Metrikler
Yayın
26
Açık Erişim
3
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
2011 - 2015
2011 - 2015Bütünleşik Doktora
Université Henri Poincaré: Nancy I, Sciences, Chemistry, Fransa
2009 - 2011
2009 - 2011Yüksek Lisans
Université de Franche-Comté: Besançon, Chemistry, Fransa
2004 - 2009
2004 - 2009Lisans
Université de Franche-Comté: Besançon, Chemsitry, Fransa
Yaptığı Tezler
2015
2015Doktora
Molecular dynamics using a semiempirical quantum force field : development and applications to systems of biological interest
Université Henri Poincaré: Nancy I, Sciences, Chemistry
Yabancı Diller
B1 Orta
B1 OrtaAlmanca
C2 Ustalık
C2 UstalıkFransızca
A1 Başlangıç
A1 BaşlangıçTürkçe
C2 Ustalık
C2 Ustalıkİngilizce
Araştırma Alanları
Kimya
Fizikokimya
Hesapsal Kimya
Kuantum Mekaniği
Akademik Ünvanlar / Görevler
2018 - Devam Ediyor
2018 - Devam EdiyorDr. Öğr. Üyesi
Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü
2015 - 2017
2015 - 2017Araştırmacı
Technische Universitaet München, Life Sciences
Yönetilen Tezler
2022
2022Yüksek Lisans
Towards a general descriptor for the prediction of PKA
MARION A. (Danışman)
A.GÖÇER(Öğrenci)
2022
2022Yüksek Lisans
New protocol for scanning minor and major grooves along DNA to find best interaction mode with drug molecules
MARION A. (Danışman)
A.GÜLKAYA(Öğrenci)
Makaleler
Tümü (25)
SCI-E, SSCI, AHCI (24)
SCI-E, SSCI, AHCI, ESCI (25)
ESCI (1)
Scopus (25)
2025
20251. Phosphorylation of SNAP-25 at Ser187 is enhanced following its cleavage by Botulinum Neurotoxin Serotype A, promoting the dominant-negative effect of the resulting fragment
Koc D., EZGİN S., Kavakli E., Kota K. P., Sen E., Mahone C., et al.
PLOS Pathogens
, cilt.21, sa.10 October, 2025 (SCI-Expanded, Scopus)
2023
20232. Tetraphenyl-1,4-dioxin and Tetraphenyl-pyrane-4-one: Old Molecules, New Insights
SOYDAN M., Okyar B., ZORLU Y., MARION A., ÖZÇUBUKÇU S.
ACS OMEGA
, cilt.8, sa.22, ss.19656-19662, 2023 (SCI-Expanded, Scopus)
2022
20223. Activity-Based Photosensitizers with Optimized Triplet State Characteristics Toward Cancer Cell Selective and Image Guided Photodynamic Therapy
Kilic E., ELMAZOĞLU Z., Almammadov T., KEPİL D., Etienne T., MARION A., et al.
ACS Applied Bio Materials
, cilt.5, sa.6, ss.2754-2767, 2022 (ESCI, Scopus)
2022
20224. Peptide stapling by late-stage Suzuki-Miyaura cross-coupling
Gruss H., Feiner R. C., Mseya R., Schroeder D. C., Jewginski M., Mueller K. M., et al.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
, cilt.18, 2022 (SCI-Expanded, Scopus)
2022
20225. The Q41R mutation in the HCV-protease enhances the reactivity towards MAVS by suppressing non-reactive pathways
Zheng C., Schneider M., MARION A., Antes I.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
, cilt.24, sa.4, ss.2126-2138, 2022 (SCI-Expanded, Scopus)
2021
20216. Fullerene-Based Mimics of Biocatalysts Show Remarkable Activity and Modularity.
Gülseren G., Saylam A., Marion A., Özçubukçu S.
ACS applied materials & interfaces
, cilt.13, sa.38, ss.45854-45863, 2021 (SCI-Expanded, Scopus)
2021
20217. Peptidotriazolamers Inhibit Aβ(1-42) Oligomerization and Cross a Blood-Brain-Barrier Model.
Tonali N., Hericks L., Schroeder D. C., Kracker O., Krzemieniecki R., Kaffy J., et al.
ChemPlusChem
, cilt.86, ss.840-851, 2021 (SCI-Expanded, Scopus)
2021
20218. Tuning the Biological Activity of RGD Peptides with Halotryptophanst
Kemker I., Schroeder D. C., Feiner R. C., Mueller K. M., MARION A., Sewald N.
JOURNAL OF MEDICINAL CHEMISTRY
, cilt.64, sa.1, ss.586-601, 2021 (SCI-Expanded, Scopus)
2020
20209. Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors
Dultz G., Shimakami T., Schneider M., Murai K., Yamane D., MARION A., et al.
JOURNAL OF BIOLOGICAL CHEMISTRY
, cilt.295, sa.40, ss.13862-13874, 2020 (SCI-Expanded, Scopus)
2019
201910. Cyclization of RGD Peptides by Suzuki-Miyaura Cross-Coupling
Kemker I., Schnepel C., Schroeder D. C., MARION A., Sewald N.
