Eğitim Bilgileri
2010 - 2015
2010 - 2015Doktora
Purdue University, Amerika Birleşik Devletleri
2008 - 2010
2008 - 2010Yüksek Lisans
Orta Doğu Teknik Üniversitesi, Türkiye
2004 - 2008
2004 - 2008Lisans
Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Türkiye
Yaptığı Tezler
2015
2015Doktora
Freezing-Induced Deformation of Biomaterials in Cryomedicine
Purdue University
2010
2010Yüksek Lisans
Development of an incompressible, laminar flow solver based on least squares spectral element method with P-type adaptive refinement capabilities
Orta Doğu Teknik Üniversitesi
Yabancı Diller
C2 Ustalık
C2 Ustalıkİngilizce
Araştırma Alanları
Biyoenstrümantasyon ve MEMS
Biyoenstrümantasyon ve MEMS
Biyomedikal Görüntü İşleme
Biyomekanik
Yapay Organlar ve Biyomateryaller
Geleneksel olmayan imalat yöntemleri
Biyomekanik
Isı ve Madde Transferi
Akademik Unvanlar / Görevler
2021 - Devam Ediyor
2021 - Devam EdiyorDr. Öğr. Üyesi
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyomedikal Mühendisliği Anabilim Dalı
2020 - Devam Ediyor
2020 - Devam EdiyorDr. Öğr. Üyesi
Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Makina Mühendisliği Bölümü
2017 - 2019
2017 - 2019Araştırmacı
University of Maryland, College Park, Institute for Physical Science and Technology, Department of Physics
2016 - 2017
2016 - 2017Araştırmacı
Johns Hopkins University, School of Engineering, Department of Mechanical Engineering
2015 - 2016
2015 - 2016Araştırmacı
Purdue University, College of Engineering, School of Mechanical Engineering
2010 - 2015
2010 - 2015Araştırma Görevlisi
Purdue University, College of Engineering, School of Mechanical Engineering
Yönetimsel Görevler
2022 - Devam Ediyor
2022 - Devam EdiyorPublicity and Communication Committee Member
Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Makina Mühendisliği Bölümü
2022 - Devam Ediyor
2022 - Devam EdiyorBiomechanics Track Representative
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyomedikal Mühendisliği Anabilim Dalı
2020 - Devam Ediyor
2020 - Devam EdiyorODTÜ Uzaktan Eğitim Uygulama ve Araştırma Merkezi (ÜZEM) Danışma Kurulu Üyesi
Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Makina Mühendisliği Bölümü
2020 - Devam Ediyor
2020 - Devam EdiyorDistance Education Coordinator
Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Makina Mühendisliği Bölümü
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
2024
2024Exploiting Matrix Stiffness to Overcome Drug Resistance
Aydin H. B., ÖZÇELİKKALE A., ACAR A.
ACS BIOMATERIALS SCIENCE & ENGINEERING
, cilt.10, sa.8, ss.4682-4700, 2024 (SCI-Expanded)
2023
2023Predictive Design and Analysis of Drug Transport by MultiScale Computational Models Under Uncertainty
AKALIN A. A., DEDEKARGINOĞLU B., Choi S. R., Han B., ÖZÇELİKKALE A.
Pharmaceutical Research
, cilt.40, sa.2, ss.501-523, 2023 (SCI-Expanded)
2022
2022Migration and 3D Traction Force Measurements inside Compliant Microchannels
Afthinos A., Bera K., Chen J., Ozcelikkale A., Amitrano A., Choudhury M. I., et al.
NANO LETTERS
, cilt.22, sa.18, ss.7318-7327, 2022 (SCI-Expanded)
2022
2022Cytotoxic T Lymphocyte Activation Signals Modulate Cytoskeletal Dynamics and Mechanical Force Generation
Pathni A., Ozcelikkale A., Rey-Suarez I., Li L., Davis S., Rogers N., et al.
FRONTIERS IN IMMUNOLOGY
, cilt.13, 2022 (SCI-Expanded)
2020
2020An engineered pancreatic cancer model with intra-tumoral heterogeneity of driver mutations
Moon H., Ozcelikkale A., Yang Y., Elzey B. D., Konieczny S. F., Han B.
LAB ON A CHIP
, cilt.20, sa.20, ss.3720-3732, 2020 (SCI-Expanded)
2017
2017Differential response to doxorubicin in breast cancer subtypes simulated by a microfluidic tumor model
Ozcelikkale A., Shin K., Noe-Kim V., Elzey B. D., Dong Z., Zhang J., et al.
