011
Association between gamma aminobutyric acid (GABA) type B receptors gene polymorphisms and idiopathic generalized epilepsy

ADALI O. (Advisor)

E.Eroğlu(Student), Postgraduate, 2011
Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in Turkish children

ADALI O. (Advisor)

G.ULUSOY(Student), Doctorate, 2009
Pharmacogenetics of childhood acute lymphoblastic leukemia: Investigation of frequency of TPMT risk alleles for thiopurine toxicity and the role of SULT1A1, EPHX1 polymorphisms as risk factors for development of the disease

ADALI O. (Advisor)

T.TÜMER(Student), Doctorate, 2009
Apolipoprotein A5 genetic polymorphisms in Turkish population and the risk of ischemic stroke

ADALI O. (Advisor)

E.ŞAHİN(Student), Postgraduate, 2008
Effects of benzene on liver, kidney and lung CYP1A, CYP2B4, CYP2E1 and CYP3A6 mRNA, protein level, and drug metabolizing enzyme activities and toxicity in diabetic rabbits

ADALI O. (Advisor)

Ş.ARSLAN(Student), Doctorate, 2008
The effects of phenolic compound tannic acid on phase II and cytochrome p450 dependent enzymes in rabbit liver and kidney

ADALI O. (Advisor)

S.KARAKURT(Student), Postgraduate, 2008
Investigation of the association between genetic and activity polymorphisms of paraoxonase 1 and ischemic stroke risk

ADALI O. (Advisor)

B.CAN(Student), Doctorate, 2007
Human serum arylesterase and glutathione S-transferase activities in patients with ischemic stroke compared to healthy controls

ADALI O. (Advisor)

A.TÜRKANOĞLU(Student), Postgraduate, 2007
Understanding city as an architectural and non-architectural program: learning from Ankara

ADALI O. (Advisor)

Ö.Mutlu(Student), Postgraduate, 2006
Mathematical analysis of peeling of carrots

ADALI O. (Advisor)

Ö.Aydın(Student), Postgraduate, 2005
New monumentality

ADALI O. (Advisor)

Ü.Özten(Student), Postgraduate, 2005
A critical evaluation of governance in the framework of rural development in Turkey

ADALI O. (Advisor)

P.Kovancı(Student), Doctorate, 2005
An inquiry on the limits of multidisciplinary collaboration in design :architectural competition

ADALI O. (Advisor)

G.Erdem(Student), Postgraduate, 2005
Essential facilities doctrine under ec competition law and particular implications of the doctrine for telecommunications sectors in Eu and Turkey

ADALI O. (Advisor)

M.Bilal(Student), Postgraduate, 2004
Phase control by injection locking

ADALI O. (Advisor)

G.Şener(Student), Postgraduate, 2004
Utilization of natural gas, optimization of cogeneration/combined cycle applications in campus environment

ADALI O. (Advisor)

E.Özgirgin(Student), Postgraduate, 2004
Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population

ADALI O. (Advisor)

G.ULUSOY(Student), Postgraduate, 2004
Developing alternative modes of tourism in Turkey

ADALI O. (Advisor)

B.Tezcan(Student), Postgraduate, 2004
Characterization and modulation by drugs and other effectors of bovine liver microsomal flavin monooxygenase (FMO)

ADALI O. (Advisor)

D.FULYA(Student), Postgraduate, 2004
Discourses of Kemalism and Islamism on the political dimension of EU - Turkey Relations

ADALI O. (Advisor)

D.Fulya(Student), Postgraduate, 2004
Oxidation off acid red 151 solutions by peroxone(o3/h2o2) process

ADALI O. (Advisor)

E.Acar(Student), Postgraduate, 2004
Cytochrome P450 dependent drug metabolism in diabetic rabbits

ADALI O. (Advisor)

Ş.ARSLAN(Student), Postgraduate, 2003
Sheep liver microsomal flavin-monooxygenases: Characterization and effect of some modulators

ADALI O. (Advisor)

B.CAN(Student), Postgraduate, 2002
Characterization and comparison of sheep and bovine liver beta-galactosidase

ADALI O. (Advisor)

A.ERCAN(Student), Postgraduate, 2001
Characterization and comparison of sheep and bovine liver b-galactosidase

ADALI O. (Advisor)

A.Ercan(Student), Postgraduate, 2001
Studies on carnivores of Düzlerçamı game reserve, Antalya

BİLGİN C. C. (Co-Advisor), ADALI O. (Co-Advisor)

A.CEREN(Student), Postgraduate, 1999
Comparison of different methods of beta-galactosidase immobilization on/in poly (2-hydroxyethyl methacrylate) supports.

ADALI O. (Advisor)

E.Türker(Student), Postgraduate, 1996
Effects of pyridine on rabbit liver, kidney and lung microsomal cytochrome P450 dependent drug metabolizing enzymes

ADALI O. (Advisor)

A.MİNE(Student), Postgraduate, 1995
Immunochemical and sub-cultural characterization of sheep lung cytochrome P450LgM2

ADALI O. (Advisor)

T.Mohamed(Student), Postgraduate, 1993
Immunochemical and sub-structural characterization of sheep lung cytochrome P450LgM2

ADALI O. (Advisor)

T.MOHAMMED(Student), Postgraduate, 1993

Academic and Administrative Experience

1999 - Continues Professor

1994 - 1999 Associate Professor

1992 - 1994 Assistant Professor

1989 - 1992 Lecturer

1980 - 1989 Research Assistant

2017 - Continues Rectorate Commissioner

2018 - 2019 Department Academic Incentive Evaluation Commission Chairperson

2014 - 2019 Head of Department

1999 - Continues ÖĞRETİM ÜYESİ PROF.DR.

Undergraduate Biochemistry Laboratory