Prof. Dr. TOLGA CAN

Yayın Ağı

Makaleler 33

1. Effective primer design for genotype and subtype detection of highly divergent viruses in large scale genome datasets

Demiralay B., Can T.

BMC Bioinformatics , cilt.26, sa.1, 2025 (SCI-Expanded, Scopus)

2. Phosphorylation of SNAP-25 at Ser187 is enhanced following its cleavage by Botulinum Neurotoxin Serotype A, promoting the dominant-negative effect of the resulting fragment

Koc D., EZGİN S., Kavakli E., Kota K. P., Sen E., Mahone C., et al.

PLOS Pathogens , cilt.21, sa.10 October, 2025 (SCI-Expanded, Scopus)

3. Differential expression of mRNA 3′-end isoforms in cervical and ovarian cancers

Döken D. N., Özgül İ., Köksal Bıçakcı G., Gol K., Can T., Erson Bensan A. E.

Heliyon , cilt.9, sa.9, 2023 (SCI-Expanded, Scopus)

4. Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer

Assidicky R., Tokat U. M., Tarman I. O., Saatci O., Ersan P. G., Raza U., et al.

BREAST CANCER RESEARCH AND TREATMENT , cilt.193, sa.2, ss.331-348, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

5. A C-term truncated EIF2Bγ protein encoded by an intronically polyadenylated isoform introduces unfavorable EIF2Bγ-EIF2γ interactions.

Circir A., Bicakci G. K., Savas B., Doken D. N., Henden O., Can T., et al.

Proteins , cilt.90, sa.3, ss.889-897, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

6. Identification of an mRNA isoform switch for HNRNPA1 in breast cancers

Erdem M., Ozgul İ., Dioken D. N., Gurcuoglu I., Guntekin Ergun S., Cetin-Atalay R., et al.

Scientific Reports , cilt.11, sa.1, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

7. MotifGenie: A Python Application for Searching Transcription Factor Binding Sequences Using ChIP-Seq Datasets.

Oguztuzun C., Yasar P., Yavuz K., Muyan M., Can T.

Bioinformatics (Oxford, England) , cilt.37, ss.4238-4239, 2021 (SCI-Expanded, Scopus)

8. A prelude to the proximity interaction mapping of CXXC5

Ayaz G., Turan G., OLGUN Ç. E., Kars G., Karakaya B., Yavuz K., et al.

SCIENTIFIC REPORTS , cilt.11, sa.1, 2021 (SCI-Expanded, Scopus)

9. A CpG island promoter drives the CXXC5 gene expression

Yasar P., Kars G., Yavuz K., Ayaz G., Oguztuzun C., Bilgen E., et al.

SCIENTIFIC REPORTS , cilt.11, sa.1, 2021 (SCI-Expanded, Scopus)

10. JOA: Joint Overlap Analysis of multiple genomic interval sets

Otlu B., Can T.

BMC BIOINFORMATICS , cilt.20, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

11. Alternative Polyadenylation Patterns for Novel Gene Discovery and Classification in Cancer

BEGIK O., ÖYKEN M., ALICAN T. C., CAN T., Erson-Bensan A. E.

NEOPLASIA , cilt.19, sa.7, ss.574-582, 2017 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. A multiplex primer design algorithm for target amplification of continuous genomic regions

OZTURK A. R., CAN T.

BMC BIOINFORMATICS , cilt.18, 2017 (SCI-Expanded, Scopus)

13. Comparison of tissue/disease specific integrated networks using directed graphlet signatures

Sonmez A. B., Can T.

BMC BIOINFORMATICS , cilt.18, 2017 (SCI-Expanded, Scopus)

14. SUMONA: A supervised method for optimizing network alignment

TUNCAY E. G., Can T.

COMPUTATIONAL BIOLOGY AND CHEMISTRY , cilt.63, ss.41-51, 2016 (SCI-Expanded, Scopus)

15. Alternative Polyadenylation: Another Foe in Cancer

Erson-Bensan A. E., CAN T.

MOLECULAR CANCER RESEARCH , cilt.14, sa.6, ss.507-517, 2016 (SCI-Expanded, Scopus)

16. 3 ' UTR shortening and EGF signaling: implications for breast cancer

AKMAN H. B., ÖYKEN M., TUNCER T., CAN T., Erson-Bensan A. E.

