Akademik Veri Yönetim Sistemi
Tezin Türü: Yüksek Lisans
Tezin Yürütüldüğü Kurum: Orta Doğu Teknik Üniversitesi, Türkiye
Tezin Onay Tarihi: 2008
Tezin Dili: İngilizce
Öğrenci: Selin Kozanoğlu
Danışman: ALİ USANMAZ
Özet:Poly(N-vinylcaprolactam), PNVCL, is a nonionic, nontoxic, water soluble, thermally sensitive and biocompatible polymer. It contains hydrophilic carboxylic and amide groups with hydrophobic carbon-carbon backbone chain so its hydrolysis does not produce small amide compounds which are often not desired for biomedical applications. Moreover PNVCL possesses lower critical solution temperature, (LCST) in the range of physiological temperature (32-34 oC). These properties make the polymer suitable for use in some biotechnology applications such as implantation of artificial organs and tissues, purification of enzymes, proteins and living cells, and in drug release systems. In this study PNVCL was synthesized by free radical polymerization with solution technique. Polymerization was done at different temperatures for different time periods in an oil bath. The activation energy for polymerization was found from Arrhenius plot as 108.4 kJ/mol. Polymer was characterized by FT-IR, 1H-NMR and 13C-NMR, DSC, TGA and XRD techniques. FT-IR and NMR measurements confirmed that the polymerization proceeded through the vinyl group.