Synergistic Mechanisms of Interactions between Myricetin or Taxifolin with α-Tocopherol in Oil-in-Water Emulsions

Bayram İ., Laze A., Decker E. A.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol.71, no.24, pp.9490-9500, 2023 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 71 Issue: 24
  • Publication Date: 2023
  • Doi Number: 10.1021/acs.jafc.3c01226
  • Journal Name: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Analytical Abstracts, Applied Science & Technology Source, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, Environment Index, Food Science & Technology Abstracts, Pollution Abstracts, Veterinary Science Database, DIALNET
  • Page Numbers: pp.9490-9500
  • Middle East Technical University Affiliated: No

Abstract

The antioxidant interactions between alpha-tocopheroland myricetinin stripped soybean oil-in-water emulsions at pH 4.0 and pH 7.0 wereanalyzed. At pH 7.0, alpha-tocopherol (alpha-TOC):myricetin (MYR)ratios of 2:1 and 1:1 yielded interaction indices of 3.00 and 3.63for lipid hydroperoxides and 2.44 and 3.00 for hexanal formation,indicating synergism. Myricetin's ability to regenerate oxidized alpha-tocopherol and slow its degradation was identified as thesynergism mechanism. Antagonism was observed at pH 4.0 due to highferric-reducing activity of myricetin in acidic environment. The interactionbetween alpha-tocopherol and taxifolin (TAX) was also investigateddue to structural similarities of myricetin and taxifolin. alpha-Tocopheroland taxifolin combinations exhibited antagonism at both pH 4.0 andpH 7.0. This was associated with taxifolin's inability to recycle alpha-tocopherol while still increasing the prooxidant activityof iron. The combination of alpha-tocopherol and myricetin was foundto be an excellent antioxidant strategy for oil-in-water emulsionsat pH values near neutrality.