Prof. Dr. MAYDA GÜRSEL

Metrikler

Yayın

Atıf (WoS)

6182

H-İndeks (WoS)

Atıf (Scopus)

4624

H-İndeks (Scopus)

Atıf (Scholar)

235

H-İndeks (Scholar)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Eğitim Bilgileri

1993 - 1995

Doktora

University of London-The School of Pharmacy, Immunoloji, Birleşik Krallık

Araştırma Alanları

Sağlık Bilimleri

Akademik Unvanlar / Görevler

2016 - Devam Ediyor

Prof. Dr.

Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Biyolojik Bilimler Bölümü

2006 - Devam Ediyor

Doç. Dr.

Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Moleküler Biyoloji Ve Genetik Bölümü

Yönetilen Tezler

2020

Doktora

Leishmania RNA virus ile enfekte Leishmania major eksozomlarının karakterizasyonu ve L. Major enfeksyonunda sitosolik DNA algılama ile alakalı yolakların etkisinin değerlendirilmesi

GÜRSEL M. (Danışman)

İ.Cem(Öğrenci)

2019

Doktora

Kinetoplast DNAnın Leishmania major deneysel enfeksiyonu üzerine etkisi ve kütanöz Leishmaniasise karşı Leishmania hücre dışı keseciklerine dayalı aşının BALB/C farelerde değerlendirilmesi

GÜRSEL M. (Danışman)

İ.Cihan(Öğrenci)

2019

Yüksek Lisans

Doğal bağışıklık hücrelerinde intravenöz immünglobulin-aracılı fonksiyonel değişimlerin karakterizasyonu.

GÜRSEL M. (Danışman)

B.Geçkin(Öğrenci)

2018

Yüksek Lisans

Characterization of STING mediated innate immune sensing in the context of pathology

GÜRSEL M. (Danışman)

H.ASENA(Öğrenci)

2018

Doktora

Immune modulatory effects of pediococcus pentosaceus derived membrane vesicles: Mechanism of action and therapeutic applications

GÜRSEL M. (Danışman)

E.ALPDÜNDAR(Öğrenci)

2017

Yüksek Lisans

Effect of immunosuppressive oligodeoxynucleotide A151 on inflammasome activation pathways

GÜRSEL M. (Danışman)

N.SÜRÜCÜ(Öğrenci)

2017

Yüksek Lisans

Immunomodulatory activities of RNA species derived from commensal and pathogenic bacteria

GÜRSEL M. (Danışman)

B.KAYAOĞLU(Öğrenci)

2017

Doktora

Vaccine adjuvant applications of cpg ODN nanorings and development of Leishmania extracellular vesicle based cutaneous leishmaniasis vaccine

GÜRSEL M. (Danışman)

B.GÜNGÖR(Öğrenci)

2016

Yüksek Lisans

Characterisation of immune responses in type i interferon associated diseases

GÜRSEL M. (Danışman)

E.GÜL(Öğrenci)

2015

Yüksek Lisans

Kommensal ve patojen bakterilerden elde edilen bağışıklık hücrelerinin farklı aktivasyonu.

GÜRSEL M. (Danışman)

S.Günalp(Öğrenci)

2015

Yüksek Lisans

Peptidomic characterization and bioactivity screening of Leiurus abdullahbayrami (Scorpiones:Buthidae) venom

ÖZEN C. (Eş Danışman), GÜRSEL M. (Eş Danışman)

E.ERDEŞ(Öğrenci)

2015

Yüksek Lisans

Differential activation of immune cells by commensal versus pathogen-derived DNA

GÜRSEL M. (Danışman)

S.GÜNALP(Öğrenci)

2015

Yüksek Lisans

ATR-FTIR evaluation of structural and functional changes on murine macrophage cells upon activation and suppression by immunotherapeutic oligodeoxynucleotides

GÜRSEL M. (Danışman)

E.SPAHİU(Öğrenci)

2015

Yüksek Lisans

Leiurus abdullahbayrami (scorpiones: buthidae) venomunun peptidomik karakterizasyonu ve biyoaktivite taraması.

ÖZEN C. (Eş Danışman), GÜRSEL M. (Eş Danışman)

E.Erdeş(Öğrenci)

2014

Yüksek Lisans

Differential activation of immune cells by commensal versus pathogen-derived bacterial RNA

GÜRSEL M. (Danışman)

M.ÖZCAN(Öğrenci)

2014

Doktora

Immunotherapeutic applications of nucleic acid based tlr agonists and antagonists

GÜRSEL M. (Danışman)

F.CEM(Öğrenci)

2014

Yüksek Lisans

A study on induction of minicell formation by FTSZ overproducing L-form E. coli

ÖZCENGİZ G. (Eş Danışman), GÜRSEL M. (Eş Danışman)

İ.CEM(Öğrenci)

2013

Yüksek Lisans

Immunomodulatory effects of commensal bacteria-derived membrane vesicles

GÜRSEL M. (Danışman)

E.ALPDÜNDAR(Öğrenci)

2013

Yüksek Lisans

Cyclic-di-GMP based immune stimulatory formulations as vaccine adjuvants

GÜRSEL M. (Danışman)

S.YILDIZ(Öğrenci)

2012

Yüksek Lisans

Sentetik CpG oligodeoksinükleotid / katyonik peptid komplekslerinin immün sitimülan özelliklerinin belirlenmesi.

