Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes


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Yao C., Chen B. H. , Joehanes R., Otlu B., Zhang X., Liu C., ...Daha Fazla

CIRCULATION, cilt.131, sa.6, ss.536-746, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 131 Konu: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1161/circulationaha.114.010696
  • Dergi Adı: CIRCULATION
  • Sayfa Sayıları: ss.536-746

Özet

Background-Cardiovascular disease (CVD) reflects a highly coordinated complex of traits. Although genome-wide association studies have reported numerous single nucleotide polymorphisms (SNPs) to be associated with CVD, the role of most of these variants in disease processes remains unknown.