Education
1999 - 2003
1999 - 2003Doctorate
The George Washington University, Fen-Ed Fak., United States Of America
Dissertations
2003
2003Doctorate
CATALASE ASSOCIATED PROTEINS IN PLANTS: A PROTECTIVE ASSOCIATION BETWEEN CATALASE AND ISOCITRATE LYASE
The George Washington University, Fen-Ed Fak.
Foreign Languages
B2 Upper Intermediate
B2 Upper IntermediateEnglish
Research Areas
Natural Sciences
Academic Positions
2025 - Present
2025 - PresentProfessor
Middle East Technical University, Faculty Of Arts And Sciences, Department Of Biology
1993 - 2002
1993 - 2002Lecturer
Manisa Celal Bayar University, Faculty Of Arts And Scıences, Department Of Bıology
Managerial Experience
2010 - 2013
2010 - 2013Deputy Head of Department
Middle East Technical University, Faculty of Arts and Sciences, Department of Biology
Non Academic Experience
2007 - Present
2007 - PresentInstructor/Reader
METU, Instructor/Reader
2017 - 2018
2017 - 2018Akademik Ücretli İzin
National Institutes of Health, Maryland, ABD, Akademik Ücretli İzin
Supervised Theses
2022
2022Doctorate
The effect of nanoscale surface topography on adhesion, proliferation and protein expression of neuronal cells
YANIK T. (Advisor), ERCAN B. (Co-Advisor)
D.MİMİROĞLU(Student)
2022
2022Postgraduate
Investigation of effects of hyperlipidemia on IRE1a and insulin signaling pathway in the cerebral cortex of APOE-/- mice
YANIK T. (Advisor)
D.AK(Student)
Articles
2025
20251. Time-Dependent Effects of Metformin and Olanzapine on the Metabolic System
Kurt G., Durhan S. T., Ak M., YANIK T.
Pharmacopsychiatry
, vol.58, no.6, pp.285-292, 2025 (SCI-Expanded, Scopus)
2025
20252. Fluoxetine-induced weight change and the role of 5-HT2C receptor modulation in appetite regulation: a study in C57BL/6 mice
Altay H. O., Ak M., YANIK T.
FEBS OPEN BIO
, vol.15, pp.463, 2025 (SCI-Expanded, Scopus)
2025
20253. Exploring the role of growth hormone secretagogue receptor 1A (GHSR 1A) and γ-melanocyte stimulating hormone (γ-MSH) in obesity regulation
Durhan S. T., YANIK T.
FEBS OPEN BIO
, vol.15, pp.452, 2025 (SCI-Expanded, Scopus)
2025
20254. Pro-Opiomelanocortin and Melanocortin Receptor 3 and 4 Mutations in Genetic Obesity
YANIK T., Durhan S. T.
Biomolecules
, vol.15, no.2, 2025 (SCI-Expanded, Scopus)
2024
20245. Hyperlipidemia does not suppress mitophagy in the hippocampus. Science Communications World Wide.
Mengi Çamur N., Seker B., Kızıldag F., Onat U. I., Yanık T., Adams M.
Federation of European Neuroscience Societies , vol.1, no.1, pp.1-2, 2024 (Conference Book)
2024
20246. Synergistic effect of nanostructured topography and CNF incorporation into silk fibroin films enhances mouse neuroblastoma cell functions
MİMİROĞLU D., TUFAN Y., YANIK T., ERCAN B.
Surfaces and Interfaces
, vol.45, 2024 (SCI-Expanded, Scopus)
2023
20237. Neuroendocrinological and Clinical Aspects of Leptin.
Yanik T., Durhan S. T.
Mini reviews in medicinal chemistry
, 2023 (SCI-Expanded, Scopus)
2023
20238. Specific Functions of Melanocortin 3 Receptor (MC3R)
YANIK T., Durhan S. T.
Journal of clinical research in pediatric endocrinology
, vol.15, no.1, pp.1-6, 2023 (SCI-Expanded, Scopus, TRDizin)
2022
20229. Nanophase surface arrays on poly (lactic-co-glycolic acid) upregulate neural cell functions
Mimiroğlu D., Yanık T., Ercan B.