GÜRSEL M. (Danışman)

B.Güngör(Öğrenci)

2012

Yüksek Lisans

Determination of immune stimulatory properties of synthetic CpG oligodeoxynucleotide/cationic peptide complexes

GÜRSEL M. (Danışman)

B.GÜNGÖR(Öğrenci)

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

2025

A phase I/II study of CpG/alum-adjuvanted mammalian-derived quadruple antigen carrying virus-like particle COVID-19 vaccine

Yilmaz I. C., İPEKOĞLU E. M., Golcuklu B. S., Bildik T., Aksoy A. G. B., Evcili I., et al.

Vaccine , cilt.49, 2025 (SCI-Expanded)
PlumX Metrics
Captures
Readers: 16
see details

2025

Ruxolitinib treatment ameliorates clinical, immunologic, and transcriptomic aberrations in patients with STAT3 gain-of-function disease

Bayram Catak F., Catak M. C., Babayeva R., Toubia J., Warnock N. I., Celmeli F., et al.

Journal of Allergy and Clinical Immunology , cilt.155, sa.3, ss.784-791, 2025 (SCI-Expanded)
PlumX Metrics
Captures
Readers: 2
see details

2024

5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation

Temizoz B., Shibahara T., Hioki K., Hayashi T., Kobiyama K., Lee M. S. J., et al.

Frontiers in Immunology , cilt.15, 2024 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 8
Captures
Readers: 19
Mentions
News Mentions: 1
see details

2023

DOCK8 deficiency with hypereosinophilia and the syndrome of inappropriate antidiuretic hormone secretion during herpes infection

Yeşil A. M., KAYAOĞLU B., Gül E., Gönç N., Özön A., Tezcan İ., et al.

Turkish Journal of Pediatrics , cilt.65, sa.3, ss.536-541, 2023 (SCI-Expanded)
PlumX Metrics
Captures
Readers: 12
see details

2022

Expanding the Clinical and Immunological Phenotypes and Natural History of MALT1 Deficiency

Sefer A. P., Abolhassani H., Ober F., KAYAOĞLU B., Eltan S. B., Kara A., et al.

JOURNAL OF CLINICAL IMMUNOLOGY , cilt.42, sa.3, ss.634-652, 2022 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 22
Captures
Readers: 25
see details

2022

Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency

Yilmaz N. S., Eltan S. B., KAYAOĞLU B., Geckin B., Heredia R. J., Sefer A. P., et al.

JOURNAL OF CLINICAL IMMUNOLOGY , cilt.42, sa.3, ss.582-596, 2022 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 5
Captures
Readers: 16
Social Media
Shares, Likes & Comments: 24
see details

2022

Development and preclinical evaluation of virus-like particle vaccine against COVID-19 infection

YILMAZ İ. C., İPEKOĞLU E. M., Bulbul A., Turay N., Yildirim M., Evcili I., et al.

ALLERGY , cilt.77, sa.1, ss.258-270, 2022 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 45
Captures
Readers: 106
Social Media
Shares, Likes & Comments: 57
see details

2022

The silent and dangerous inequity around access to COVID-19 testing: A call to action Comment

Batista C., Hotez P., Ben Amor Y., Kim J. H., Kaslow D., Lall B., et al.

ECLINICALMEDICINE , cilt.43, 2022 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 39
Policy Citations: 1
Captures
Readers: 62
Mentions
Blog Mentions: 1
News Mentions: 17
Social Media
Shares, Likes & Comments: 6
see details

2021

COVID-19 Vaccine Inequity: High time to calibrate the global moral compass

GÜRSEL M.

EUROPEAN JOURNAL OF IMMUNOLOGY , cilt.51, sa.12, ss.2705-2707, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 2
Captures
Readers: 4
see details

2021

Achieving global equity for COVID-19 vaccines: Stronger international partnerships and greater advocacy and solidarity are needed

Figueroa J. P., Hotez P. J., Batista C., Ben Amor Y., Ergonul O., Gilbert S., et al.

PLOS MEDICINE , cilt.18, sa.9, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 12
Captures
Readers: 79
Mentions
News Mentions: 1
Social Media
Shares, Likes & Comments: 11
see details

2021

Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic

Hotez P. J., Batista C., Ben Amor Y., Ergonul O., Figueroa J. P., Gilbert S., et al.

