Assoc. Prof. TÜLİN YANIK

Education Information

1999 - 2003

Doctorate

The George Washington University, Fen-Ed Fak., United States Of America

Dissertations

2003

Doctorate

CATALASE ASSOCIATED PROTEINS IN PLANTS: A PROTECTIVE ASSOCIATION BETWEEN CATALASE AND ISOCITRATE LYASE

The George Washington University, Fen-Ed Fak.

Foreign Languages

B2 Upper Intermediate

English

Research Areas

Natural Sciences

Academic Titles / Tasks

2012 - Continues

Associate Professor

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology

Managerial Experience

2010 - 2013

Deputy Head of Department

Middle East Technical University, Faculty of Arts and Sciences, Department of Biology

Courses

Under Graduate

Endocrinology

Advising Theses

2020

Doctorate

Effects of maternal metabolic disorders on offspring antimicrobial peptides expression: change in antimicrobial defense system

YANIK T. (Consultant)

H.Taner(Student)

2019

Post Graduate

Analysis of candidate cocaine and amphetamine regulated transcript (CART) receptor genes: changes in ERK phosphorylation in N2a cells

YANIK T. (Consultant)

A.Özkılıç(Student)

2019

Post Graduate

ANALYSIS OF CANDIDATE COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT (CART) GENES:CHANGES IN ERK PHOSPHORYLATION IN N2a CELLS

YANIK T. (Co-Consultant) , SON Ç. D. (Co-Consultant)

A.ÖZKILIÇ(Student)

2019

Post Graduate

The effects of high cholesterol/high fat diet on endoplasmic reticulum stress and neuronal dysfunction in the hippocampus and cerebral cortex of APOE-/- MICE

YANIK T. (Consultant)

N.Mengi(Student)

2019

Doctorate

Assessment of the role of Neuropeptide Y in the regulation of hematopoietic stem cells

YANIK T. (Consultant)

B.Ulum(Student)

2019

Post Graduate

Investigation of cellular mechanisms of ser9leu proopiomelanocortin (POMC) mutation in neuronal cells

YANIK T. (Consultant)

M.VURAL(Student)

2017

Post Graduate

Impacts of olanzapine coupled with or without metformin administration on the expression of cannabinoid and melanocortin receptors in rats

YANIK T. (Consultant)

A.KEMAL(Student)

2014

Post Graduate

Effects of maternal high fat diet on hypothalamus vascularite of their offspring

PURUTÇUOĞLU GAZİ V. (Co-Consultant) , YANIK T. (Co-Consultant)

H.TANER(Student)

2014

Post Graduate

Effect of maternal high fat diet on hypothalamus vacularite of their offspring /

YANIK T. (Co-Consultant) , PURUTÇUOĞLU GAZİ V. (Co-Consultant)

H.Taner(Student)

2014

Post Graduate

Detection of hypothalamic neuropeptite levels involved in appetite regulation in aripiprazole treatment /

YANIK T. (Co-Consultant) , AKKAYA M. (Co-Consultant)

S.ÖZDEMİR(Student)

2014

Post Graduate

Investigation of the cellular mechanisims underlying the carboxypeptidase E mutation

YANIK T. (Consultant)

F.KAŞIKÇI(Student)

2014

Post Graduate

Effects of metformin on olanzapine induced weight gain in male wistar rats: The change of hypothalamic neurohormones involved in body weight regulation

YANIK T. (Consultant)

G.KURT(Student)

2012

Post Graduate

Determination of hypothalamic neuropeptide levels involved in appetite regulation in atypical antipsychotic drug, risperidone treatment

YANIK T. (Consultant)

C.KURŞUNGÖZ(Student)

2012

Post Graduate

Detecting g-protein coupled receptor interactions using enhanced green fluorescent protein reassembly

YANIK T. (Consultant)

G.KUMAŞ(Student)

2012

Post Graduate

Alterations of hypothalamic neuropeptides involved in food intake and appetite in olanzapine monotherapy

YANIK T. (Consultant)

D.SEZLEV(Student)

2012

Post Graduate

Manufacturing and analysis of thermal and chemical properties of potato starch-gelatin biofilms

YANIK T. (Consultant)

S.YILMAZ(Student)

2009

Post Graduate

Molecular characterization of strawberry by applying DNA fingerprinting technique using simple sequence repeats (SSRs) markers

YANIK T. (Consultant)

M.DERNAİKA(Student)

2009

Post Graduate

Effects of acrylamide and resveratrol on rabbit liver and kidney antioxidant enzymes

YANIK T. (Consultant)

Ç.KALIN(Student)

Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes

2021

Nanophase surface arrays on poly (lactic-co-glycolic acid) upregulate neural cell functions

MİMİROĞLU D. , YANIK T. , ERCAN B.

