Atıf İçin Kopyala
Ayhan P., DEMİR A. G.
ADVANCED SYNTHESIS & CATALYSIS, cilt.353, sa.4, ss.624-629, 2011 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
353
Sayı:
4
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Basım Tarihi:
2011
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Doi Numarası:
10.1002/adsc.201000735
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Dergi Adı:
ADVANCED SYNTHESIS & CATALYSIS
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.624-629
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Anahtar Kelimeler:
amidation reaction, enzyme catalysis, hydroxamic acids, thiamine diphosphate-dependent enzyme, ALPHA-KETOGLUTARATE DEHYDROGENASE, HYDROXAMIC ACID PRODUCTION, N-ARYLHYDROXAMIC ACIDS, AROMATIC-COMPOUNDS, ARYL, REDUCTION, OXIDATION
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Orta Doğu Teknik Üniversitesi Adresli:
Evet
Özet
Benzaldehyde lyase from the Pseudomonas fluorescens catalyzes the reaction of aromatic aldehydes with nitroso compounds and furnishes N-arylhydroxamic acids in high yields. Aromatic aldehydes and benzoins are converted into enamine-carbanion-like intermediates prior to their reaction with nitroso compounds. The kinetic resolution of rac-2-hydroxy-1,2-diphenylethanones furnished (S)-benzoins and arylhydroxamic acids with high enantioselectivities and conversions.