Hybrid ventilation systems combine the superior properties of natural and mechanical ventilation systems to reduce energy consumption. In this study, hybrid ventilation simulations were performed for several cities in Turkey, which have different climate conditions. Matlab/Simulink was utilized to perform the simulations. The results of these simulations were compared with that of regular air conditioning units in terms of energy consumption. A hybrid ventilation system which shows the general behaviour of a fan-assisted natural ventilation system with temperature-based control and which provides both heating and cooling, is shown to be effective for four cities in Turkey that have different climate conditions. Results showed potential savings of around 25-30% when compared to a regular AC system.