HUMAN MOLECULAR GENETICS , cilt.24, sa.24, ss.6910-6920, 2015 (SCI-Expanded, Scopus)

17. Reconstruction of the temporal signaling network in Salmonella-infected human cells

Budak G., Ozsoy O. E., Son Y., Can T., Tunçbağ N.

FRONTIERS IN MICROBIOLOGY , cilt.6, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

18. Informatics Olympiads in Turkey Team Selection and Training

CAN T., SIĞIRCI İ. O., ABUL O., DEMİRCİ M. F.

OLYMPIADS IN INFORMATICS , cilt.9, ss.225-232, 2015 (Hakemli Dergi)

19. The CHEMDNER corpus of chemicals and drugs and its annotation principles

Krallinger M., Rabal O., Leitner F., Vazquez M., Salgado D., Lu Z., et al.

JOURNAL OF CHEMINFORMATICS , cilt.7, 2015 (SCI-Expanded, Scopus)

20. Div-BLAST: Diversification of Sequence Search Results

Eser E., CAN T., Ferhatosmanoglu H.

PLOS ONE , cilt.9, sa.12, 2014 (SCI-Expanded, Scopus)

21. GPCRsort-Responding to the Next Generation Sequencing Data Challenge: Prediction of G Protein-Coupled Receptor Classes Using Only Structural Region Lengths

Sahın M. E., Can T., Son Ç. D.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY , cilt.18, ss.636-644, 2014 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

22. Identification of Novel Reference Genes Based on MeSH Categories

Ersahin T., ÇARKACIOĞLU L., CAN T., Konu O., Atalay V., Cetin-Atalay R.

PLOS ONE , cilt.9, sa.3, 2014 (SCI-Expanded, Scopus)

23. A Divide and Conquer Approach for Construction of Large-Scale Signaling Networks from PPI and RNAi Data Using Linear Programming

Ozsoy O. E., Can T.

IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS , cilt.10, ss.869-883, 2013 (SCI-Expanded, Scopus)

24. Large-Scale Signaling Network Reconstruction

Hashemikhabir S., Ayaz E. S., Kavurucu Y., Can T., Kahveci T.

IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS , cilt.9, ss.1696-1708, 2012 (SCI-Expanded, Scopus)

25. Estrogen-induced upregulation and 3 '-UTR shortening of CDC6

AKMAN B. H., CAN T., Erson-Bensan A. E.

NUCLEIC ACIDS RESEARCH , cilt.40, sa.21, ss.10679-10688, 2012 (SCI-Expanded, Scopus)

26. Using network context as a filter for miRNA target prediction

Sualp M., Can T.

BIOSYSTEMS , cilt.105, ss.201-209, 2011 (SCI-Expanded, Scopus)

27. METADATA MANAGEMENT AND SEMANTICS IN MICROARRAY REPOSITORIES

Kocabas F., CAN T., BAYKAL N.

BALKAN JOURNAL OF MEDICAL GENETICS , cilt.14, sa.2, ss.49-63, 2011 (SCI-Expanded, Scopus)

28. Bi-k-bi clustering: mining large scale gene expression data using two-level biclustering

Carkacioglu L., Atalay R. C., KONU KARAKAYALI Ö., Atalay V., CAN T.

INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS , cilt.4, sa.6, ss.701-721, 2010 (SCI-Expanded, Scopus)

29. RRW: repeated random walks on genome-scale protein networks for local cluster discovery

MACROPOL K., Can T., Singh A. K.

BMC BIOINFORMATICS , cilt.10, 2009 (SCI-Expanded, Scopus)

30. Integration of topological measures for eliminating non-specific interactions in protein interaction networks

BAYIR M. A., GUNEY T. D., Can T.

DISCRETE APPLIED MATHEMATICS , cilt.157, sa.10, ss.2416-2424, 2009 (SCI-Expanded, Scopus)

31. Discovering functional interaction patterns in protein-protein interaction networks

Turanalp M. E., Can T.

