Photo-acoustic sensor based on an inexpensive piezoelectric film transducer and an amplitude-stabilized single-mode external cavity diode laser for in vitro measurements of glucose concentration

Bayrakli I., Erdogan Y. K.

OPTICS AND LASER TECHNOLOGY, vol.102, pp.180-183, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 102
  • Publication Date: 2018
  • Doi Number: 10.1016/j.optlastec.2017.12.034
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.180-183
  • Middle East Technical University Affiliated: Yes


The present paper focuses on development of a compact photo-acoustic sensor using inexpensive components for glucose analysis. An amplitude-stabilized wavelength-tunable single-mode external cavity diode laser operating around 1050 nm was realized and characterized for the use of laser beam as an excitation light source. In the established setup, a fine tuning range of 9 GHz was achieved. The glucose solution was obtained by diluting D-glucose in sterile water. The acoustic signal generated by the optical excitation was detected via a chip piezoelectric film transducer. A detection limit of 50 mM (900 mg/dl) was achieved. The device may be of great interest for its applications in medicine and health monitoring. The sensor is promising for non-invasive in vivo glucose measurements from interstitial fluid. (C) 2017 Elsevier Ltd. All rights reserved.