Salen Promoted Enantioselective Nazarov Cyclizations of Activated and Unactivated Dienones
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, cilt.135, sa.13, ss.4988-4991, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 135 Sayı: 13
- Basım Tarihi: 2013
- Doi Numarası: 10.1021/ja401908m
- Dergi Adı: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC), Current Chemical Reactions (CCR)
- Sayfa Sayıları: ss.4988-4991
- Orta Doğu Teknik Üniversitesi Adresli: Hayır
Özet
A novel class of chiral 5,5'-di(2,4,6-trialkyl)-aryl salen-metal complexes have been developed and shown to catalyze highly enantioselective Nazarov cyclization reactions, giving rise to cyclopentenoids in 90:10-98:2 er. Significantly, the catalysts also promote, for the first time, highly enantioselective Nazarov reactions of "unactivated" dienones, producing hydrindenone products having in place three contiguous chiral centers.