Dr. Yeşim Aydın Son is a medical scientist holding an M.D. and a Ph.D. in Genome Sciences and Technologies. She is a full-time faculty of METU Graduate School of Informatics since 2010 and promoted to the Assoc. Prof. position in the Bioinformatics Program in 2017. The main focus of her research is the modeling of chronic and complex diseases based on integrated genomic and clinical data. Her group has released a java based integrated software called METU-SNP, for genome-wide association and prioritization of SNP biomarkers through a novel AHP based algorithm. Her group continues to investigate the application of different data mining approaches to better associate genotyping data with diseases. They have proposed the SVM-ID3 hybrid method in 2014, which has been shown to outperform only the SVM method for the modeling of prostate cancer. Genomic Data-based modeling of Schizophrenia, Bipolar Disorder, Alzheimer’s and Parkinson’s disease, are among her ongoing projects.

2007 - 2009

Post Doctorate

City of Hope National Cancer Center, Beckman Research Institute, Molecular Medicine, United States Of America

2000 - 2006

Doctorate

University of Tennessee, Knoxville, Life Sciences, Graduate School of Genome Sciences And Technology, United States Of America

1993 - 1999

Doctorate

Hacettepe University, Tıp Fakültesi (Türkçe), Tıp Fakültesi, Turkey

2006

Doctorate

DIFFERENTIAL EXPRESSION OF SKINCANCER AND HAIR-FOLLICLE CYCLEREGULATED GENES IN TUMORSUSCEPTIBLE K14-AGOUTI MICE

University Of Tennessee, Knoxville, Genome Science And Technology

C1 Advanced

English

Computer Sciences, bioinformatics, Life Sciences, Bioinformatics, Molecular Biology and Genetics, Genetic Disorders, Genomics, Natural Sciences, Engineering and Technology

2017 - Continues

Associate Professor

Middle East Technical University, Graduate School Of Informatics, Medical Informatics

2010 - 2017

Assistant Professor

Middle East Technical University, Graduate School Of Informatics, Medical Informatics

2009 - 2010

Lecturer PhD

Middle East Technical University, Graduate School Of Informatics, Medical Informatics

2012 - Continues

Head of Department

Middle East Technical University, Graduate School of Informatics, Medical Informatics

2010 - 2012

Enstitü Yönetim Kurulu Üyesi

Middle East Technical University, Graduate School of Informatics, Medical Informatics

2010 - 2012

Program Koordinatörü

Middle East Technical University, Graduate School of Informatics, Medical Informatics

Postgraduate

Introduction to Medical Informatics

Postgraduate

Next Generation Sequence Analysis

Doctorate

MICROARRAY DATA ANALYSIS AND INFORMATICS

Postgraduate

CLINICAL BIOINFORMATICS

Postgraduate

PROTEIN AND DNA SEQUENCE ANALYSIS

Postgraduate

Futures Studies in Healthcare

2020

Doctorate

GENOME-WIDE SEQUENCE ANALYSIS OF HUMAN SPLICE ACCEPTOR REGIONS FOR MOTIF DISCOVERY

Aydin Son Y. (Consultant)

G.KARADUMAN(Student)

2019

Doctorate

Identification and investigation of metastasis specific miRNAs in breast cancer cells for miRNA replacement therapy

Ergene E., Aydin Son Y. (Co-Consultant)

E.EKENEL(Student)

2018

Doctorate

Optimization of weights and features in use of ahp for SNP prioritization

AYDIN SON Y. (Consultant)

A.YILMAZ(Student)

2018

Doctorate

Essential design components of genetic data enabled mobile personal health record systems

AYDIN SON Y. (Consultant) , AYDINOĞLU A. U. (Co-Consultant)

Ö.ÖZKAN(Student)

2017

Doctorate

Genomic modelling of bipolar disorders: Comparison of multifactor dimension reduction and classification-based data mining methods

AYDIN SON Y. (Consultant)

C.AÇIKEL(Student)

2017

Postgraduate

Investigation of the in vitro cytotoxic effects of boron on human hepatocellular carcinoma cell line, HepG2

