The facile synthesis of cyclopentanoid antibiotic kjellmanianone

Demir A., Tanyeli C., Gulbeyaz V., Akgul H.

TURKISH JOURNAL OF CHEMISTRY, vol.20, no.3, pp.244-248, 1996 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 3
  • Publication Date: 1996
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.244-248
  • Middle East Technical University Affiliated: Yes

Abstract

The synthesis of cyclopentanoid antibiotic Kjellmanianone is described in this study. The C-acylation of lithium enolates of 3-Methoxycyclopentenone by N-carbomethoxyimidazole or methylcyanoformate beta-ketoester, which when oxidized with Mn(III) acetate produces kjellmanianone in good yield.