ECLINICALMEDICINE , cilt.39, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 56
Policy Citations: 3
Captures
Readers: 259
Mentions
References: 1
Social Media
Shares, Likes & Comments: 57
see details

2021

Operation Warp Speed: implications for global vaccine security

Kim J. H., Hotez P., Bottazzi M. E., Lall B., Sheahan T., Shoham S., et al.

LANCET GLOBAL HEALTH , cilt.9, sa.7, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 109
Policy Citations: 25
Captures
Readers: 235
Mentions
Blog Mentions: 6
News Mentions: 55
References: 3
Social Media
Shares, Likes & Comments: 63
see details

2021

Beyond the jab: A need for global coordination of pharmacovigilance for COVID-19 vaccine deployment Comment

Naniche D., Hotez P., Bottazzi M. E., Ergonul O., Figueroa J. P., Gilbert S., et al.

ECLINICALMEDICINE , cilt.36, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 14
Policy Citations: 2
Captures
Readers: 59
Social Media
Shares, Likes & Comments: 39
see details

2021

Urgent needs to accelerate the race for COVID-19 therapeutics

Batista C., Shoham S., Ergonul O., Hotez P., Bottazzi M. E., Figueroa P., et al.

ECLINICALMEDICINE , cilt.36, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 10
Captures
Readers: 42
Mentions
Blog Mentions: 1
Social Media
Shares, Likes & Comments: 31
see details

2021

Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation

KAYAOĞLU B., Kasap N., Yilmaz N. S., Charbonnier L. M., Geckin B., Akcay A., et al.

JOURNAL OF CLINICAL IMMUNOLOGY , cilt.41, sa.4, ss.769-779, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 34
Captures
Readers: 26
see details

2021

Correcting COVID-19 vaccine misinformation Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force Members

Hotez P., Batista C., Ergonul O., Figueroa J. P., Gilbert S., GÜRSEL M., et al.

ECLINICALMEDICINE , cilt.33, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 63
Policy Citations: 5
Captures
Readers: 141
Mentions
Blog Mentions: 1
News Mentions: 3
Social Media
Shares, Likes & Comments: 231
see details

2021

Urgent needs of low-income and middle-income countries for COVID-19 vaccines and therapeutics

Figueroa J. P., Bottazzi M. E., Hotez P., Batista C., Ergonul O., Gilbert S., et al.

LANCET , cilt.397, sa.10274, ss.562-564, 2021 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 92
Policy Citations: 7
Captures
Readers: 189
Mentions
Blog Mentions: 2
News Mentions: 2
References: 1
Social Media
Shares, Likes & Comments: 3
see details

2020

Dual-adjuvant effect of pH-sensitive liposomes loaded with STING and TLR9 agonists regress tumor development by enhancing Th1 immune response.

Kocabas B., Almacioglu K., Bulut E. A., Gucluler G., Tincer G., Bayik D., et al.

Journal of controlled release : official journal of the Controlled Release Society , cilt.328, ss.587-595, 2020 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 52
Patent Family Citations: 1
Captures
Readers: 48
see details

2020

Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells

Bulut E. A., Kocabas B., Yazar V., Aykut G., GÜLER Ü., SALİH B., et al.

JOURNAL OF IMMUNOLOGY , cilt.205, sa.10, ss.2707-2718, 2020 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 47
Captures
Readers: 62
see details

2020

Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic?

GÜRSEL M., GÜRSEL İ.

ALLERGY , cilt.75, sa.7, ss.1815-1819, 2020 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 98
Policy Citations: 4
Captures
Readers: 220
Mentions
News Mentions: 1
Social Media
Shares, Likes & Comments: 99
see details

2020

Autoinflammation in addition to combined immunodeficiency: SLC29A3 gene defect

Cagdas D., Surucu N., TAN Ç., ÖZGÜL R. K., Akkaya-Ulum Y. Z., Aydinoglu A. T., et al.

MOLECULAR IMMUNOLOGY , cilt.121, ss.28-37, 2020 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 22
Captures
Readers: 32
see details

2020

A suppressive oligodeoxynucleotide expressing TTAGGG motifs modulates cellular energetics through the mTOR signaling pathway

Yazar V., Kilic G., Bulut O., Yildirim T. C., Yagci F. C., Aykut G., et al.

INTERNATIONAL IMMUNOLOGY , cilt.32, sa.1, ss.39-48, 2020 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 9
Captures
Readers: 16
see details

2018

Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency

Gul E., Sayar E. H., Gungor B., Eroglu F. K., Surucu N., Keleş S., et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY , cilt.142, ss.246-257, 2018 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 45
Captures
Readers: 73
Mentions
News Mentions: 1
see details

2017

Encapsulation of two different TLR ligands into liposomes confer protective immunity and prevent tumor development

Bayyurt B., Tincer G., Almacioglu K., Alpdundar E., GÜRSEL M., GÜRSEL İ.

