Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction
TURKISH JOURNAL OF CHEMISTRY, vol.40, no.2, pp.248-261, 2016 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 40 Issue: 2
- Publication Date: 2016
- Doi Number: 10.3906/kim-1504-80
- Journal Name: TURKISH JOURNAL OF CHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.248-261
- Middle East Technical University Affiliated: No
Abstract
Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetric Henry reaction. Various aromatic aldehydes were converted into chiral beta-nitro alcohols with high yields and moderate to acceptable enantioselectivities under the optimized reaction conditions.