Learning functional properties of proteins with language models


Unsal S., Atas H., ALBAYRAK M., TURHAN K., Acar A. C., DOĞAN T.

NATURE MACHINE INTELLIGENCE, vol.4, no.3, pp.227-245, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.1038/s42256-022-00457-9
  • Journal Name: NATURE MACHINE INTELLIGENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.227-245
  • Middle East Technical University Affiliated: Yes

Abstract

Deep learning methods have in recent years shown promising results in characterizing proteins and extracting complex sequence-structure-function relationships. This Analysis describes a benchmarking study to compare the performances and advantages of recent deep learning approaches in a range of protein prediction tasks.