Temperature dependence of the phospholipids bilayers stability, studied by FTIR spectroscopy

Severcan F., Agheorghiesei C., Dorohoi D.

REVISTA DE CHIMIE, vol.59, no.3, pp.356-359, 2008 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 3
  • Publication Date: 2008
  • Journal Name: REVISTA DE CHIMIE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.356-359


The temperature induced modifications in the lipid bilayers in water were studied by using 2D-FTIR Correlation Spectroscopy. The spectral range analysed in this paper corresponds to symmetric and asymmetric stretching vibrations of the -CH2 groups from the acyl chains of DPPC. Autocorrelation peaks at 2916 cm(-1) and 2848.5 cm(-1) and asynchrone modifications in the spectral ranges 2916-3000 cm(-1) and 2848-3000 cm(-1) were evidenced. The revealed modifications indicate changes in the conformers of the hydrocarbon chains in the phase transition from the gel to liquid crystalline phases, as well as the variations in the concentration of the two phases with temperature increasing.