Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings


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Gungor B., Yagci F. C. , GÜRSEL İ., GÜRSEL M.

ONCOIMMUNOLOGY, vol.3, no.7, 2014 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Editorial Material
  • Volume: 3 Issue: 7
  • Publication Date: 2014
  • Doi Number: 10.4161/21624011.2014.950166
  • Title of Journal : ONCOIMMUNOLOGY

Abstract

Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications. We recently described a simple strategy to convert a Toll-like receptor 9 (TLR9) agonist devoid of interferon alpha (IFN alpha) stimulating activity into a robust Type I interferon inducer with potent vaccine adjuvant activity.