PLE catalyzed enantiomeric separation of (+/-)-2-furylcarbinols


Tanyeli C. , Demir A. , Arkin A., Akhmedov I.

ENANTIOMER, vol.2, no.6, pp.433-439, 1997 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 2 Issue: 6
  • Publication Date: 1997
  • Title of Journal : ENANTIOMER
  • Page Numbers: pp.433-439

Abstract

O-Acetyl derivatives of (+/-)-2-furylcarbinols were resolved by PLE catalyzed hydrolysis to afford optically active 2-furylcarbinols in up to 98% e.e. that are valuable chiral building blocks in the synthesis of various biologically active compounds. Enantiomeric excess values were determined by using H-1-NMR and GC analysis of (S)-O-acetyllactyl ester derivatives of 2-furylcarbinols. They were also correlated with the Literature values.