Journal of Controlled Release , cilt.247, ss.134-144, 2017 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 51
Captures
Readers: 76
Mentions
News Mentions: 1
see details

2017

Impaired toll like receptor-7 and 9 induced immune activation in chronic spinal cord injured patients contributes to immune dysfunction

Gucluler G., Adiguzel E., Gungor B., Kahraman T., GÜRSEL M., Yilmaz B., et al.

PLOS ONE , cilt.12, sa.2, 2017 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 10
Captures
Readers: 41
Social Media
Shares, Likes & Comments: 2
see details

2017

Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behcet's disease severity

Kahraman T., Gucluler G., ŞİMŞEK I., Yagci F. C., Yildirim M., ÖZEN C., et al.

JOURNAL OF EXTRACELLULAR VESICLES , cilt.6, 2017 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 16
Captures
Readers: 40
Social Media
Shares, Likes & Comments: 1
see details

2016

Intestinal Microbiota in Patients with Spinal Cord Injury

Gungor B., Adiguzel E., Gürsel İ., Yilmaz B., Gürsel M.

PLOS ONE , cilt.11, 2016 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 140
Captures
Readers: 174
Social Media
Shares, Likes & Comments: 1
see details

2015

Enhanced immunostimulatory activity of cyclic dinucleotides on mouse cells when complexed with a cell-penetrating peptide or combined with CpG

Yildiz S., Alpdundar E., Gungor B., Kahraman T., Bayyurt B., GÜRSEL İ., et al.

European Journal of Immunology , cilt.45, sa.4, ss.1170-1179, 2015 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 32
Patent Family Citations: 1
Captures
Readers: 74
see details

2014

Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings

Gungor B., Yagci F. C., GÜRSEL İ., GÜRSEL M.

ONCOIMMUNOLOGY , cilt.3, sa.7, 2014 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 7
Captures
Readers: 16
see details

2014

CpG ODN nanorings induce IFNα from plasmacytoid dendritic cells and demonstrate potent vaccine adjuvant activity

Gungor B., Yagci F. C., Tincer G., Bayyurt B., Alpdundar E., Yildiz S., et al.

Science Translational Medicine , cilt.6, sa.235, 2014 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 65
Patent Family Citations: 1
Captures
Readers: 102
Social Media
Shares, Likes & Comments: 5
see details

2013

Anticarcinogenic Effects of the Ethanolic Extract of Salix aegyptiaca in Colon Cancer Cells: Involvement of Akt/PKB and MAPK Pathways

Enayat S., Ceyhan M. S., BAŞARAN A. A., GÜRSEL M., BANERJEE S.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL , cilt.65, sa.7, ss.1045-1058, 2013 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 28
Captures
Readers: 32
see details

2013

Plasmacytoid Dendritic Cell Response to CpG ODN Correlates with CXCL16 Expression and Is Inhibited by ox-LDL

GÜRSEL M., Klinman D. M., GÜRSEL İ.

MEDIATORS OF INFLAMMATION , 2013 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 2
Usage
Abstract Views: 31
Captures
Readers: 18
see details

2012

Activation of type I interferon-dependent genes characterizes the "core response" induced by CpG DNA.

Steinhagen F., Meyer C., Tross D., Gursel M., Maeda T., Klaschik S., et al.

Journal of leukocyte biology , cilt.92, ss.775-85, 2012 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 18
Captures
Readers: 35
see details

2011

Differential immune activation following encapsulation of immunostimulatory CpG oligodeoxynucleotide in nanoliposomes.

Erikçi E., Gursel M., Gürsel I.

Biomaterials , cilt.32, ss.1715-23, 2011 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 43
Captures
Readers: 45
see details

2010

Mammalian telomeric DNA suppresses endotoxin-induced uveitis.

Yagci F., Aslan O., Gursel M., Tincer G., Ozdamar Y., Karatepe K., et al.

The Journal of biological chemistry , cilt.285, ss.28806-11, 2010 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 9
Captures
Readers: 19
see details

2010

Immune regulatory roles of microparticles in autoimmune and allergic diseases

Kahraman T., Simsek I., GÜRSEL M., Hakan E., Pay S., Dinc A., et al.

JOURNAL OF IMMUNOLOGY , cilt.184, 2010 (SCI-Expanded)

2010

Immunoregulatory Activities of Self-Nanoparticle Forming CpG ODN

GÜRSEL M., Tincer G., Karatepe K., GÜRSEL M.

JOURNAL OF IMMUNOLOGY , cilt.184, 2010 (SCI-Expanded)

2010

Rapid differentiation of MSC into adipocytes and osteocytes is facilitated by Toll-Like receptor engagement

Tas I., Tokcaer-Keskin Z., Ayhan F., GÜRSEL M., Akcali K., GÜRSEL M.