Journal of Biomedical Materials Research - Part A, 2021 (Journal Indexed in SCI Expanded)

2020

Neuropeptide Y is involved in the regulation of quiescence of hematopoietic stem cells

Ulum B., Mammadova A., ÖZYÜNCÜ Ö., Uckan-Cetinkaya D., YANIK T. , Aerts-Kaya F.

NEUROPEPTIDES, vol.80, 2020 (Journal Indexed in SCI)

2016

A human carboxypeptidase E/NF-alpha 1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice

Cheng Y., Cawley N. X. , YANIK T. , Murthy S. R. K. , Liu C., Kasikci F., et al.

TRANSLATIONAL PSYCHIATRY, vol.6, 2016 (Journal Indexed in SCI)

2016

Dysregulation of hypothalamic modulation in olanzapine treated male rats

Sezlev-Bilecen D., AK M., YANIK T.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, vol.71, pp.103-107, 2016 (Journal Indexed in SCI)

2015

Effects of risperidone treatment on the expression of hypothalamic neuropeptide in appetite regulation in Wistar rats

Kursungoz C., AK M., YANIK T.

BRAIN RESEARCH, vol.1596, pp.146-155, 2015 (Journal Indexed in SCI)

2013

Weight Gain in Risperidone Therapy Investigation of Peripheral Hypothalamic Neurohormone Levels in Psychotic Patients

YANIK T. , Kursungoz C., Sutcigil L., Ak M.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, vol.33, no.5, pp.608-613, 2013 (Journal Indexed in SCI)

2013

The investigation of leptin and hypothalamic neuropeptides role in first attack psychotic male patients: Olanzapine monotherapy

AK M., Sezlev D., Sutcigil L., Akarsu S., Ozgen F., YANIK T.

PSYCHONEUROENDOCRINOLOGY, vol.38, no.3, pp.341-347, 2013 (Journal Indexed in SCI)

2013

THE ROLE OF CENTRAL NEUROPEPTIDES IN WEIGHT GAIN CAUSED BY OLANZAPINE

Sezlev D., Ak M., YANIK T. , Kursungoz C., Akarsu S., Sutcigil L.

EUROPEAN PSYCHIATRY, vol.28, 2013 (Journal Indexed in SCI)

Refereed Congress / Symposium Publications in Proceedings

2019

The Effect of PDMS Nanophase Surface Topography on Cellular Proliferation

MİMİROĞLU D. , YANIK T. , ERCAN B.

24. Uluslararası Biyomedikal Bilim ve Teknoloji Sempozyumu (BIOMED), 17 - 20 October 2019

2018

The NPY-Y1 receptor for neuropeptide Y is highly expressed on hematopoietic stem cells from bone marrow and cord blood

Ulum B., Guney-Esken G., ÖZYÜNCÜ Ö., Uckan-Cetinkaya D., YANIK T. , Aerts-Kaya F.

Conference on Changing the Face of Modern Medicine - Stem Cell and Gene Therapy, Lausanne, Switzerland, 16 - 19 October 2018, vol.29

2015

Effects of metformin on olanzapine induced weight gain in wistar rats the change of hypothalamic neurohormones involved in body weight regulation

Ak M., Kurt G., YANIK T.

28th ECPN, 29 August - 11 September 2015

2013

Investigation of the cellular mechanisms underlying the carboxypeptidase E mutation

Kasikci F., Niamh C. X. , YANIK T. , Loh P. Y.

38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey And Alderney, 6 - 11 July 2013, vol.280, pp.203

2013

Atypical anti-psychotics and weight gain: risperidone induced male Wistar rats shows increased food intake and change levels of hypothalamic and circulating appetite related neurohormones

YANIK T. , Kursungoz C., Ak M.

