GST isoenzymes in matched normal and neoplastic breast tissue

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OĞUZTÜZÜN S., Abu-Hijleh A., ÇOBAN T., Bulbul D., KILIÇ M., İŞCAN M., ...More

NEOPLASMA, vol.58, no.4, pp.304-310, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.4149/neo_2011_04_304
  • Journal Name: NEOPLASMA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.304-310
  • Middle East Technical University Affiliated: Yes


The potential to metabolize endogenous and exogenous substances may influence breast cancer development and tumor growth. Therefore we investigated GST activity and the protein expression of glutathione S-transferases (GSTs) isoenzymes known to be involved in the metabolism of endogenous and exogenous carcinogens in breast cancer tissue to obtain new information on their possible role in tumor progression.