BMC BIOINFORMATICS , cilt.9, 2008 (SCI-Expanded, Scopus)

32. Efficient molecular surface generation using level-set methods

Can T., Chen C., Wang Y.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING , cilt.25, sa.4, ss.442-454, 2006 (SCI-Expanded, Scopus)

33. Integrating multi-attribute similarity networks for robust representation of the protein space

Camoglu O., Can T., Singh A. K.

BIOINFORMATICS , cilt.22, sa.13, ss.1585-1592, 2006 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 22

1. HNRNPA1 Isoform Switch in Breast Cancer

ÖZGÜL İ., Erdem M., Döken D. N., GÜRCÜOĞLU I., GÜNTEKİN ERGÜN S., Cetin Atalay R., et al.

Frontiers in Cancer Science 2021, Singapur, 1 - 03 Kasım 2021, cilt.1, ss.28, (Özet Bildiri)

2. Transcription Elongation in Connection to 3’UTR Ends

ÖZGÜL İ., CAN T., ERSON BENSAN A. E.

Moleküler Biyoloji Kongresi MolBiyoKON18, İzmir, Türkiye, 5 - 08 Eylül 2018, ss.20, (Özet Bildiri)

3. Deregulated APA and cancer specific APA isoforms

Begik O., Ercan M., Cingoz H., CAN T., ÖYKEN M., Erson-Bensan A. E.

Annual Meeting of the American-Association-for-Cancer-Research (AACR), Illinois, Amerika Birleşik Devletleri, 14 - 18 Nisan 2018, cilt.78, (Özet Bildiri) Sürdürülebilir Kalkınma

4. Alternative Polyadenylation patterns for cancer classification

BEGIK O., ÖYKEN M., ÇINKILLI t., CAN T., ERSON BENSAN A. E.

HIBIT 2017, 28 - 30 Haziran 2017, (Özet Bildiri) Sürdürülebilir Kalkınma

5. Alternative Polyadenylation patterns for novel gene discovery and classification in cancer

BEĞİK O., ÖYKEN M., CAN T., ERSON BENSAN A. E.

Annual Meeting of the RNA Society, 30 Mayıs - 03 Haziran 2017, (Özet Bildiri) Sürdürülebilir Kalkınma

6. APA isoform diversity in triple negative breast cancers

AKMAN TUNCER H. B., ÖYKEN M., AĞUŞ H. H., ERDEM M., YAVUZ E., CAN T., et al.

AACR Annual Meeting, USA, Washington, Amerika Birleşik Devletleri, 1 - 05 Nisan 2017, cilt.77, ss.3374, (Özet Bildiri) Sürdürülebilir Kalkınma

7. Identification of a potential cancer related lncRNA

BEĞİK O., cinkilli t., ÖYKEN M., CAN T., ERSON BENSAN A. E.

Functional Genomics to Systems Biology-EMBO, 12 - 15 Kasım 2016 Sürdürülebilir Kalkınma

8. Comparison of tissue disease specific integrated networks using directed graphlet signatures

SÖNMEZ A. B., CAN T.

Proceedings of the 7th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics - BCB '16, Seattle, WA, USA, Amerika Birleşik Devletleri, 2 - 05 Ekim 2016

9. 3 UTR Length Changes In Connection With Estrogen Receptor Alpha In Breast Cancer

ÖYKEN M., CAN T., ERSON BENSAN A. E.

FEBS 2016, KUSADASI, Türkiye, 3 - 08 Eylül 2016 Sürdürülebilir Kalkınma

10. 3 ' UTR lengths change in connection with estrogen receptor-alpha in breast cancer

ÖYKEN M., CAN T., Erson-Bensan A. E.

41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.207, (Özet Bildiri) Sürdürülebilir Kalkınma

11. Unsupervised identification of redundant domain entries in InterPro database using clustering techniques

RİFAİOĞLU A. S., DOĞAN T., CAN T.

6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, BCB 2015, Georgia, Amerika Birleşik Devletleri, 9 - 12 Eylül 2015, ss.505-506, (Tam Metin Bildiri)

12. Reconstruction of the Temporal Signaling Network in Salmonella Infected Human Cells

güngör b., EREN ÖZSOY Ö., AYDIN SON Y., CAN T., nurcan t.