AYDIN SON Y. (Co-Consultant) , GÜRAY N. T. (Co-Consultant)

H.ÇÖPOĞLU(Student)

2016

Postgraduate

Investigating the role of RNA-binding proteins (RBPs) in explaining differential gene expression in cancer

AYDIN SON Y. (Consultant)

A.LAFZI(Student)

2016

Postgraduate

Reconstruction of the temporal signaling network in salmonella infected human cells

TUNÇBAĞ N. (Co-Consultant) , AYDIN SON Y. (Co-Consultant)

G.BUDAK(Student)

2015

Postgraduate

A multi-layered graphical model of the relation among SNPs, genes, and pathways based on subgraph search

CAN T. (Co-Consultant) , AYDIN SON Y. (Co-Consultant)

G.ERSOY(Student)

2015

Postgraduate

Modeling the combined effect of RNA-binding proteins and micrornas in post-transcriptional regulation

AYDIN SON Y. (Consultant)

S.HAFEZQORANI(Student)

2014

Doctorate

A predictive model for type 2 diabetes mellitus based on genomic and phenotypic risk factors

AYDIN SON Y. (Consultant)

H.GÜL(Student)

2014

Postgraduate

Integration of metu-snp databases via rdf for pi-snp web service

AYDIN SON Y. (Consultant)

C.GEDİKOĞLU(Student)

2014

Doctorate

Single nucletide polymorphism (SNP) data integrated electronic health record (EHR) for personalized medicine

AYDIN SON Y. (Consultant)

T.Beyan(Student)

2014

Postgraduate

Cytokine polymorphism catalog (CytoCAT) for the analysis of phenotype associations

AYDIN SON Y. (Co-Consultant) , ACAR A. C. (Co-Consultant)

G.OĞUZ(Student)

2014

Postgraduate

Integration of METU-SNP databases via RDF for PI_SNP web service

AYDIN SON Y. (Co-Consultant) , Son Y.(Co-Consultant)

C.Gedikoğlu(Student)

2014

Postgraduate

Investigation of structural properties of methylated human promoter regions in terms of DNA helical rise

AYDIN SON Y. (Consultant)

B.YALDIZ(Student)

2014

Doctorate

Single nucleotide polymorphism (SNP) data integrated electronic health record (EHR) for personalized medicine

AYDIN SON Y. (Consultant)

T.BEYAN(Student)

2013

Postgraduate

A Method to improve the communication between information technology and healthcare professionals during mobile healthcare application development

AYDIN SON Y. (Co-Consultant) , Son Y.(Co-Consultant)

Y.Nasuh(Student)

2013

Postgraduate

Investigation of schizophrenia related genes and pathways through genome wide association studies

AYDIN SON Y. (Consultant)

H.ALPER(Student)

2013

Postgraduate

A framework for gene co-expression network analysis of lung cancer

CAN T. (Co-Consultant) , AYDIN SON Y. (Co-Consultant)

E.AKDEMİR(Student)

2013

Doctorate

A hybrid feature selection model for genome wide association studies

AYDIN SON Y. (Co-Consultant) , BAYKAL N. (Co-Consultant)

S.CAN(Student)

2012

Postgraduate

Investigation of human promoter CpG content and methylation profiles at different conservation levels

AYDIN SON Y. (Consultant)

B.DEMİRALAY(Student)

2012

Postgraduate

Predicting the disease of alzheimer (AD) with SNP biomarkers and clinical data based decision support system using data mining classification approaches

AYDIN SON Y. (Consultant)

O.ERDOĞAN(Student)

2011

Postgraduate

Determination of performance parameters for AHP based single nucleotide polymorphism (SNP) prioritization approach on Alzheimer’s disease data

AYDIN SON Y. (Consultant)

O.Kadıoğlu(Student)

2011

Doctorate

An integrative approach to structured SNP prioritization and representative snp selection for genome-wide association studies

AYDIN SON Y. (Consultant)

G.ÜSTÜNKAR(Student)

2011

Postgraduate

Determination of performance parameters for AHP based single nucleotide polymorphism (SNP) prioritization approach on alzheimers's disease data

AYDIN SON Y. (Consultant)

O.KADIOĞLU(Student)

2021

Kutlay A., AYDIN SON Y.

