Conjugated polymer nanoparticle–MXene hybrid framework for sensitive electrochemical detection of serotonin
Journal of Electroanalytical Chemistry, cilt.1020, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 1020
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.jelechem.2026.120486
- Dergi Adı: Journal of Electroanalytical Chemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Chimica, Compendex, INSPEC
- Anahtar Kelimeler: Conjugated polymer, Electrochemical sensor, MXene composite, Serotonin detection
- Orta Doğu Teknik Üniversitesi Adresli: Evet
Özet
A sensitive and selective electrochemical sensor for serotonin (5-hydroxytryptamine, 5-HT) detection was developed by modifying a glassy carbon electrode (GCE) with a composite film of conjugated polymer nanoparticles, namely poly(benzenediamine-bis[(2-ethylhexyl)oxy]benzodithiophene) (p(BDBT) NPs), and Ti3C2Tx MXene nanosheets. The composite film was fabricated via drop-casting and characterized using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). The fabricated sensor showed a linear response to 5-HT over the concentration range of 0.10–15.0 μM, with a low detection limit (LOD) of 0.096 μM. The sensor demonstrated good selectivity for 5-HT in the presence of common interfering species and satisfactory recovery in spiked serum samples. Overall, the p(BDBT) NPs/MXene composite provides an effective platform for rapid and selective electrochemical determination of 5-HT.