CMOS Cell Sensors for Point-of-Care Diagnostics

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Adiguzel Y., KÜLAH H.

SENSORS, cilt.12, sa.8, ss.10042-10066, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 12 Sayı: 8
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3390/s120810042
  • Dergi Adı: SENSORS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.10042-10066
  • Anahtar Kelimeler: point-of-care diagnostics, CMOS, cell sensing, HUMAN CD4(+) CELLS, MICROELECTRODE ARRAY, ANALYTICAL PERFORMANCE, ELECTRICAL DETECTION, CONTACT IMAGER, REAL-TIME, CHIP, BIOSENSOR, IMPEDANCE, FLOW
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

The burden of health-care related services in a global era with continuously increasing population and inefficient dissipation of the resources requires effective solutions. From this perspective, point-of-care diagnostics is a demanded field in clinics. It is also necessary both for prompt diagnosis and for providing health services evenly throughout the population, including the rural districts. The requirements can only be fulfilled by technologies whose productivity has already been proven, such as complementary metal-oxide-semiconductors (CMOS). CMOS-based products can enable clinical tests in a fast, simple, safe, and reliable manner, with improved sensitivities. Portability due to diminished sensor dimensions and compactness of the test set-ups, along with low sample and power consumption, is another vital feature. CMOS-based sensors for cell studies have the potential to become essential counterparts of point-of-care diagnostics technologies. Hence, this review attempts to inform on the sensors fabricated with CMOS technology for point-of-care diagnostic studies, with a focus on CMOS image sensors and capacitance sensors for cell studies.