JOURNAL OF IMMUNOLOGY , cilt.184, 2010 (SCI-Expanded)

2006

CXCL16 influences the nature and specificity of CpG-induced immune activation.

Gursel M., Gursel I., Mostowski H., Klinman D.

Journal of immunology (Baltimore, Md. : 1950) , cilt.177, ss.1575-80, 2006 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 66
Captures
Readers: 45
see details

2005

Effect of plasmid backbone modification by different human CpG motifs on the immunogenicity of DNA vaccine vectors.

Coban C., Ishii K., Gursel M., Klinman D., Kumar N.

Journal of leukocyte biology , cilt.78, ss.647-55, 2005 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 63
Usage
Abstract Views: 3
Captures
Readers: 58
see details

2005

Suppressive oligodeoxynucleotides protect mice from lethal endotoxic shock.

Shirota H., Gursel I., Gursel M., Klinman D.

Journal of immunology (Baltimore, Md. : 1950) , cilt.174, ss.4579-83, 2005 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 85
Captures
Readers: 39
see details

2005

CpG RNA: identification of novel single-stranded RNA that stimulates human CD14+CD11c+ monocytes.

Sugiyama T., Gursel M., Takeshita F., Coban C., Conover J., Kaisho T., et al.

Journal of immunology (Baltimore, Md. : 1950) , cilt.174, ss.2273-9, 2005 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 77
Captures
Readers: 51
Mentions
News Mentions: 1
see details

2005

CpG oligodeoxynucleotides enhance neonatal resistance to Listeria infection.

Ito S., Ishii K., Gursel M., Shirotra H., Ihata A., Klinman D.

Journal of immunology (Baltimore, Md. : 1950) , cilt.174, ss.777-82, 2005 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 55
Captures
Readers: 19
see details

2004

Suppressive oligodeoxynucleotides inhibit Th1 differentiation by blocking IFN-gamma- and IL-12-mediated signaling.

Shirota H., Gursel M., Klinman D.

Journal of immunology (Baltimore, Md. : 1950) , cilt.173, ss.5002-7, 2004 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 68
Patent Family Citations: 2
Captures
Readers: 25
see details

2004

Immunotherapeutic utility of stimulatory and suppressive oligodeoxynucleotides.

Ishii K., Gursel I., Gursel M., Klinman D.

Current opinion in molecular therapeutics , cilt.6, ss.166-74, 2004 (SCI-Expanded)

2004

Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9.

Takeshita F., Gursel I., Ishii K., Suzuki K., Gursel M., Klinman D.

Seminars in immunology , cilt.16, ss.17-22, 2004 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 164
Captures
Readers: 110
Mentions
References: 2
see details

2003

Regulation of CpG-induced immune activation by suppressive oligodeoxynucleotides.

Klinman D., Zeuner R., Yamada H., Gursel M., Currie D., Gursel I.

Annals of the New York Academy of Sciences , cilt.1002, ss.112-23, 2003 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 31
Patent Family Citations: 1
Captures
Readers: 9
see details

2003

Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation.

Gursel I., Gursel M., Yamada H., Ishii K., Takeshita F., Klinman D.

Journal of immunology (Baltimore, Md. : 1950) , cilt.171, ss.1393-400, 2003 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 219
Captures
Readers: 100
see details

2003

Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis.

Zeuner R., Verthelyi D., Gursel M., Ishii K., Klinman D.

Arthritis and rheumatism , cilt.48, ss.1701-7, 2003 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 60
Captures
Readers: 12
see details

2003

CpG oligodeoxynucleotides protect normal and SIV-infected macaques from Leishmania infection.

Verthelyi D., Gursel M., Kenney R., Lifson J., Liu S., Mican J., et al.

Journal of immunology (Baltimore, Md. : 1950) , cilt.170, ss.4717-23, 2003 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 108
Captures
Readers: 59
see details

2003

Response of peripheral blood mononuclear cells from lupus patients to stimulation by CpG oligodeoxynucleotides.

Zeuner R., Klinman D., Illei G., Yarboro C., Ishii K., Gursel M., et al.

Rheumatology (Oxford, England) , cilt.42, ss.563-9, 2003 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 26
Captures
Readers: 21
see details

2002

Effect of suppressive DNA on CpG-induced immune activation.

Yamada H., Gursel I., Takeshita F., Conover J., Ishii K., Gursel M., et al.

Journal of immunology (Baltimore, Md. : 1950) , cilt.169, ss.5590-4, 2002 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 99
Captures
Readers: 44
see details

2002

CpG oligodeoxynucleotides induce human monocytes to mature into functional dendritic cells.

Gursel M., Verthelyi D., Klinman D.

European journal of immunology , cilt.32, ss.2617-22, 2002 (SCI-Expanded)

2002

Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation.

