Yayınlar & Eserler

Yayın Ağı
Makaleler 22
Tümü (22)
SCI-E, SSCI, AHCI (21)
SCI-E, SSCI, AHCI, ESCI (21)
Scopus (22)

1. Phosphorylation of SNAP-25 at Ser187 is enhanced following its cleavage by Botulinum Neurotoxin Serotype A, promoting the dominant-negative effect of the resulting fragment

Koc D., EZGİN S., Kavakli E., Kota K. P., Sen E., Mahone C., et al.
PLOS Pathogens , cilt.21, sa.10 October, 2025 (SCI-Expanded, Scopus) Creative Commons License identifier identifier

2. Astrocytes in Primary Familial Brain Calcification (PFBC): Emphasis on the Importance of Induced Pluripotent Stem Cell-Derived Human Astrocyte Models

Kavakli E., Gul N., BEGENTAŞ O. C., KİRİŞ E.
Advances in experimental medicine and biology , cilt.1479, ss.19-38, 2025 (Scopus) identifier identifier

3. Editorial: Studying rare diseases using induced pluripotent stem cell (iPSC)-based model systems

Francis K. R., Chen G., KİRİŞ E.
Frontiers in Cell and Developmental Biology , cilt.13, 2025 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

4. Tirbanibulin (KX2-391) analog KX2-361 inhibits botulinum neurotoxin serotype A mediated SNAP-25 cleavage in pre- and post-intoxication models in cells

Koc D., Ibis K., Besarat P., Banoğlu E., Kiriş E.
DRUG DEVELOPMENT RESEARCH , cilt.85, sa.6, 2024 (SCI-Expanded, Scopus) identifier identifier identifier

5. Generation and characterization of human induced pluripotent stem cell line METUi002-A from a patient with primary familial brain calcification (PFBC) carrying a heterozygous mutation (c.687dupT (p.Val230CysfsTer28)) in the SLC20A2 gene.

Begentas O. C., Koc D., Sendur N. K., Besarat P., Ezgin S., Temel M., et al.
Stem cell research , cilt.72, ss.103226, 2023 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

6. TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior.

Yanpallewar S., Tomassoni-Ardori F., Palko M. E., Hong Z., Kiris E., Becker J., et al.
Translational psychiatry , cilt.12, sa.1, ss.111, 2022 (SCI-Expanded, Scopus) identifier identifier identifier

7. Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity.

Sen E., Kota K. P., Panchal R. G., Bavari S., Kiris E.
Frontiers in pharmacology , cilt.12, ss.763950, 2021 (SCI-Expanded, Scopus) Creative Commons License Sürdürülebilir Kalkınma identifier identifier identifier

8. Generation and characterization of human induced pluripotent stem cell line METUi001-A from a 25-year-old male patient with relapsing-remitting multiple sclerosis

Begentaş O. C., Koc D., Yurtogullari S., Temel M., Akcali K. C., Demirkaya S., et al.
Stem Cell Research , cilt.53, 2021 (SCI-Expanded, Scopus) Creative Commons License Sürdürülebilir Kalkınma identifier identifier identifier

9. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model.

Konstantinović J., Kiris E., Kota K., Kugelman-Tonos J., Videnović M., Cazares L., et al.
Journal of medicinal chemistry , cilt.61, ss.1595-1608, 2018 (SCI-Expanded, Scopus) identifier identifier identifier

10. Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication.

Tsai Y., Kotiya A., Kiris E., Yang M., Bavari S., Tessarollo L., et al.
Proceedings of the National Academy of Sciences of the United States of America , cilt.114, 2017 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

11. Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner.

Choi M., Chung P., Song C., Miller H., Kiris E., Li Y., et al.
Biochimica et biophysica acta. General subjects , cilt.1861, ss.3456-3463, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

12. RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells.

Puverel S., Kiris E., Singh S., Klarmann K., Coppola V., Keller J., et al.
Oncotarget , cilt.7, ss.85109-85123, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

13. Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays.

