Antimicrobial properties of 3d printed silver nanowire/polylactide nanocomposites

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Tezin Türü: Yüksek Lisans

Tezin Yürütüldüğü Kurum: Orta Doğu Teknik Üniversitesi, Mühendislik Fakültesi, Metalurji ve Malzeme Mühendisliği Bölümü, Türkiye

Tezin Onay Tarihi: 2018

Öğrenci: İPEK BAYRAKTAR

Eş Danışman: HÜSNÜ EMRAH ÜNALAN, CEVDET KAYNAK

Özet:

Silver nanowire (Ag NW) loaded polylactide (PLA) nanocomposites were fabricated by simple solution mixing method and then 3D printed to obtain desired shapes. Morphological analysis, thermal analysis and antimicrobial performances of the fabricated nanocomposites with the addition of NWs were investigated. NWs showed good dispersion within the PLA matrix. Antibacterial properties of Ag NW/PLA nanocomposites were investigated against different standard bacterial strains of American Type Culture Collection (ATCC) using conventional microbiological methods. Ag NW based PLA nanocomposites were found to have high antibacterial effect against both Staphylococcus aureus ATCC#25923 (Gram positive bacteria) and Escherichia coli (ATCC#25922) (Gram negative bacteria). 4 wt. % Ag NW loaded nanocomposites were found to kill 100 % of Escherichia coli and Staphylococcus aureus bacteria in 2 hours and to continue its bactericidal effect for 24 hours against Escherichia coli and 8 hours against Staphylococcus aureus. Nanocomposites with higher Ag NW loadings showed better results yet small amount of Ag NW addition to PLA was found sufficient for nanocomposites to show reasonable antibacterial performance at low cost.