ARKIVOC, pp.105-116, 2005 (SCI-Expanded)
Highly flexible and efficient syntheses of 1,2,3,5- substituted pyrroles starting from 2- propynyl-1,3- dicarbonyl compounds and amines are presented. TFA catalyzed formation of the pyrroles is suggested to proceed through sequential amination of the carbonyl compounds followed by regioselective 5- exo- dig cyclization of the enaminone intermediate and aromatization.