38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey And Alderney, 6 - 11 July 2013, vol.280, pp.346-347

2013

Change of hypothalamic and peripheral levels of appetite related hypothalamic neurohormones in olanzapine treated male Wistar rats

YANIK T. , Sezlev D., Ak M.

38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey And Alderney, 6 - 11 July 2013, vol.280, pp.346

2010

Investigating of oral constraceptives effects on weight gaining mechanisms in polycystic ovary sendrome (PCOS) patients

YANIK T. , Sezlev D., Yildiz B. O.

9th International Meeting of the International-Society-for-the-Study-of-Xenobiotics(ISSX), İstanbul, Turkey, 4 - 08 September 2010, vol.42, pp.160-161

2010

Cocaine and Amphetamine Regulated Transcript (CART) blood levels increase after Risperidon treatment in psychotic disorder patients

YANIK T. , Kursungoz C., Sutcigil L., Ozgen F.

9th International Meeting of the International-Society-for-the-Study-of-Xenobiotics(ISSX), İstanbul, Turkey, 4 - 08 September 2010, vol.42, pp.159-160

2009

Risperidon (risperdal) therapy in schizophrenia: metabolic effects

YANIK T. , Kursungoz C., Sutcigil L., Ozgen F.

16th North American Regional ISSX Meeting, Maryland, United States Of America, 18 - 22 October 2009, vol.41, pp.186

Books & Book Chapters

2007

Techniques in neuropeptides processing, trafficking, and secretion

Cawley N. X. , YANIK T. , Loh Y. P. , Arnatuova I., Lou H., Patel N.

in: Neurochemistry Neuropeptide Techniques, Illana Gozes, Editor, Springer protocols, pp.67-96, 2007

Episodes in the Encyclopedia

2000

Encyclopedia of Life Sciences

Donaldson R. P. , Karyotou K., Assadi S., YANIK T.

Nature/McMillan Press, pp., 2000

Supported Projects

2017 - Continues

Hematopoetik Kök Hücre Hibernasyonunda Nöropeptid Y (NPY)´nin Rolünün İncelenmesi

Project Supported by Higher Education Institutions

YANIK T. (Executive) , ULUM B., UÇKAN ÇETİNKAYA P. D. D. , AERTS KAYA Y. D. D. F. , AYDIN SON Y.

2018 - 2020

ADAY CART RESEPTÖR GENLERİYLE ERK FOSFORİLASYONUNUN ANALİZİ

Project Supported by Higher Education Institutions

YANIK T. (Executive) , ÖZKILIÇ A.

2018 - 2019

ANNEYE AİT YÜKSEK YAĞLI BESİN TÜKETİMİNİN YAVRU MİKROBİYOTASI ÜZERİNDEKİ ETKİLERİ: ANNEDEN YAVRUYA OBEZOJENİK ÖZELLİKLERİN AKTARILMASI

Project Supported by Higher Education Institutions

YANIK T. (Executive) , TANER TEKER H.

2018 - 2019

G-alpha (i) proteinlerinin homodimerizasyonunun canlı hücrelerde tespiti

Project Supported by Higher Education Institutions

SON Ç. D. (Executive) , ZABCI S., ATAY Ö., İZGÜ K. F. , DOĞAN M. , YANIK T. , et al.

2017 - 2017

KAFETERYA DİYETİ SONRASI OBEZİTENİN HİPOTALAMUS ÜZERİNDEKİ DEĞİŞİKLİKLERİN İNCELENMESİ:BEYİN DAMARLARI

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2017 - 2017

ADAY CART RESEPTÖR GENLERİYLE ERK FOSFORİLASYONUNUN ANALİZİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2017 - 2017

YÜKSEK YAĞLI DİYET İLE DENEYSEL OBEZİTE OLUŞTURULAN SIÇANLARIN SEREBTAL KORTEKSLERİNDE MTOKONDRİ İLİŞKİLİ ER MEMBRANLARIN İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2017 - 2017

AŞIRI YAĞLI BESLENMEYE BAĞLI OBEZ SIÇANLARIN SEREBRAL KORTEKSLERİNDE ENDOPLAZMİK RETİKULUM STRESİNİN İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2017 - 2017

