PLE catalyzed enantiomeric separation of (+/-)-2-furylcarbinols

Tanyeli C., Demir A., Arkin A., Akhmedov I.

ENANTIOMER, vol.2, no.6, pp.433-439, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 2 Issue: 6
  • Publication Date: 1997
  • Journal Name: ENANTIOMER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.433-439
  • Middle East Technical University Affiliated: Yes


O-Acetyl derivatives of (+/-)-2-furylcarbinols were resolved by PLE catalyzed hydrolysis to afford optically active 2-furylcarbinols in up to 98% e.e. that are valuable chiral building blocks in the synthesis of various biologically active compounds. Enantiomeric excess values were determined by using H-1-NMR and GC analysis of (S)-O-acetyllactyl ester derivatives of 2-furylcarbinols. They were also correlated with the Literature values.