Journal of Biomedical Materials Research - Part A
, vol.110, no.1, pp.64-75, 2022 (SCI-Expanded, Scopus)
2020
202010. Neuropeptide Y is involved in the regulation of quiescence of hematopoietic stem cells
Ulum B., Mammadova A., ÖZYÜNCÜ Ö., Uckan-Cetinkaya D., YANIK T., Aerts-Kaya F.
NEUROPEPTIDES
, vol.80, 2020 (SCI-Expanded, Scopus)
2016
201611. A human carboxypeptidase E/NF-alpha 1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice
Cheng Y., Cawley N. X., YANIK T., Murthy S. R. K., Liu C., Kasikci F., et al.
TRANSLATIONAL PSYCHIATRY
, vol.6, 2016 (SCI-Expanded, Scopus)
2016
201612. Dysregulation of hypothalamic modulation in olanzapine treated male rats
Sezlev-Bilecen D., AK M., YANIK T.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
, vol.71, pp.103-107, 2016 (SCI-Expanded, Scopus)
2015
201513. Effects of risperidone treatment on the expression of hypothalamic neuropeptide in appetite regulation in Wistar rats
Kursungoz C., AK M., YANIK T.
BRAIN RESEARCH
, vol.1596, pp.146-155, 2015 (SCI-Expanded, Scopus)
2013
201314. Weight Gain in Risperidone Therapy Investigation of Peripheral Hypothalamic Neurohormone Levels in Psychotic Patients
YANIK T., Kursungoz C., Sutcigil L., Ak M.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
, vol.33, no.5, pp.608-613, 2013 (SCI-Expanded, Scopus)
2013
201315. The investigation of leptin and hypothalamic neuropeptides role in first attack psychotic male patients: Olanzapine monotherapy
AK M., Sezlev D., Sutcigil L., Akarsu S., Ozgen F., YANIK T.
PSYCHONEUROENDOCRINOLOGY
, vol.38, no.3, pp.341-347, 2013 (SCI-Expanded, Scopus)
2013
201316. THE ROLE OF CENTRAL NEUROPEPTIDES IN WEIGHT GAIN CAUSED BY OLANZAPINE
Sezlev D., Ak M., YANIK T., Kursungoz C., Akarsu S., Sutcigil L.
EUROPEAN PSYCHIATRY
, vol.28, 2013 (SCI-Expanded, SSCI, Scopus)
2010
201017. Systemic Delivery of Bioactive Glucagon-Like Peptide 1 after Adenoviral-Mediated Gene Transfer in the Murine Salivary Gland
Voutetakis A., Cotrim A. P., Rowzee A., Zheng C., Rathod T., Yanik T., et al.
ENDOCRINOLOGY
, vol.151, no.9, pp.4566-4572, 2010 (SCI-Expanded, Scopus)
2010
201018. Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density
Cawley N. X., Yanik T., Woronowicz A., Chang W., Marini J. C., Loh Y. P.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
, vol.299, no.2, 2010 (SCI-Expanded, Scopus)
2006
200619. The Leu34Phe proCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: A possible cause for obesity in humans
Yanik T., Dominguez G., Kuhar M., Del Giudice E., Loh Y.
ENDOCRINOLOGY
, vol.147, no.1, pp.39-43, 2006 (SCI-Expanded, Scopus)
2005
200520. A protective association between catalase and isocitrate lyase in peroxisomes
Yanik T., Donaldson R.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
, vol.435, no.2, pp.243-252, 2005 (SCI-Expanded, Scopus)
2004
200421. The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits
Cawley N., Zhou J., Hill J., Abebe D., Romboz S., Yanik T., et al.