23rd Annual International Conference on Intelligent Systems for Molecular Biology and the 14th European Conference on Computational Biology (ISMBECCB’2015), Dublin, İrlanda, 10 - 14 Temmuz 2015

13. Dbchem A database query based solution for the chemical compound and drug name recognition task

ATA Ç., CAN T.

Proceedings of the Fourth BioCreative Challenge Evaluation Workshop, BioCreative IV,, 1 - 03 Ekim 2013, cilt.2, ss.42-46, (Tam Metin Bildiri)

14. M4B: A novel method for designing and ordering of the genetic devices

Hashemikhabir S., Ersoy G., Oguz G., Yaldiz B., Tuncel Y., Budak G., et al.

2012 7th International Symposium on Health Informatics and Bioinformatics, HIBIT 2012, Cappadocia, Türkiye, 19 - 22 Nisan 2012, ss.123-127, (Tam Metin Bildiri)

15. Parallel SPICi

Hashemikhabir S., CAN T.

6th International Symposium on Health Informatics and Bioinformatics (HIBIT), İzmir, Türkiye, 2 - 05 Mayıs 2011, ss.86-90, (Tam Metin Bildiri)

16. CONSTRUCTING SIGNALING PATHWAYS FROM RNAI DATA USING GENETIC ALGORITHMS

Ayaz E. S., CAN T.

6th International Symposium on Health Informatics and Bioinformatics (HIBIT), İzmir, Türkiye, 2 - 05 Mayıs 2011, ss.95-98, (Tam Metin Bildiri)

17. The effect of representative training dataset selection on the classification performance of the promoter sequences

YAMAN A. G., CAN T.

6th International Symposium on Health Informatics and Bioinformatics, HIBIT 2011, İzmir, Türkiye, 2 - 05 Mayıs 2011, ss.55-58, (Tam Metin Bildiri)

18. Coevolution based prediction of protein-protein interactions with reduced training data

Pamuk B., CAN T.

2010 5th International Symposium on Health Informatics and Bioinformatics, HIBIT 2010, Antalya, Türkiye, 20 - 22 Nisan 2010, ss.187-193, (Tam Metin Bildiri)

19. Text Classification in the Turkish Marketing Domain for Context Sensitive Ad Distribution

Engin M., Can T.

24th International Symposium on Computer and Information Sciences, Güzelyurt, Kıbrıs (Kktc), 14 - 16 Eylül 2009, ss.105-110, (Tam Metin Bildiri)

20. Human Skeletal and Muscle Deformation Animation Using Motion Capture Data

Bayer A. O., Sevinc A. M., CAN T.

16th International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision, Plzen, Çek Cumhuriyeti, 4 - 07 Şubat 2008, ss.167-168, (Tam Metin Bildiri)

21. Analysis of protein-protein interaction networks using random walks

Can T., Orhan Ç., Singh A. K.

5th International Workshop on Bioinformatics, BIOKDD 2005 - In Conjunction with 11th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, KDD 2005, Chicago, IL, Amerika Birleşik Devletleri, 21 Ağustos 2005, ss.61-68, (Tam Metin Bildiri)

22. CTSS: A robust and efficient method for protein structure alignment based on local geometrical and biological features

Can T., WANG Y.

2nd International Computational Systems Bioinformatics Conference, California, Amerika Birleşik Devletleri, 11 - 14 Ağustos 2003, ss.169-179, (Tam Metin Bildiri)

Kitaplar 2

1. Hastalıkların Genetik Temellerinin Tanımlanması

KAYA Z., SON Ç. D., KANDEMİR İ., AKKAYA A., AYDIN SON Y., CAN T., et al.

Biyologlar için biyoenformatik, Zeki Kaya, Editör, Nobel, Ankara, ss.3-22, 2015

2. Introduction to Bioinformatics

CAN T.

miRNomics MicroRNA Biology and Computational Analysis, Yousef Malik, Allmer Jens, Editör, Springer Protocols, ss.51-71, 2013

Metrikler

Yayın

Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

666

H-İndeks (WoS)

Atıf (Scopus)

728

H-İndeks (Scopus)

Atıf (Scholar)

146

H-İndeks (Scholar)

Proje

Fikri Mülkiyet

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler