Dr. Öğr. Üyesi AKTAN ALPSOY

1. Addressing the specific roles of histone modifications in transcriptional repression.

Hedehus L., Mas A. M., Alpsoy A., Armstrong R. L., Koche R., Tatar T., et al.

Nature communications , cilt.16, 2025 (SCI-Expanded, Scopus)

2. Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3

ALPSOY A., Ipsaro J. J., Skopelitis D., Pal S., Chung F. S., Carpenter S., et al.

CELL REPORTS , cilt.44, sa.11, 2025 (SCI-Expanded, Scopus)

3. MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer

Klingbeil O., Skopelitis D., Tonelli C., Yoshimoto T., ALPSOY A., Panepinto M. C., et al.

CANCER DISCOVERY , cilt.14, sa.12, ss.2471-2488, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

4. Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma

Maia-Silva D., Cunniff P. J., Schier A. C., Skopelitis D., Trousdell M. C., Moresco P., et al.

NATURE GENETICS , cilt.56, sa.7, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

5. Identification of SWI/SNF Subcomplex GBAF Presence, Intra-Complex Interactions, and Transcriptional Dynamics during Early Porcine Development

Innis S., ALPSOY A., Crodian J., Tseng Y., Dykhuizen E., Cabot B., et al.

ANIMALS , cilt.14, sa.5, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

6. I k B ζ is a dual-use coactivator of NFk B and POU transcription factors

ALPSOY A., Wu X. S., Pal S., Klingbeil O., Kumar P., Demerdash O. E., et al.

MOLECULAR CELL , cilt.84, sa.6, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

7. Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

Carcamo S., Nguyen C. B., Grossi E., Filipescu D., ALPSOY A., Dhiman A., et al.

CELL REPORTS , cilt.39, sa.1, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

8. Polycomb Paralog Chromodomain Inhibitors Active against Both CBX6 and CBX8**

Milosevich N., Wilson C. R., Brown T. M., ALPSOY A., Wang S., Connelly K. E., et al.

CHEMMEDCHEM , cilt.16, sa.19, ss.3027-3034, 2021 (SCI-Expanded, Scopus)

9. A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation

Wang S., ALPSOY A., Sood S., Ordonez-Rubiano S. C., Dhiman A., Sun Y., et al.

CHEMBIOCHEM , cilt.22, sa.13, ss.2335-2344, 2021 (SCI-Expanded, Scopus)

10. At the Crossroad of Gene Regulation and Genome Organization: Potential Roles for ATP-Dependent Chromatin Remodelers in the Regulation of CTCF-Mediated 3D Architecture

ALPSOY A., Sood S., Dykhuizen E. C.

BIOLOGY-BASEL , cilt.10, sa.4, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

11. BRD9 Is a Critical Regulator of Androgen Receptor Signaling and Prostate Cancer Progression

ALPSOY A., Utturkar S. M., Carter B. C., Dhiman A., Torregrosa-Allen S. E., Currie M. P., et al.

CANCER RESEARCH , cilt.81, sa.4, ss.820-833, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. Poly (I:C)- and doxorubicin-loaded magnetic dendrimeric nanoparticles affect the apoptosis-related gene expressions in MCF-7 cells

Khodadust R., Alpsoy A., Unsoy G., GÜNDÜZ U.

TURKISH JOURNAL OF BIOLOGY , cilt.44, sa.4, ss.133-144, 2020 (SCI-Expanded, Scopus, TRDizin) Sürdürülebilir Kalkınma

13. Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells

Cai B., Kim D., Akhand S., Sun Y., Cassell R. J., ALPSOY A., et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , cilt.141, sa.43, ss.17057-17061, 2019 (SCI-Expanded, Scopus)

14. A chemoproteomic portrait of the oncometabolite fumarate

Kulkarni R. A., Bak D. W., Wei D., Bergholtz S. E., Briney C. A., Shrimp J. H., et al.

NATURE CHEMICAL BIOLOGY , cilt.15, sa.4, ss.391-404, 2019 (SCI-Expanded, Scopus)

15. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association

Connelly K. E., Weaver T. M., ALPSOY A., Gu B. X., Musselman C. A., Dykhuizen E. C.

NUCLEIC ACIDS RESEARCH , cilt.47, sa.5, ss.2289-2305, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

16. **The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability**

Torres-Zelada E. F., Stephenson R. E., ALPSOY A., Anderson B. D., Swanson S. K., Florens L., et al.

JOURNAL OF CELL SCIENCE , cilt.132, sa.2, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

17. Autocrine Fibronectin Inhibits Breast Cancer Metastasis

Shinde A., Libring S., ALPSOY A., Abdullah A., Schaber J. A., Solorio L., et al.

MOLECULAR CANCER RESEARCH , cilt.16, sa.10, ss.1579-1589, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

18. A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling

Soto-Velasquez M., Hayes M. P., ALPSOY A., Dykhuizen E. C., Watts V. J.

MOLECULAR PHARMACOLOGY , cilt.94, sa.3, ss.963-972, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

19. Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes

ALPSOY A., Dykhuizen E. C.

JOURNAL OF BIOLOGICAL CHEMISTRY , cilt.293, sa.11, ss.3892-3903, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

20. Protein kinase D2 silencing reduced motility of doxorubicin-resistant MCF7 cells

Alpsoy A., GÜNDÜZ U.

TUMOR BIOLOGY , cilt.36, sa.6, ss.4417-4426, 2015 (SCI-Expanded, Scopus)

21. Etoposide resistance in MCF-7 breast cancer cell line is marked by multiple mechanisms

Alpsoy A., Yasa S., GÜNDÜZ U.

BIOMEDICINE & PHARMACOTHERAPY , cilt.68, sa.3, ss.351-355, 2014 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

Dr. Öğr. Üyesi AKTAN ALPSOY

Yayınlar & Eserler

1. Addressing the specific roles of histone modifications in transcriptional repression.

2. Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3

3. MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer

4. Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma

5. Identification of SWI/SNF Subcomplex GBAF Presence, Intra-Complex Interactions, and Transcriptional Dynamics during Early Porcine Development

6. I k B ζ is a dual-use coactivator of NFk B and POU transcription factors

7. Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

8. Polycomb Paralog Chromodomain Inhibitors Active against Both CBX6 and CBX8**

9. A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation

10. At the Crossroad of Gene Regulation and Genome Organization: Potential Roles for ATP-Dependent Chromatin Remodelers in the Regulation of CTCF-Mediated 3D Architecture

11. BRD9 Is a Critical Regulator of Androgen Receptor Signaling and Prostate Cancer Progression

12. Poly (I:C)- and doxorubicin-loaded magnetic dendrimeric nanoparticles affect the apoptosis-related gene expressions in MCF-7 cells

13. Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells

14. A chemoproteomic portrait of the oncometabolite fumarate

15. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association

16. **The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability**

17. Autocrine Fibronectin Inhibits Breast Cancer Metastasis

18. A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling

19. Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes

20. Protein kinase D2 silencing reduced motility of doxorubicin-resistant MCF7 cells

21. Etoposide resistance in MCF-7 breast cancer cell line is marked by multiple mechanisms

Yayın

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