FRONTIERS IN MOLECULAR BIOSCIENCES, vol.8, 2021 (Journal Indexed in SCI)

2021

Şık A. S. , Aydınoğlu A. U. , Aydın Son Y.

HEALTH POLICY, vol.125, no.2, pp.203-212, 2021 (Journal Indexed in SCI)

2021

Acar A. C. , Er A. G. , Burduroğlu H. C. , Sülkü S. N. , Aydin Son Y. , Akin L., et al.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.51, no.1, pp.16-27, 2021 (Journal Indexed in SCI)

2020

Tombuloglu A., Copoglu H., AYDIN SON Y. , GÜRAY N. T.

Journal of Trace Elements in Medicine and Biology, vol.62, 2020 (Journal Indexed in SCI)

2016

Açikel C., Son Y. , Çelik C., Gül H.

Neuropsychiatric Disease and Treatment, vol.12, pp.2997-3004, 2016 (Journal Indexed in SCI Expanded)

2016

Hafezqorani S., Lafzi A., De Bruin R. G. , Van Zonneveld A. J. , Van Der Veer E. P. , Son Y. , et al.

NUCLEIC ACIDS RESEARCH, vol.44, 2016 (Journal Indexed in SCI)

2015

Budak G., Ozsoy O. E. , Son Y. , Can T. , Tunçbağ N.

FRONTIERS IN MICROBIOLOGY, vol.6, 2015 (Journal Indexed in SCI)

2015

Cengiz Han A., Aydin Son Y. , Çelik C., Recep T.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.25, pp.12-18, 2015 (Journal Indexed in SCI)

2015

AYDIN SON Y. , Batu E. D. , Demirkaya E., BİLGİNER Y., KASAPÇOPUR Ö., Unsal E., et al.

TURKISH JOURNAL OF PEDIATRICS, vol.57, no.4, pp.324-333, 2015 (Journal Indexed in SCI)

2014

Gul H., Aydin Son Y. , Acikel C.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.44, pp.946-982, 2014 (Journal Indexed in SCI)

2014

Beyan T., AYDIN SON Y.

Journal of Medical Internet Research, vol.16, no.8, 2014 (Journal Indexed in SCI Expanded)

2014

Beyan T., AYDIN SON Y.

Journal of Medical Internet Research, vol.16, no.8, 2014 (Journal Indexed in SCI Expanded)

2014

Yucebas S. C. , Aydin Son Y.

PLOS ONE, vol.9, 2014 (Journal Indexed in SCI)

2014

Beyan T., AYDIN SON Y.

Journal of Medical Internet Research, vol.16, no.7, 2014 (Journal Indexed in SCI Expanded)

2014

Beyan T., AYDIN SON Y.

Studies in Computational Intelligence, vol.546, pp.315-339, 2014 (Journal Indexed in SCI Expanded)

2012

Ustunkar G., Akyüz S., Weber G. W. , Friedrich C. M. , Aydin Son Y.

OPTIMIZATION LETTERS, vol.6, pp.1207-1218, 2012 (Journal Indexed in SCI)

2008

Jonathan M L., Edward J M., Trenton R S., Aydin Son Y. , Michael M., Bradley K Y.

DEVELOPMENTAL DYNAMICS, vol.237, no.8, pp.1960-1971, 2008 (Journal Indexed in SCI)

2005

Haycraft C., Banizs B., Aydin-Son Y. , Zhang Q., Michaud E., Yoder B.

PLOS GENETICS, vol.1, no.4, pp.480-488, 2005 (Journal Indexed in SCI)

2004

Balci S., Aypar E., Son Y. , Beksac M.

GENETIC COUNSELING, vol.15, no.3, pp.317-320, 2004 (Journal Indexed in SCI)

2002

Balci S., Kanra G., Aypar E., Son Y.

CLINICAL DYSMORPHOLOGY, vol.11, no.3, pp.171-173, 2002 (Journal Indexed in SCI)

1999

Balci S., Mavili M., Son Y. , Benli K., Erk Y.