JOURNAL OF MEDICINAL CHEMISTRY
, cilt.62, sa.16, ss.7417-7430, 2019 (SCI-Expanded, Scopus)
2019
201911. Actin stabilizing compounds show specific biological effects due to their binding mode
Wang S., Crevenna A. H., Ugur I., Marion A., Antes I., Kazmaier U., et al.
SCIENTIFIC REPORTS
, cilt.9, 2019 (SCI-Expanded, Scopus)
2019
201912. Predicting the bioactive conformations of macrocycles: a molecular dynamics-based docking procedure with DynaDock
Ugur I., Schroft M., Marion A., Glaser M., Antes I.
JOURNAL OF MOLECULAR MODELING
, cilt.25, sa.7, 2019 (SCI-Expanded, Scopus)
2019
201913. 1,4-Disubstituted 1H-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties
Schroeder D. C., Kracker O., Froehr T., Gora J., Jewginski M., Niess A., et al.
FRONTIERS IN CHEMISTRY
, cilt.7, 2019 (SCI-Expanded, Scopus)
2019
201914. Simple Tyrosine Derivatives Act as Low Molecular Weight Organogelators
Aykent G., Zeytun C., Marion A., Ozcubukcu S.
SCIENTIFIC REPORTS
, cilt.9, 2019 (SCI-Expanded, Scopus)
2019
201915. Semi-Empirical Born-Oppenheimer Molecular Dynamics (SEBOMD) within the Amber Biomolecular Package
Marion A., Gokcan H., Monard G.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
, cilt.59, sa.1, ss.206-214, 2019 (SCI-Expanded, Scopus)
2018
201816. Ca2+ binding induced sequential allosteric activation of sortase A: An example for ion-triggered conformational selection
Ugur I., Schatte M., Marion A., Glaser M., Boenitz-Dulat M., Antes I.
PLOS ONE
, cilt.13, sa.10, 2018 (SCI-Expanded, Scopus)
2018
201817. The low spin - high spin equilibrium in the S-2-state of the water oxidizing enzyme
Boussac A., Ugur I., Marion A., Sugiura M., Kaila V. R. I., Rutherford A. W.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
, cilt.1859, sa.5, ss.342-356, 2018 (SCI-Expanded, Scopus)
2018
201818. Activity of Topotecan toward the DNA/Topoisomerase I Complex: A Theoretical Rationalization
Bali S. K., MARION A., Ugur I., Dikmenli A. K., ÇATAK Ş., AVİYENTE V.
BIOCHEMISTRY
, cilt.57, sa.9, ss.1542-1551, 2018 (SCI-Expanded, Scopus)
2018
201819. 1,5-Disubstituted 1,2,3-Triazole-Containing Peptidotriazolamers: Design Principles for a Class of Versatile Peptidomimetics
Kracker O., Gora J., Krzciuk-Gula J., Marion A., Neumann B., Stammler H., et al.
CHEMISTRY-A EUROPEAN JOURNAL
, cilt.24, sa.4, ss.953-961, 2018 (SCI-Expanded, Scopus)
2018
201820. Amber-Compatible Parametrization Procedure for Peptide-like Compounds: Application to 1,4-and 1,5-Substituted Triazole-Based Peptidomimetics
Marion A., Gora J., Kracker O., Froehr T., Latajka R., Sewald N., et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
, cilt.58, sa.1, ss.90-110, 2018 (SCI-Expanded, Scopus)
2017
201721. Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ
Marion A., Groll M., Scharf D. H., Scherlach K., Glaser M., Sievers H., et al.
ACS CHEMICAL BIOLOGY
, cilt.12, sa.7, ss.1874-1882, 2017 (SCI-Expanded, Scopus)
2017
201722. DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles
Hoffmann T., Marion A., Antes I.
BMC STRUCTURAL BIOLOGY
, cilt.17, 2017 (SCI-Expanded, Scopus)
2015
201523. Why Does Asn71 Deamidate Faster Than Asn15 in the Enzyme Triosephosphate Isomerase? Answers from Microsecond Molecular Dynamics Simulation and QM/MM Free Energy Calculations
Ugur I., Marion A., Aviyente V., Monard G.
BIOCHEMISTRY
, cilt.54, sa.6, ss.1429-1439, 2015 (SCI-Expanded, Scopus)
2014
201424. Rationalization of the pK(a) Values of Alcohols and Thiols Using Atomic Charge Descriptors and Its Application to the Prediction of Amino Acid pK(a)'s
Ugur I., Marion A., Parant S., Jensen J. H., Monard G.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
, cilt.54, sa.8, ss.2200-2213, 2014 (SCI-Expanded, Scopus)
2014
201425. Water interactions with hydrophobic groups: Assessment and recalibration of semiempirical molecular orbital methods
Marion A., Monard G., Ruiz-Lopez M. F., Ingrosso F.
JOURNAL OF CHEMICAL PHYSICS
, cilt.141, sa.3, 2014 (SCI-Expanded, Scopus)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2018
20181. L-Tyr(tBu)-OH: An Outstanding Low Molecular Weight Organogelator
AYKENT G., ZEYTUN C., Marion A., ÖZÇUBUKÇU S.
4th Organic Chemistry Congress with Int. Participation, 4 - 07 Ekim 2018, (Özet Bildiri)
Ödüller
Eylül 2015
Eylül 2015Best PhD thesis award
Université De Lorraine (Université Henry Poincaré-Nancy I)