ENDOCRINOLOGY
, vol.145, no.12, pp.5807-5819, 2004 (SCI-Expanded, Scopus)
Books
2007
20071. Techniques in neuropeptides processing, trafficking, and secretion
Cawley N. X., YANIK T., Loh Y. P., Arnatuova I., Lou H., Patel N.
in: Neurochemistry Neuropeptide Techniques, Illana Gozes, Editor, Springer protocols, pp.67-96, 2007
Episodes in the Encyclopedia
2008
20081. Plant Peroxisomes and Glyoxysomes
Yanik T.
John Wiley & Sons, West Sussex, UK , pp.doi.org/10.1002/9780470015902.a0001677.pub2, 2008
2000
20002. Encyclopedia of Life Sciences
Donaldson R. P., Karyotou K., Assadi S., YANIK T.
Nature/McMillan Press, pp., 2000
Other Publications
2024
20241. Hyperlipidemia Does not Supress Mitophagy in the Hippocampus
Mengi Çamur N., Seker B., Kızıldag F., Yanik T., Onat U. I., Adams M.
Presentation, pp.1, 2024
Funded Projects
2023 - Present
2023 - PresentAntidepresanlara bağlı kilo artışının serotonin 2C reseptörü ile ilişkisinin incelenmesi
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive), AK M., ALTAY H. O.
2017 - Present
2017 - PresentHematopoetik Kök Hücre Hibernasyonunda Nöropeptid Y (NPY)´nin Rolünün İncelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
YANIK T. (Executive), ULUM B., UÇKAN ÇETİNKAYA P. D. D., AERTS KAYA Y. D. D. F., AYDIN SON Y.
2023 - 2026
2023 - 2026
"Melanokortin 3 Reseptörünün (Mc3r) Hücre İçi Mekanizmaları Ve Trafiğinin İncelenmes
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
(Project Abstract)
YANIK T. (Executive)
2023 - 2025
2023 - 2025Melanokortin 3 Reseptörünün E3 ligaz proteini RNF11 ile etkileşiminin incelenmesi
Project Supported by Higher Education Institutions , BAP PhD
YANIK T. (Executive), BALKAN S. T.
2022 - 2024
2022 - 2024Melanokortin 3 reseptörünün MC3R hücresel mekanizmalarının incelenmesi
Project Supported by Higher Education Institutions , BAP Research Project
YANIK T. (Executive), GÜNBAŞ E. G., AKCASOY C.
2022 - 2024
2022 - 2024
Çocukluk çağı obezite Çift mutant MC3Rın büyüme hormon reseptörü ile etkileşiminin incelenmesi
Project Supported by Higher Education Institutions , BAP PhD
YANIK T. (Executive), BALKAN S. T.
2022 - 2023
2022 - 2023Hiperlipidemiye Bağlı İnflamasyonun Beyin Üzerine Etkileri ve PERK Yolağı Modülasyonu ile Hiperlipidemik Nöronal Disfonksiyonun Potansiyel Tedavisi
Project Supported by Higher Education Institutions , BAP PhD
YANIK T. (Executive), MENGİ N.
2021 - 2022
2021 - 2022Hiperlipidemiye Bağlı İnflamasyonun Beyin Üzerine Etkileri ve PERK Yolu Modülasyonu ile Hiperlipidemik Nöronal Disfonksiyonun Potansiyel Tedavisi
Project Supported by Higher Education Institutions , BAP PhD
YANIK T. (Executive), MENGİ N.