Kiris E., Nuss J., Stanford S., Wanner L., Cazares L., Maestre M., et al.
PloS one , cilt.10, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

14. SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons.

Kiris E., Burnett J., Nuss J., Wanner L., Peyser B., Du H., et al.
Neurotoxicity research , cilt.27, ss.384-98, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

15. A high content imaging assay for identification of Botulinum neurotoxin inhibitors.

Kota K., Soloveva V., Wanner L., Gomba G., Kiris E., Panchal R., et al.
Journal of visualized experiments : JoVE , 2014 (SCI-Expanded, Scopus) identifier identifier identifier

16. TrkA in vivo function is negatively regulated by ubiquitination.

Kiris E., Wang T., Yanpallewar S., Dorsey S., Becker J., Bavari S., et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience , cilt.34, ss.4090-8, 2014 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

17. Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery.

Kiris E., Kota K., Burnett J., Soloveva V., Kane C., Bavari S.
Expert review of molecular diagnostics , cilt.14, ss.153-68, 2014 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

18. Recent advances in botulinum neurotoxin inhibitor development.

Kiris E., Burnett J., Kane C., Bavari S.
Current topics in medicinal chemistry , cilt.14, ss.2044-61, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

19. Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery.

Kiris E., Nuss J., Burnett J., Kota K., Koh D., Wanner L., et al.
Stem cell research , cilt.6, ss.195-205, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

20. Combinatorial Tau pseudophosphorylation: markedly different regulatory effects on microtubule assembly and dynamic instability than the sum of the individual parts.

Kiris E., Ventimiglia D., Sargin M., Gaylord M., Altinok A., Rose K., et al.
The Journal of biological chemistry , cilt.286, ss.14257-70, 2011 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

21. Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study.

Choi M., Raviv U., Miller H., Gaylord M., Kiris E., Ventimiglia D., et al.
Biophysical journal , cilt.97, ss.519-27, 2009 (SCI-Expanded, Scopus) Creative Commons License identifier identifier identifier

22. Model based dynamics analysis in live cell microtubule images.

Altinok A., Kiris E., Peck A., Feinstein S., Wilson L., Manjunath B., et al.
BMC cell biology , 2007 (SCI-Expanded, Scopus) identifier identifier identifier
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 10

1. Amyloid beta peptit oligomerlerinin (Aβ(1-42)) in vitro muamelesinin TrkB sinyali artırılmış kök hücre temelli kortikal nöronlar üzerindeki etkisinin doğal kortikal nöronlar ile kıyaslamalı olarak araştırılması

Beşarat P., EZGİN S., KİRİŞ E.
19. Ulusal Sinirbilim Kongresi, Online, Türkiye, 21 - 23 Kasım 2021, (Özet Bildiri)

2. Fare Kök Hücrelerinden Başkalaştırılmış Bazal Ön Beyin Kolinerjik Nöronlarda TrkA Sinyalinin Artırılmasının in vitro Alzheimer Hastalığını Nörodejeneratif Sürecine Karşı Etkisinin Kontrollere Kıyasla Araştırılması

EZGİN S., Beşarat P., KİRİŞ E.
19. Ulusal Sinirbilim Kongresi, Online, Türkiye, 21 - 23 Kasım 2021, (Özet Bildiri)

3. Kinase and Phosphatase Signaling Pathways Serve as Essential Host Factors for Botulinum Neurotoxins and are Targets for Pan-Serotype Drug Development

Nuss J., KİRİŞ E., Soloveva V., Duplantier A., Kane C.
Interagency Botulism Research Coordinating Committee Meeting, Fredericia, Danimarka, 25 Ekim 2015 - 28 Ekim 2016, (Özet Bildiri)

4. New Steroidal 4-aminoquinolines Antagonize BoNT/A in mES-MNs in Post-intoxication Model

Konstantinovic J. M., KİRİŞ E., Zlatovic M. V., Bavari S., Solaja B.
XXIV EFMC International Symposium on Medicinal Chemistry, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016, (Özet Bildiri)

