Design of Carbon Nanotube Modified Conducting Polymer for Biosensing Applications

Ozdemir C., Tuncagil S., ODACI DEMİRKOL D., TİMUR S., TOPPARE L. K.

JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, cilt.48, sa.7, ss.503-508, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 7
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1080/10601325.2011.579804
  • Dergi Adı: JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.503-508
  • Anahtar Kelimeler: Electrochemical polymerization, conducting polymers, electrochemical biosensors, carbon nanotubes (CNT), ELECTROCHEMISTRY, IMMOBILIZATION, ELECTRODES, DISPERSION, COPOLYMER, PROTEINS
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

An electrochemical biosensor with improved performance was designed through the immobilization of glucose oxidase (GOx) onto conducting polymer of 4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine (SNS-NH2) modified with carbon nanotubes (CNTs). For the optimization and characterization of the biosensor, pH profile, enzyme loading, reproducibility, operational stability experiments were carried out. It was found that the use of CNTs in a biosensing system enhanced the biosensor response. The linear relation was observed using glucose as the substrate in the range of 0.1-2.0 mM and defined by the equation; y = 8.582x + 2.945 (R2= 0.994, where y and x stand for concentration in mM and current signal as A/cm2). Finally, proposed biosensor was applied for glucose detection in real samples.