Unilateral deep brain stimulation suppresses alpha and beta oscillations in sensorimotor cortices

Abbasi O., Hirschmann J., Storzer L., ÖZKURT T. E., Elben S., Vesper J., ...Daha Fazla

NEUROIMAGE, cilt.174, ss.201-207, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 174
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.neuroimage.2018.03.026
  • Dergi Adı: NEUROIMAGE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.201-207
  • Anahtar Kelimeler: Neuronal oscillations, Parkinson's disease, Artefact rejection, Motor cortex, Beta band activity, Stimulation frequency, HIGH-FREQUENCY OSCILLATIONS, HUMAN SUBTHALAMIC NUCLEUS, ADVANCED PARKINSONS-DISEASE, GLOBUS PALLIDUS NETWORK, RESTING STATE, PATHOLOGICAL SYNCHRONIZATION, MOTOR-PERFORMANCE, MEG-DATA, EEG-DATA, MAGNETOENCEPHALOGRAPHY
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Deep brain stimulation (DBS) is an established therapy to treat motor symptoms in movement disorders such as Parkinson's disease (PD). The mechanisms leading to the high therapeutic effectiveness of DBS are poorly understood so far, but modulation of oscillatory activity is likely to play an important role. Thus, investigating the effect of DBS on cortical oscillatory activity can help clarifying the neurophysiological mechanisms of DBS. Here, we aimed at scrutinizing changes of cortical oscillatory activity by DBS at different frequencies using magneto-encephalography (MEG).