Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction

Delikus, Rabia; Cakir, Emine; DEMİREL, NADİR; BALCI, METİN; KARATAŞ, BETÜL

doi:10.3906/kim-1504-80

Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction

Delikus R., Cakir E., DEMİREL N., BALCI M. , KARATAŞ B.

TURKISH JOURNAL OF CHEMISTRY, vol.40, no.2, pp.248-261, 2016 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 40 Issue: 2
Publication Date: 2016
Doi Number: 10.3906/kim-1504-80
Title of Journal : TURKISH JOURNAL OF CHEMISTRY
Page Numbers: pp.248-261

Abstract

Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetric Henry reaction. Various aromatic aldehydes were converted into chiral beta-nitro alcohols with high yields and moderate to acceptable enantioselectivities under the optimized reaction conditions.