JOURNAL OF CONTROLLED RELEASE
, cilt.266, ss.129-139, 2017 (SCI-Expanded)
2017
2017Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices
Ozcelikkale A., Dutton J. C., Grinnell F., Han B.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
, cilt.14, sa.135, 2017 (SCI-Expanded)
2017
2017Enzyme-Induced Matrix Softening Regulates Hepatocarcinoma Cancer Cell Phenotypes
Liang Y., Clay N. E., Sullivan K. M., Leong J., Ozcelikkale A., Rich M. H., et al.
MACROMOLECULAR BIOSCIENCE
, cilt.17, sa.9, 2017 (SCI-Expanded)
2017
2017In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles
Ozcelikkale A., Moon H., Linnes M., Han B.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
, cilt.9, sa.5, 2017 (SCI-Expanded)
2017
2017Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling
Wan Q., ThucNhi TruongVo T. T., Steele H. E., Ozcelikkale A., Han B., Wang Y., et al.
SCIENTIFIC REPORTS
, cilt.7, 2017 (SCI-Expanded)
2016
2016Modulation of Matrix Softness and Interstitial Flow for 3D Cell Culture Using a Cell-Microenvironment-on-a-Chip System
Clay N. E., Shin K., Ozcelikkale A., Lee M. K., Rich M. H., Kim D. H., et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING
, cilt.2, sa.11, ss.1968-1975, 2016 (SCI-Expanded)
2016
2016Role of intracellular poroelasticity on freezing-induced deformation of cells in engineered tissues
Ghosh S., Ozcelikkale A., Dutton J. C., Han B.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
, cilt.13, sa.123, 2016 (SCI-Expanded)
2016
2016DNA Walker-Regulated Cancer Cell Growth Inhibition
Li F., Cha T., Pan J., Ozcelikkale A., Han B., Choi J. H.
CHEMBIOCHEM
, cilt.17, sa.12, ss.1138-1141, 2016 (SCI-Expanded)
2016
2016Thermal Destabilization of Collagen Matrix Hierarchical Structure by Freeze/Thaw
Ozcelikkale A., Han B.
PLOS ONE
, cilt.11, sa.1, 2016 (SCI-Expanded)
2014
2014Simulation of complex transport of nanoparticles around a tumor using tumor-microenvironment-on-chip
Kwak B., Ozcelikkale A., Shin C. S., Park K., Han B.
JOURNAL OF CONTROLLED RELEASE
, cilt.194, ss.157-167, 2014 (SCI-Expanded)
2013
2013Role of Cells in Freezing-Induced Cell-Fluid-Matrix Interactions Within Engineered Tissues
Seawright A., Ozcelikkale A., Dutton C., Han B.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
, cilt.135, sa.9, 2013 (SCI-Expanded)
2013
2013Multifaceted Transport Characteristics of Nanomedicine: Needs for Characterization in Dynamic Environment
Ozcelikkale A., Ghosh S., Han B.
MOLECULAR PHARMACEUTICS
, cilt.10, sa.6, ss.2111-2126, 2013 (SCI-Expanded)
2012
2012Least-squares spectral element solution of incompressible Navier-Stokes equations with adaptive refinement
Ozcelikkale A., SERT C.
JOURNAL OF COMPUTATIONAL PHYSICS
, cilt.231, sa.9, ss.3755-3769, 2012 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
2024
2024Tumor-Microenvironment-on-Chip Platform for Assessing Drug Response in 3D Dynamic Culture
Aydin H. B., Moon H., Han B., ÖZÇELİKKALE A., ACAR A.
Methods in molecular biology (Clifton, N.J.)
, cilt.2764, ss.265-278, 2024 (Scopus)
Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar
2023
2023Rapid prototyping of microfluidic co-culture platform based on a 3D printing workflow for systematic investigation of tumor stromal interactions
Dedekargınoğlu B., Ildız C., Acar A., Özçelikkale A.
The 2nd Microphysiological Systems World Summit, Berlin, Almanya, 26 - 30 Haziran 2023, cilt.11, sa.1, ss.200
2023
2023Parametric design and manufacturing of mammary carcinoma chip by stereolithography for simulating drug transport around the tumor
Fathi M., Dedekargınoğlu B., Akalın A. A., Özçelikkale A.