2021 - 2022
2021 - 2022Obez Anne Sıçanların Yavrularının Pankreatik Beta Hücrelerinin Transdönüşümünün İncelenmesi Transkriptom Analizi
Project Supported by Higher Education Institutions , BAP Research Project
YANIK T. (Executive)
2017 - 2017
2017 - 2017ADAY CART RESEPTÖR GENLERİYLE ERK FOSFORİLASYONUNUN ANALİZİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2017 - 2017
2017 - 2017
YÜKSEK YAĞLI DİYET İLE DENEYSEL OBEZİTE OLUŞTURULAN SIÇANLARIN SEREBTAL KORTEKSLERİNDE MTOKONDRİ İLİŞKİLİ ER MEMBRANLARIN İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2017 - 2017
2017 - 2017
AŞIRI YAĞLI BESLENMEYE BAĞLI OBEZ SIÇANLARIN SEREBRAL KORTEKSLERİNDE ENDOPLAZMİK RETİKULUM STRESİNİN İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2017 - 2017
2017 - 2017NÖRON HÜCRELERİNDE ILE22MET PROOPİOMELANOCORTİN MUTASYONUNUN HÜCRESEL MEKANİZMASININ İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2014 - 2016
2014 - 2016FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2014 - 2016
2014 - 2016FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2014 - 2014
2014 - 2014FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2014 - 2014
2014 - 2014FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2014 - 2014
2014 - 2014Kokain ve Amfetamin ile Regüle Edilen Transkript (CART)´le Etkileşip ERK fosforilasyonunu tetikleyen belirlenmiş on GPCR geninin qRT-PCR ile doğrulanması.
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive), SON Ç. D., KOCABIYIK S.
2012 - 2014
2012 - 2014Atipik Antipsikotiklere Bağlı Kilo Almasında Santral Nöropeptitlerin Rolü Ve Tedavide Metforminin Etkinliği.
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2013 - 2013
2013 - 2013KARBOKSİPEPTİDAZ E'NİN NÖROENDOKRİN SİSTEMDE HÜCRESEL MEKANİZMALARININ İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive), KAŞIKÇI F.
2013 - 2013
2013 - 2013ŞİZOFREN ETİYOLOJİSİNDE HİPOTOLAMİK ENERJİ METABOLİZMASIYLA İLGİLİ NÖROPEPTİTLERİN RÖLÜNÜN İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive), ULUM B.
2013 - 2013
2013 - 2013POLİKİSTİK OVER SENDROMU BAĞLANTILI MET22 İLE PROOPİOMELAN OCORTİN (POMC) MUTASYONUNUN HÜCRESEL MEKANİZMALARININ İNCELENMESİ
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive), KURT G.
2012 - 2013
2012 - 2013Kokain Ve Amfetamin İle Regüle Edilen Transkript(cart) İle Etkileşip Erk Fosforilasyonunu Tetikleyen G-Proteine Kenetli Reseptörün Tespiti
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive), kasap m., SON Ç. D., KOCABIYIK S.
2011 - 2011
2011 - 2011Polikistik Over Sendromunda Yeme Mekanizmalarını Düzenleyen Hipotalamik Hormonların Periferal Düzeylerinin Belirlenmesi
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
2010 - 2010
2010 - 2010
Şizofren Hastaların Tedavinde Kullanılan Atipik Antipsikotik Olanzapine'nin Neden Olduğu Aşırı Kilo Alma Yan Etki Mekanizmalarının Nörohormon Gen Ve Protein Seviyelerinde İncelenmesi
Project Supported by Higher Education Institutions , BAP Other
YANIK T. (Executive)
Peer Reviews in Scientific Publications
May 2025
May 2025Molecular Omics
SCI Journal
April 2025
April 2025OBESITY REVIEWS
SCI Journal
Scientific Project Refereeing
September 2021
September 2021TUBITAK Project
2219 - Yurt Dışı Doktora Sonrası Araştırma Burs Programı, Middle East Technical University, Turkey
September 2021
September 2021TUBITAK Project
2219 - Yurt Dışı Doktora Sonrası Araştırma Burs Programı, Middle East Technical University, Turkey
September 2021
September 2021TUBITAK Project
2219 - Yurt Dışı Doktora Sonrası Araştırma Burs Programı, Middle East Technical University, Turkey
Scientific Consultations
2022 - Present
2022 - PresentOther
TÜBİTAK
Middle East Technical University, Faculty of Arts and Sciences, Department of Biology, Turkey
2022 - 2022
2022 - 2022Scientific Consultancy
TÜBİTAK
Middle East Technical University, Faculty of Arts and Sciences, Department of Biology, Turkey
2021 - 2021
2021 - 2021Scientific Consultancy
TUBITAK
Middle East Technical University, Faculty of Arts and Sciences, Department of Biology, Turkey