Synthesis of ferrocenyl pyrazoles by the reaction of 3-ferrocenylpropynal with hydrazinium salts
JOURNAL OF ORGANOMETALLIC CHEMISTRY, cilt.693, sa.1, ss.145-154, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 693 Sayı: 1
- Basım Tarihi: 2008
- Doi Numarası: 10.1016/j.jorganchem.2007.10.035
- Dergi Adı: JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.145-154
- Anahtar Kelimeler: ferrocene, pyrazole, hydrazine, propynal, cyclization, condensation, ESTROGEN-RECEPTOR MODULATORS, ONE-POT SYNTHESIS, ACTIVITY IN-VITRO, REGIOSELECTIVE SYNTHESIS, ANTIMALARIAL ACTIVITY, ORGANOMETALLIC ANALOG, DIACETYLENIC KETONES, EFFICIENT SYNTHESIS, CRYSTAL-STRUCTURES, BUILDING-BLOCK
- Orta Doğu Teknik Üniversitesi Adresli: Evet
Özet
Synthesis of ferrocenyl-substituted pyrazoles via the reaction between 3-ferrocenylpropynal and hydrazinium salts is described. Depending upon the substitution pattern of hydrazine derivative, the reaction affords 1-alkyl/aryl-5-ferrocenylpyrazoles and/or 1-alkyl/aryl-3-ferrocenylpyrazoles. Structures of 5-ferrocenyl-1-phenyl-1H-pyrazole, 1-benzyl-5-ferrocenyl-1H-pyrazole and 2-(3-ferrocenylpyrazol-1-yl)ethanol were identified by X-ray crystallography. (c) 2007 Elsevier B.V. All rights reserved.