Recent chemo-/biosensor and bioimaging studies based on indole-decorated BODIPYs

Ozcan E., Kazan H. H., ÇOŞUT B.

LUMINESCENCE, cilt.35, sa.2, ss.168-177, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 35 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/bio.3719
  • Dergi Adı: LUMINESCENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Agricultural & Environmental Science Database, Analytical Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Communication Abstracts, EMBASE, INSPEC, MEDLINE, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.168-177
  • Anahtar Kelimeler: indole, BODIPY, sensing, biosensing, bioimaging, metal, anion, thiol, RATIOMETRIC FLUORESCENT-PROBE, HYDROGEN-SULFIDE, DYES SYNTHESIS, PHOTOPHYSICAL PROPERTIES, ENERGY-TRANSFER, CHEMOSENSOR, DERIVATIVES, CYANIDE, DESIGN, THIOPHENOLS
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

BODIPY is an important fluorophores due to its enhanced photophysical and chemical properties including outstanding thermal/photochemical stability, intense absorption/emission profiles, high photoluminescence quantum yield, and small Stokes' shifts. In addition to BODIPY, indole and its derivatives have recently gained attention because of their structural properties and particularly biological importance, therefore these molecules have been widely used in sensing and biosensing applications. Here, we focus on recent studies that reported the incorporation of indole-based BODIPY molecules as reporter molecules in sensing systems. We highlight the rationale for developing such systems and evaluate detection limits of the developed sensing platforms. Furthermore, we also review the application of indole-based BODIPY molecules in bioimaging studies. This article includes the evaluation of indole-based BODIPYs from synthesis to characterization and a comparison of the advantages and disadvantages of developed reporter systems, making it instructive for researchers in various disciplines for the design and development of similar systems.