Realizing drug repositioning by adapting a recommendation system to handle the process


OZSOY M. G. , Ozyer T., POLAT F. , Alhajj R.

BMC BIOINFORMATICS, cilt.19, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Drug repositioning is the process of identifying new targets for known drugs. It can be used to overcome problems associated with traditional drug discovery by adapting existing drugs to treat new discovered diseases. Thus, it may reduce associated risk, cost and time required to identify and verify new drugs. Nowadays, drug repositioning has received more attention from industry and academia. To tackle this problem, researchers have applied many different computational methods and have used various features of drugs and diseases.