ANNALS OF PLASTIC SURGERY, vol.43, no.4, pp.457-459, 1999 (Journal Indexed in SCI)

2012

AYDIN SON Y. , CAN T.

2012 7th International Symposium on Health Informatics and Bioinformatics, HIBIT 2012, 2012 (Refereed Journals of Other Institutions)

2011

Ustünkar G., Aydin Son Y.

Journal of integrative bioinformatics, vol.8, no.1, pp.187, 2011 (Refereed Journals of Other Institutions)

2018

AYDIN SON Y.

13. Tıbbi Genetik Kongresi, 7 - 11 November 2018

2018

Yazar Ö. F. , Yazar Untekin B., AYDIN SON Y.

11th International Conference on Health Informatics and Bioinformatics, October 2018, Belek, Antalya, Antalya, Turkey, 26 - 28 October 2018

2018

ŞIK A. S. , AYDIN SON Y. , AYDINOĞLU A. U. , SOYSAL E.

STS TURKEY 2018 Toplum için Bilim ve Teknoloji Çalışmaları Konferansı, Ankara, Turkey, 10 - 11 September 2018

2017

EKENEL E., ERGENE E., AYDIN SON Y.

19. Ulusal, Uluslararası Katılımlı Biyotoknoloji Kongresi, Eskişehir, Turkey, 1 - 03 December 2017

2017

YALDIZ B., AYDIN SON Y.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

YILMAZ A., AYDIN SON Y.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

ŞIK A. S. , AYDIN SON Y. , SOYSAL E., AYDINOĞLU A. U.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

BAHÇE KARADUMAN G., AYDIN SON Y.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

MİMAROĞLU ALTINAY B., AYDIN SON Y.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

ÖZKAN Ö., AYDIN SON Y. , AYDINOĞLU A. U. , YALÇIN A., DÖM H. A. , YALDIZ B., et al.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

DÖM H. A. , AYDIN SON Y.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2017

TOMBULOĞLU A. , ÇÖPOĞLU H., GÜRAY N. T. , AYDIN SON Y.

HIBIT 2017, Güzelyurt, Cyprus (Kktc), 28 - 30 June 2017

2015

AYDIN SON Y.

9th International Symposium on Health Informatics and BioinformaticsHIBIT 2015, Muğla, Turkey, 16 - 17 October 2015

2015

güngör b., EREN ÖZSOY Ö., AYDIN SON Y. , CAN T. , nurcan t.

23rd Annual International Conference on Intelligent Systems for Molecular Biology and the 14th European Conference on Computational Biology (ISMBECCB’2015), Dublin, Ireland, 10 - 14 July 2015

2015

ÖZKAN Ö., ARSEV UMUR A., AYDIN SON Y.

5th International Workshop on Infrastructures on Healthcare, 18 - 19 June 2015

2014

AYDIN SON Y. , YÜCEBAŞ S. C.

25th European Medical Informatics Conference (MIE), İstanbul, Turkey, 31 August - 03 September 2014, vol.205, pp.501-505

2014

Erdogan O., AYDIN SON Y.

25th European Medical Informatics Conference (MIE), İstanbul, Turkey, 31 August - 03 September 2014, vol.205, pp.511-515

2014

Gul H., AYDIN SON Y. , Acikel C.

25th European Medical Informatics Conference (MIE), İstanbul, Turkey, 31 August - 03 September 2014, vol.205, pp.1268

2013

Çelebi R., GÜMÜŞ Ö., AYDIN SON Y.

2013 8th International Symposium on Health Informatics and Bioinformatics, HIBIT 2013, Ankara, Turkey, 25 - 27 September 2013

2012

Hashemikhabir S., Ersoy G., Oguz G., Yaldiz B., Tuncel Y., Budak G., et al.

2012 7th International Symposium on Health Informatics and Bioinformatics, HIBIT 2012, Cappadocia, Turkey, 19 - 22 April 2012, pp.123-127

2012

Çarkacioǧlu L., Gedikoǧlu C., AYDIN SON Y.