5. The effect of human microtubule associated protein tau on the assembly structure of microtubules and its ionic strength dependence

Choi M. C., Raviv U., Miller H. P., Gaylord M., KİRİŞ E., Ventimiglia D., et al.
American Physical Society, APS March Meeting 2010, Portland, Amerika Birleşik Devletleri, 15 - 19 Mart 2010

6. Quantification of dynamic behavior of microtubules in living cells using novel computational methods

Altinok A., KİRİŞ E., Sargin M. E., Wilson L., Feinstein S. C., Manjunath B. S., et al.
38th Annual Meeting of Society for Neuroscience (SfN), Washington, Kiribati, 15 - 19 Kasım 2008

7. Novel tracking and analysis software for dynamic cell processes tau phosphorylation and the regulation of microtubule dynamics

KİRİŞ E., Gaylord M. R., Ventimiglia D., Altinok A., Sargin M. E., Rose K., et al.
16th Annual Research Symposium, Neuroscience Research Institute, University of Clifornia, Santa Barbara, Santa-Barbara, Honduras, 09 Mayıs 2008

8. Syncrotron X ray Diffraction Study on the Size Distribution and the Mechanical Stability of Microtubules by Microtubule Associated Protein MAP Tau

Choi M. C., Raviv U., Miller H. P., Gaylord M., KİRİŞ E., Ventimiglia D., et al.
American Physical Society (APS) Meeting, New Orleans, Amerika Birleşik Devletleri, 10 - 14 Mart 2008

9. Effects of combinatorial tau pseudophosphorylation upon its aggregation behavior in vitro

KİRİŞ E., Ventimiglia D., Gaylord M. R., Chen M., Medina H., Jordan M. A., et al.
18th Annual International Light Scattering Colloquium, Santa-Barbara, Honduras, 17 - 18 Ekim 2007

10. Tracing microtubules in live cell images

Sargin M. E., Altinok A., KİRİŞ E., Feinstein S. C., Wilson L., Rose K., et al.
2007 4TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING : MACRO TO NANO, VOLS 1-3, Darlington, Birleşik Krallık, 12 - 15 Nisan 2007, (Tam Metin Bildiri)
Kitaplar 4

1. Astrocytes in Primary Familial Brain Calcification (PFBC): Emphasis on the Importance of Induced Pluripotent Stem Cell-Derived Human Astrocyte Models

Kavaklı E., Gül N., BEGENTAŞ O. C., KİRİŞ E.
Advances in Experimental Medicine and Biology, Turksen Kursad, Editör, Springer, Cham, Cham, ss.1-20, 2025

2. Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis Patients

Begentaş O. C., Koç D., Kiriş E.
Methods in Molecular Biology, Induced Pluripotent Stem Cells and Human Disease, TURKSEN KURSAD, Editör, Humana Press, New York, ss.43-67, 2022 Creative Commons License Sürdürülebilir Kalkınma

3. Human-Induced Pluripotent Stem Cell–Based Models for Studying Sex-Specific Differences in Neurodegenerative Diseases

Kiriş E.
Advances in Experimental Medicine and Biology, Turksen,Kursad, Editör, Springer Nature, Zug, ss.57-88, 2021 Creative Commons License

4. Quantitative Analysis of MAP-Mediated Regulation of Microtubule Dynamic Instability In Vitro—Focus on Tau

Kiriş E., Ventimiglia D., Feinstein S. C.
METHODS IN CELL BIOLOGY, Leslie Wilson,John J. Correia, Editör, Elsevier Science, Oxford/Amsterdam , Massachusetts, ss.481-503, 2010
Metrikler

Yayın

37

Yayın (WoS)

21

Yayın (Scopus)

22

Atıf (WoS)

377

H-İndeks (WoS)

11

Atıf (Scopus)

390

H-İndeks (Scopus)

11

Atıf (Scholar)

584

H-İndeks (Scholar)

14

Proje

20

Tez Danışmanlığı

5

Açık Erişim

10
BM Sürdürülebilir Kalkınma Amaçları