CLINICAL BIOCHEMISTRY, vol.41, pp.1-9, 2008 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
paraoxonase, polymorphism, ischemic stroke, risk factors, genes, atherosclerosis, SERUM PARAOXONASE ACTIVITY, CORONARY-ARTERY-DISEASE, LOW-DENSITY-LIPOPROTEIN, MYOCARDIAL-INFARCTION, GENE POLYMORPHISMS, OXIDATIVE STRESS, VASCULAR-DISEASE, HEART-DISEASE, HUMPONA GENE, ARYLESTERASE
Middle East Technical University Affiliated:
Objectives: In recent years, importance of enzyme activity measurements, in addition to genotyping, in epidemiological studies relating paraoxonase 1 (PON1) and vascular disease was emphasized. This is the first report evaluating paraoxonase and arylesterase activities as risk factors for ischemic stroke. In addition, PON1 192Gln(Q)/Arg(R) and 55Leu(L)/Met(M) polymorphisms were also analyzed.