Ishii K., Takeshita F., Gursel I., Gursel M., Conover J., Nussenzweig A., et al.

The Journal of experimental medicine , cilt.196, ss.269-74, 2002 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 126
Captures
Readers: 45
see details

2002

CpG DNA: recognition by and activation of monocytes.

Klinman D., Takeshita F., Gursel I., Leifer C., Ishii K., Verthelyi D., et al.

Microbes and infection , cilt.4, ss.897-901, 2002 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 69
Captures
Readers: 39
see details

2002

Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide

GÜRSEL M., Verthelyi D., Gursel I., Ishii K., Klinman D.

JOURNAL OF LEUKOCYTE BIOLOGY , cilt.71, sa.5, ss.813-820, 2002 (SCI-Expanded)

2001

Cutting edge: Role of toll-like receptor 9 in CpG DNA-induced activation of human cells

Takeshita F., Leifer C., Gursel I., Ishii K., Takeshita S., Gursel M., et al.

JOURNAL OF IMMUNOLOGY , cilt.167, sa.7, ss.3555-3558, 2001 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 534
Patent Family Citations: 1
Captures
Readers: 175
see details

2001

Sterically stabilized cationic liposomes improve the uptake and immunostimulatory activity of CpG oligonucleotides

Gursel I., Gursel M., Ishii K., Klinman D.

JOURNAL OF IMMUNOLOGY , cilt.167, sa.6, ss.3324-3328, 2001 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 172
Captures
Readers: 62
see details

2001

Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs

Verthelyi D., Ishii K., Gursel M., Takeshita F., Klinman D.

JOURNAL OF IMMUNOLOGY , cilt.166, sa.4, ss.2372-2377, 2001 (SCI-Expanded)

2000

Activation of the innate immune system by CpG oligodeoxynucleotides: immunoprotective activity and safety

Klinman D., Kamstrup S., Verthelyi D., Gursel I., Ishii K., Takeshita F., et al.

SPRINGER SEMINARS IN IMMUNOPATHOLOGY , cilt.22, ss.173-183, 2000 (SCI-Expanded)

2000

Immunotherapeutic applications of CpG-containing oligodeoxynucleotides

Klinman D., Ishii K., Gursel M., Gursel I., Takeshita S., Takeshita F.

DRUG NEWS & PERSPECTIVES , cilt.13, sa.5, ss.289-296, 2000 (SCI-Expanded)

1999

Immunoadjuvant action of plasmid DNA in liposomes

Gursel M., Tunca S., Ozkan M., Ozcengiz G., Alaeddinoglu G.

VACCINE , cilt.17, ss.1376-1383, 1999 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 51
Captures
Readers: 13
see details

1998

The immunological co-adjuvant action of liposomal interleukin-2: The role of mode of localisation of the cytokine and antigen in the vesicles

Gursel M., Gregoriadis G.

JOURNAL OF DRUG TARGETING , cilt.5, sa.2, ss.93-98, 1998 (SCI-Expanded)

1997

Interleukin-15 acts as an immunological co-adjuvant for liposomal antigen in vivo

Gursel M., Gregoriadis G.

IMMUNOLOGY LETTERS , cilt.55, sa.3, ss.161-165, 1997 (SCI-Expanded)

1996

Liposomes as immunological adjuvants and vaccine carriers

Gregoriadis G., Gursel I., GÜRSEL M., McCormack B.

JOURNAL OF CONTROLLED RELEASE , cilt.41, ss.49-56, 1996 (SCI-Expanded)

1995

INFLUENCE OF MEMBRANE-COMPONENTS ON THE STABILITY AND DRUG-RELEASE PROPERTIES OF REVERSE-PHASE EVAPORATION VESICLES (REVS) - LIGHT-SENSITIVE ALL-TRANS RETINAL, NEGATIVELY CHARGED PHOSPHOLIPID DICETYLPHOSPHATE AND CHOLESTEROL

GURSEL M., HASIRCI V.

JOURNAL OF MICROENCAPSULATION , cilt.12, sa.6, ss.661-669, 1995 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 4
Captures
Readers: 6
see details

1995

A NONIONIC SURFACTANT VESICLE-IN-WATER-IN-OIL (V/W/O) SYSTEM - POTENTIAL USES IN DRUG AND VACCINE DELIVERY

YOSHIOKA T., SKALKO N., GURSEL M., GREGORIADIS G., FLORENCE A.

JOURNAL OF DRUG TARGETING , cilt.2, sa.6, ss.533-539, 1995 (SCI-Expanded)
PlumX Metrics
Citations
Citation Indexes: 31
Captures
Readers: 13
see details

Diğer Dergilerde Yayınlanan Makaleler

2020

Could Individuals From Countries Using BCG Vaccination Be Resistant to SARS-COV-2 Induced Infections?

