Akademik Veri Yönetim Sistemi
4th European Symposium on Biopolymers, Kusadasi, Türkiye, 2 - 04 Ekim 2007, cilt.269, ss.128-137
For any biomaterial placed into a biological medium, the surface properties of the material, such as porosity, crystallinity, presence and distribution of electrical charge and functional groups are very critical parameters that determine the acceptance or rejection of the material. Applications, especially tissue engineering require some surface modifications at the molecular level without disturbing the bulk properties of the implants in order to enhance the cell attachment on the material. An appropriate technique is the application of glow discharge plasma which employs no solvents, takes place at ambient temperatures, and alterations take place only at the surface by changing the surface chemistry along with surface free energy (SFE) and efficiency for cell-material interaction. In this study, poly(methyl methacrylate) (PMMA) film surfaces were modified with oxygen plasma. SFE and its dispersive and polar (acidic-basic) components of the modified surfaces were calculated by means of several theoretical approaches including geometric mean, harmonic mean and acid-base equations. The relation between SFE and its dispersive and polar components and cell attachment on surfaces were studied. The highest 3T3 cell attachment was obtained for the surface with the total SFE of 61.77 mJ/m(2) and polar component of 50.91 mJ/m(2) according to Geometric mean. The total SFE of this surface was calculated to be 61.06 mJ/m(2) and the polar component as 40.96 mJ/m(2) using the Harmonic mean method.