SIÇANLARDA PAROKSETİN VE FLUOKSETİNİN POMC VE NPY EKSPRESYON SEVİYELERİ ÜZERİNE ETKİSİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2017 - 2017

AMİLİN VE BATA AMİLOİD PROTEİNLERİNİN BEYİN DOKUSUNDA BİRLİKTE AGREGASYONUNUN ALZ-HEİMER PATHOLOJİSİNİN GELİŞİMİNDEKİ ROLÜNÜN ARAŞTIRILMASI

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2017 - 2017

NÖRON HÜCRELERİNDE ILE22MET PROOPİOMELANOCORTİN MUTASYONUNUN HÜCRESEL MEKANİZMASININ İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2016 - 2016

G-proteine Kenetli Reseptörlerin Birbirleri ile Olan Etkileşimlerinin Çift Moleküllü Floresan Birleşme (BiFC) ve Förster Rezonans Enerji Transferi (FRET) Metotları ile Araştırılması

Project Supported by Higher Education Institutions

SON Ç. D. (Executive) , ZABCI S., YANIK T. , KOCABIYIK S.

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2014 - 2016

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2015 - 2015

Isı şoku altında termofilik arkea'da (model: Thermoplasma volcanium) global gen anlatımındaki farklılaşmanın mikrodizin tekniği ile analizi

Project Supported by Higher Education Institutions

KOCABIYIK S. (Executive) , SON Ç. D. , YANIK T. , ZABCI S.

2014 - 2014

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2014 - 2014

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2014 - 2014

Kokain ve Amfetamin ile Regüle Edilen Transkript (CART)´le Etkileşip ERK fosforilasyonunu tetikleyen belirlenmiş on GPCR geninin qRT-PCR ile doğrulanması.

Project Supported by Higher Education Institutions

YANIK T. (Executive) , SON Ç. D. , KOCABIYIK S.

2012 - 2014

Atipik Antipsikotiklere Bağlı Kilo Almasında Santral Nöropeptitlerin Rolü Ve Tedavide Metforminin Etkinliği.

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2013 - 2013

KARBOKSİPEPTİDAZ E'NİN NÖROENDOKRİN SİSTEMDE HÜCRESEL MEKANİZMALARININ İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive) , KAŞIKÇI F.

2013 - 2013

ŞİZOFREN ETİYOLOJİSİNDE HİPOTOLAMİK ENERJİ METABOLİZMASIYLA İLGİLİ NÖROPEPTİTLERİN RÖLÜNÜN İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive) , ULUM B.

2013 - 2013

KARBOKSİPEPTİDAZ E (CPE) 'NİN SIÇANLARDA GEBELİK DÖNEMİNDEKİ GEN İFADELERİNİN İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive) , TEKER H. T.

2013 - 2013

POLİKİSTİK OVER SENDROMU BAĞLANTILI MET22 İLE PROOPİOMELAN OCORTİN (POMC) MUTASYONUNUN HÜCRESEL MEKANİZMALARININ İNCELENMESİ

Project Supported by Higher Education Institutions

YANIK T. (Executive) , KURT G.

2012 - 2013

Kokain Ve Amfetamin İle Regüle Edilen Transkript(cart) İle Etkileşip Erk Fosforilasyonunu Tetikleyen G-Proteine Kenetli Reseptörün Tespiti

Project Supported by Higher Education Institutions

YANIK T. (Executive) , kasap m., SON Ç. D. , KOCABIYIK S.

2011 - 2011

Polikistik Over Sendromunda Yeme Mekanizmalarını Düzenleyen Hipotalamik Hormonların Periferal Düzeylerinin Belirlenmesi

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2010 - 2010

Şizofren Hastaların Tedavinde Kullanılan Atipik Antipsikotik Olanzapine'nin Neden Olduğu Aşırı Kilo Alma Yan Etki Mekanizmalarının Nörohormon Gen Ve Protein Seviyelerinde İncelenmesi

Project Supported by Higher Education Institutions

YANIK T. (Executive)

2008 - 2008

Psikotik Bozukluklar (şizofreni) Ve Metabolik Sendrom: Psikotik Hastalarda Atipik Antipsikotiklerin Monoamine Nörotransmiter Genlerinin Açılım Düzeylerine Etkileri.