SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons.

Kiris E., Burnett J., Nuss J., Wanner L., Peyser B., Du H., ...More

Neurotoxicity research, vol.27, pp.384-98, 2015 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 27
  • Publication Date: 2015
  • Doi Number: 10.1007/s12640-015-9526-z
  • Journal Name: Neurotoxicity research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.384-98
  • Keywords: Motor neurons, Human embryonic stem cells, Src inhibitors, Botulinum neurotoxins, Cell-based assay, Drug discovery, TYROSINE PHOSPHORYLATION, DIRECTED DIFFERENTIATION, CATALYTIC DOMAIN, RECEPTOR, SNAP-25, BINDING, METALLOPROTEASE, STABILIZATION, TECHNOLOGIES, MODULATION
  • Middle East Technical University Affiliated: No