The 2nd Microphysiological Systems World Summit, Berlin, Almanya, 26 - 30 Haziran 2023, cilt.11, sa.1, ss.235-236
2023
2023Capillary pressure barriers for spatial confinement in organ-on-a-chip devices
Açıkgöz B. C., Dirmencioğlu U., Farahani S., Özçelikkale A., Yildirim E.
5th NOVEL FLUIDIC TECHNOLOGIES WORKSHOP WITH AN EMPHASIS ON TISSUE ENGINEERING, İzmir, Türkiye, 4 - 05 Mayıs 2023, ss.29-31
2022
2022Modeling and Characterization of Nanomedicine Transport within Tumor Microenvironment across Scales
Akalin A. A., Özçelikkale A.
16th Nanoscience and Nanotechnology Conference, Ankara, Türkiye, 5 - 08 Eylül 2022, ss.338
2021
2021Rapid Low-Cost Prototyping of Organ-on-Chip Platforms by 3D-Printed Microfluidics
Dedekargınoğlu B., Akalın A. A., Özçelikkale A.
3rd Annual European Organ-on-Chip Society Meeting, Uppsala, İsveç, 01 Temmuz 2021
2018
2018Regulation of Cytoskeletal Dynamics during T Cell Activation by Substrate Stiffness
Özçelikkale A., Upadhyaya A.
American Physical Society March Meeting, California, Amerika Birleşik Devletleri, 07 Mart 2018, ss.1
2012
2012NANOSCALE FLUID-STRUCTURE INTERACTIONS IN CYTOPLASM DURING FREEZING
Ozcelikkale A., Han B.
ASME International Mechanical Engineering Congress and Exposition, Texas, Amerika Birleşik Devletleri, 9 - 15 Kasım 2012, ss.711-716
2013
2013EFFECTS OF FREEZING ON COLLAGEN NANOSCALE STRUCTURE IN ENGINEERED TISSUES
Ozcelikkale A., Li Y., Xu X., Han B.
2nd ASME Global Congress on NanoEngineering for Medicine and Biology, Massachusetts, Amerika Birleşik Devletleri, 4 - 06 Şubat 2013, ss.29-30
2012
2012FUNCTIONAL IMAGING OF MATRIX STRUCTURE OF CRYOPRESERVED ENGINEERED TISSUES USING BACK-DIRECTIONAL GATED MESOSCOPIC IMAGING
Kim Y. L., Xu Z., Ozcelikkale A., Han B.
ASME Summer Bioengineering Conference (SBC), Fajardo, Porto Riko, 20 - 23 Haziran 2012, ss.259-260
2012
2012ROLE OF CELLS IN FREEZING-INDUCED CELL-FLUID MATRIX INTERACTIONS WITHIN ENGINEERED TISSUES
Seawright A., Ozcelikkale A., Dutton J. C., Han B.
ASME Summer Bioengineering Conference (SBC), Fajardo, Porto Riko, 20 - 23 Haziran 2012, ss.409-410
2010
2010h- and p-Adaptive Incompressible Flow Solutions on Cartesian Grids Using Least Squares Spectral Element Method
Özçelikkale A., Sert C.
5th European Conf. on CFD (ECCOMAS CFD), Lisbon, Portekiz, 14 - 17 Haziran 2010, ss.1-16
Desteklenen Projeler
2023 - 2024
2023 - 2024Stres Granül Bozulumunun Zaman Aşamalı Mikroskoskop ile Takibi
Yükseköğretim Kurumları Destekli Proje
MUYAN M. (Yürütücü), ÖZÇELİKKALE A., TURAN G.
Bilimsel Hakemlikler
Ağustos 2023
Ağustos 2023Türkiye Sağlık Enstitüleri Başkanlığı (TÜSEB) Araştırma Projesi
Orta Doğu Teknik Üniversitesi, Türkiye
Haziran 2023
Haziran 2023Yükseköğretim Kurumları Destekli Proje
BAP Araştırma Projesi, Orta Doğu Teknik Üniversitesi, Türkiye
Burslar
2020 - Devam Ediyor
2020 - Devam Ediyor2232 International Fellowship for Outstanding Researchers
TÜBİTAK
2010 - 2011
2010 - 2011Ross Graduate Fellowship
Üniversite
2008 - 2010
2008 - 2010