FMRG verilerinin beyin ağları üzerine kurulu hiyerarşik temsili ve çözümlenmesi.

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Tezin Türü: Yüksek Lisans

Tezin Yürütüldüğü Kurum: Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Bilgisayar Mühendisliği Bölümü, Türkiye

Tezin Onay Tarihi: 2017

Tezin Dili: İngilizce

Öğrenci: Hazal Moğultay

Danışman: FATOŞ TUNAY YARMAN VURAL

Özet:

In this study, we propose a hierarchical network representation of human brain extracted from fMRI data. This representation consists of two levels. In the first level, we form a network among the voxels, smallest building block of fMRI data. In the second level, we define a set of supervoxels by partitioning the first level network into a set of subgraphs, which are assu med to represent homogeneous brain regions with respect to a predefined criteria. For this purpose, we develop a novel brain parcellation algorithm, called BrainParcel. As current literature tends to represent human brain as a graph, BrainParcel adopts this approach. The suggested algorithm partitions a brain network, called mesh network using a graph partitioning method. The supervoxels obtained at the output of BrainParcel form partitions of brain as an alternative to anatomical regions (AAL). Compared to AAL, supervoxels gather the linearly dependent voxels. As the next step, we form a mesh network among the supervoxels. Therefore, we represent fMRI data by two networks of different granularity. The first network is at voxel level, whereas the second is at supervoxel level. In order to test the representation power of this two level network, we suggest an ensemble learning architecture, called Cognitive Learner. The suggested ensemble learning method is used in brain decoding problem, where we classified the cognitive states. The results applied on an object recognition problem show that the suggested BrainParcel algorithm together with Cognitive Learner has a better representation power on brain decoding in terms of classification accuracy.