AYANOĞLU İ. C., İPEKOĞLU E. M., Yazar V., Yilmaz I. C., GÜRSEL M., GÜRSEL M.

TURKISH JOURNAL OF IMMUNOLOGY , cilt.8, sa.1, ss.29-36, 2020 (ESCI)
PlumX Metrics
Citations
Citation Indexes: 1
Captures
Readers: 38
see details

2016

Development of CpG ODN Based Vaccine Adjuvant Formulations.

Gursel M., Gursel I.

Methods in molecular biology (Clifton, N.J.) , cilt.1404, ss.289-98, 2016 (Scopus)

2015

Biological properties of extracellular vesicles and their physiological functions

Yanez-Mo M., Siljander P. R. -., Andreu Z., Zavec A. B., Borras F. E., Buzas E. I., et al.

JOURNAL OF EXTRACELLULAR VESICLES , cilt.4, 2015 (ESCI)

1997

Interleukin-15 acts as an immunological co-adjuvant for liposomal antigen in vivo

GÜRSEL M., Gregoriadis G.

Proceedings of the Controlled Release Society , sa.24, ss.1047-1048, 1997 (Scopus)

1995

Immunoadjuvant action of liposomes containing interleukin-2 as a co-adjuvant

Gursel M., Gregoriadis G.

Proceedings of the Controlled Release Society , sa.22, ss.572-573, 1995 (Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler

2019

Role of cytosolic innate immune sensing pathways in Leismania major infection

Yilmaz I. C., Gursel M.

17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), Beijing, Çin, 19 - 23 Ekim 2019, cilt.49, ss.1202

2019

Functional analysis of inflammation associated parameters in a case of NEMO deficiency before and after HSCT

Surucu N., Kayaoglu B., Geckin B., Ayanoglu I. C., Eltan S. B., Kasap N., et al.

17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), Beijing, Çin, 19 - 23 Ekim 2019, cilt.49, ss.1232-1233

2018

Evaluation of fetomaternal microchimeric cell potential on maternal wound healing by creating an amniotic fluid environment in a randomized-controlled murine model – postulating an overlooked paradigm on maternal wounds

ÖZER K., BULUT Ö., ATAN O., ERDOĞAN OĞUZ A. S., KOÇER R. G., GÜRSEL M., et al.

10th Anniversary of the European Plastic Surgery Research Council (EPSRC), Hamburg, Almanya, 23 - 25 Ağustos 2018

2017

Impaired Toll Like Receptor-7 and 9 Induced Immune Activation in Chronic Spinal Cord Injured Patients Contributes to Immune Dysfunction

GÜÇLÜLER G., ADIGÜZEL E., GÜNGÖR B., KAHRAMAN T., GÜRSEL M., YILMAZ B., et al.

26. ULUSAL FİZİKSEL TIP ve REHABİLİTASYON KONGRESİ, Antalya, Türkiye, 25 Nisan 2017

2016

Characterization of L. tropica secreted exosomes and development of exosome-based preventive vaccine against L. tropica induced cutaneous leishmaniasis

Gungor B., AYANOĞLU İ. C., Konig T. G., ÖZBEL Y., ÖZBİLGİN A., GİRGİNKARDEŞLER N., et al.

International Congress of Immunology (ICI), Melbourne, Avustralya, 21 - 26 Ağustos 2016, cilt.46, ss.1218

2016

Type I interferon associated immune responses In STING associated vasculopathy with onset in infancy (SAVI) patients

Gul E., Eroglu K. F., Surucu N., Yakicier C., GÜRSEL İ., ÖZEN S., et al.

International Congress of Immunology (ICI), Melbourne, Avustralya, 21 - 26 Ağustos 2016, cilt.46, ss.904

2014

REVERSING THE PROGRESS OF LIVER FIBROSIS USING MEMBRANE VESICLES SECRETED FROM COMMENSAL BACTERIA

Aydin M. M., Alpdundar E., GÜRSEL M., AKÇALI K. C.

49th Annual International Liver Congress of the European-Association-for-the-Study-of-the-Liver, London, Kanada, 9 - 13 Nisan 2014, cilt.60

2006

CXCL16 influences the nature and specificity of CpG DNA-induced immune activation

GÜRSEL M., GÜRSEL M., Klinman D. M.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.67

2006

Immunotherapeutic applications of CpG ODN

GÜRSEL M., GÜRSEL M., Klinman D. M.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.68

1996

The immunological co-adjuvant action of liposomal interleukin-15

GÜRSEL M., Gregoriadis G.

5th NATO Advanced Studies Institute Workshop on Vaccine Design - The Role of Cytokine Networks, CAPE SOUNION BEACH, Yunanistan, 24 Haziran - 05 Temmuz 1996, cilt.293, ss.175-180

1994

Interleukin-2 as a Co-adjuvant for liposomal tetanus toxoid

GÜRSEL M., Gregoriadis G.

