Akademik Veri Yönetim Sistemi
Tezin Türü: Doktora
Tezin Yürütüldüğü Kurum: Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Endüstri Mühendisliği Bölümü, Türkiye
Tezin Onay Tarihi: 2018
Öğrenci: ATIL KURT
Danışman: MERAL AZİZOĞLU
Özet:In this study, we consider the blood distribution system in Turkey and focus on Central Anatolian Regional Blood Center. Our problem differs from the classical distribution problems as it resides irradiation centers, urgent demands, vehicle availability and traveling time restrictions. In this study, we considered two problems. To address the first problem, we develop a mixed integer linear program with two objectives: maximizing the demand satisfaction and minimizing total time travelled by the vehicles. We propose two decomposition-based heuristic solution approaches. The results of our experiments have revealed that the model cannot solve even small sized instances in reasonable times; however, the heuristic solution approaches are appropriate for solving complex real life problems. Second problem proposes several demand satisfaction options by taking into account the irradiation centers, urgent demands, and product availability. To address the problem, we develop a mixed integer linear program with the objective of maximizing the weighted demand satisfaction, and propose a hybrid genetic algorithm. The results of our experiments have revealed that the model cannot solve even small sized instances in reasonable times; however, the hybrid genetic algorithm is appropriate for solving complex real life problems.