The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer

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Barry P., Vatsiou A., Spiteri I., Nichol D., Cresswell G. D., ACAR A., ...More

CLINICAL CANCER RESEARCH, vol.24, no.19, pp.4763-4770, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 19
  • Publication Date: 2018
  • Doi Number: 10.1158/1078-0432.ccr-17-3374
  • Journal Name: CLINICAL CANCER RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4763-4770
  • Middle East Technical University Affiliated: No

Abstract

Purpose: The most significant prognostic factor in early breast cancer is lymph node involvement. This stage between localized and systemic disease is key to understanding breast cancer progression; however, our knowledge of the evolution of lymph node malignant invasion remains limited, as most currently available data are derived from primary tumors.