NATO Advanced Study Institute on Vaccines - New Generation Immunological Adjuvants, CAPE SOUNION, Yunanistan, 24 Haziran - 05 Temmuz 1994, cilt.282, ss.45-50

Desteklenen Projeler

2021 - 2022

SARSCoV2 yapısal yapısal olmayan ve aksesuar proteinlerinin makrofaj enflamazom aktivasyonu üzerine etkilerinin incelenmesi

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2020 - 2021

Sentetik ODN A151 ile NF-kB sinyalizasyon yolağının baskılanması ve mekanizma önerisi

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü), SÜRÜCÜ N.

2018 - 2019

Meme dokusunun gelişim aşamalarının APA açısından analizi

Yükseköğretim Kurumları Destekli Proje

ERSON BENSAN A. E. (Yürütücü), KİRİŞ E., MUYAN M., GÜRSEL M., TERZİ ÇİZMECİOĞLU N., BANERJEE S.

2017 - 2017

TİP-I İNTERFERON İLİŞKİLİ HASTALIKLARDA İMMÜN PATOLOJİYE NEDEN OLAN YOLAKLARIN KARAKTERİZASYONU

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2017 - 2017

LEİSHMANİA KİNETOPLAST DNA'SININ BAĞIŞIKLIK SİSTEMİ ÜZERİNDEKİ DÜZENLEYİCİ ETKİSİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2017 - 2017

HÜCRE İÇİ DNA SENSÖRLERİNİN SİNYAL İLETİM YOLAKLARININ ÇALIŞILMASI AMACIYLA in Vitro STABİL HÜCRE HATTI OLUŞTURULMASI

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2017 - 2017

İNSAN MİKROBİYOMU KÖKENLİ MEMBRAN KESECİKLERİNİN İMMÜN MODÜLATÖR ETKİLERİ: ETKİ MEKANİZMASI VE TERAPÖTİK UYGULAMALAR

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2017 - 2017

İMMÜN BASKILAYICI SENTETİK OLİGODEOKSİNÜKLEOTİT A151'İN ÇEŞİTLİ INFLAMAZON KOMKLEKSLERİ ÜZERİNDEKİ İMMÜN BASKILATICI ETKİLERİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2016 - 2016

Kurşun ve Kadmiyum Ağır Metallerinin Yüksek Derişimlerine alıştırılmış Çevresel Bakterilerde Maruziyet Altındaki Fizyolojik Uyumlamanın Moleküler Kökenleri

Yükseköğretim Kurumları Destekli Proje

GÖZEN A. G. (Yürütücü), BEKLİOĞLU M., KEPENEK E. Ş., İZGÜ K. F., GÜNDÜZ U., GÜRSEL M., et al.

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2015 - 2015

Tatlısu Acinetobacter türlerinin antibiyotik maruziyeti altında sergiledikleri moleküler değişimlerin belirlenmesi

Yükseköğretim Kurumları Destekli Proje

GÖZEN A. G. (Yürütücü), BEKLİOĞLU M., İZGÜ K. F., GÜRSEL M., DOĞAN M., ÖZCENGİZ G., et al.

2014 - 2015

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2015

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2015

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2015

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2014 - 2015

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2013 - 2014

Sucul biofilm bakterilerinin arsenik, nikel ve kadmiyum dirençlerinin belirlenmesi ve moleküler karakterizasyonu

Yükseköğretim Kurumları Destekli Proje

GÖZEN A. G. (Yürütücü), ÖKTEM H. A., BUCAK T., COPPENS J. E. P., KALVENAS J. E., İZGÜ K. F., et al.

2013 - 2014

SPINAL KORD YARALANMALI (SKY) BIREYLERDE BARSAK FLORASININ TANIMLANMASI

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2013 - 2013

TÜMÖRE YÖNLENDİRİLMİŞ CpG OLİGODEOKSİNÜKLEOTİD /KATYONİK PEPTİD KOMPLEKSLERİNİN TERAPATİK ÖZELLİKLERİNİN BELİRLENMESİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü), GÜNGÖR B.

2013 - 2013

MİCROBİYAL HÜCRE KÖKENLİ SALGI KESECİKLERİNİN İMMUNOMODÜLATÖR ETKİLERİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü), ALPDÜNDAR E.

2013 - 2013

METAL-ORGANİK KOORDİNASYON NANOPARÇACIKLARIN IMMUN MODULATOR ETKİLERİ

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü), YILDIZ S.

2012 - 2012

Rekombinant Protein Antijenlerin Ve Yeni Tip Adjuvantların Aşı Uygulama Çalışmalarında Denenmesi

Yükseköğretim Kurumları Destekli Proje

GÜRSEL M. (Yürütücü)

2011 - 2011