PLE catalyzed enantiomeric separation of (+/-)-2-furylcarbinols

Tanyeli C., Demir A., Arkin A., Akhmedov I.

ENANTIOMER, cilt.2, sa.6, ss.433-439, 1997 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 6
  • Basım Tarihi: 1997
  • Dergi Adı: ENANTIOMER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.433-439
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

O-Acetyl derivatives of (+/-)-2-furylcarbinols were resolved by PLE catalyzed hydrolysis to afford optically active 2-furylcarbinols in up to 98% e.e. that are valuable chiral building blocks in the synthesis of various biologically active compounds. Enantiomeric excess values were determined by using H-1-NMR and GC analysis of (S)-O-acetyllactyl ester derivatives of 2-furylcarbinols. They were also correlated with the Literature values.