2012 7th International Symposium on Health Informatics and Bioinformatics, HIBIT 2012, Cappadocia, Turkey, 19 - 22 April 2012, pp.114-117

2012

Kadioǧlu O., Üstünkar G., AYDIN SON Y.

2012 7th International Symposium on Health Informatics and Bioinformatics, HIBIT 2012, Cappadocia, Turkey, 19 - 22 April 2012, pp.7-10

2012

Ünsal Ş., Beyge M., AYDIN SON Y.

2012 7th International Symposium on Health Informatics and Bioinformatics, HIBIT 2012, Cappadocia, Turkey, 19 - 22 April 2012, pp.88-94

2010

Ustunkar G., AKYÜZ S., Weber G. -. , AYDIN SON Y.

Annual International Conference of the German-Operations-Research-Society (GOR), Neubiberg, Germany, 1 - 03 September 2010, pp.21-26

2019

AYDIN SON Y. , TAŞKIN B.

in: Uygulamalı Biyoenformatik, Münir Tunçer, Hilal Ay, Editor, Palme, pp.35-49, 2019

2014

Beyan T., Aydin Son Y.

in: Big Data and Internet of Things: A Roadmap for Smart Environments, N. Bessis and C. Dobre, Editor, Springer, London/Berlin , London, pp.315-339, 2014

2019

Özkan Ö., Aydin Son Y. , Aydinoğlu A. U.

Other, pp.1-17, 2019

2021 - Continues

Canlı sinir hücre hatlarında proteinprotein etkileşimlerinin incelenmesi için SPOCK1 geninin işaretlenmesi

Project Supported by Higher Education Institutions

AYDIN SON Y. (Executive) , DURSUN USAL T.

2017 - Continues

Hematopoetik Kök Hücre Hibernasyonunda Nöropeptid Y (NPY)´nin Rolünün İncelenmesi

Project Supported by Higher Education Institutions

YANIK T. (Executive) , ULUM B., UÇKAN ÇETİNKAYA P. D. D. , AERTS KAYA Y. D. D. F. , AYDIN SON Y.

2018 - 2021

Alzheimer Hastalığı'nın Erken ve Ayırıcı Tanısı için Genomik ve Klinik Bilgiye Dayalı in-Silico Model ve Genotiplendirme Kiti Geliştirilmesi ve Hastalarda Doğrulanması

TUBITAK Project

AYDIN SON Y. (Executive)

2018 - 2020

IC10 konsantrasyonunda Borik Asidin HepG2 hepatoselüler karsinoma hücre hattında harekete geçirdiği moleküler mekanizmaların farklı kimyasal koşullarla karşılaştırmalı olarak incelenmesi

Project Supported by Higher Education Institutions

AYDIN SON Y. (Executive) , TOMBULOĞLU A.

2011 - 2019

Metu-Snp: Snp Biyobelirteçlerinin Analizi Ve Hastalıklarla İlişkilendirilmesi Yazılımının Geliştirilmesi

Project Supported by Higher Education Institutions

AYDIN SON Y. (Executive) , Yılmaz A., ERDOĞAN O., Gedikoğlu C.

2014 - 2017

Farklı Nitelikteki Biyolojik Ağların Entegrasyonu ve Yerel Topolojik Özellik Vektörleri Tabanlı Karşılaştırılması

TUBITAK Project

CAN T. (Executive) , AYDIN SON Y.

2014 - 2016

Biyokimyasal sistemlerin stokastik simülasyon algoritmalarıyla yaratılması ve impuls içerecek şekilde genişletilmesi

Project Supported by Higher Education Institutions

PURUTÇUOĞLU GAZİ V. (Executive) , Tuncer G., SÜRÜN B., Yazıcı M., AYDIN SON Y. , UĞUR Ö.

2012 - Continues

Tıp Bilişimi Derneği

Board Member

2012 - 2014

Tıp Bilişimi Derneği

Secretary General

2016 - 2018

Scientific Consultancy

TÜSEB

2014 - 2016

Project Consultancy

AKGÜN

Total Citations (WOS): 785

h-index (WOS): 7