Manganese(III) acetate-mediated oxidative coupling of phenylhydrazines with furan and thiophene: a novel method for hetero biaryl coupling

Demir A., Reis O., Emrullahoglu M.

TETRAHEDRON, vol.58, no.40, pp.8055-8058, 2002 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 40
  • Publication Date: 2002
  • Doi Number: 10.1016/s0040-4020(02)01001-3
  • Journal Name: TETRAHEDRON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.8055-8058
  • Middle East Technical University Affiliated: Yes

Abstract

A convenient new method for the arylation of furan and thiophene with arylhydrazine and manganese(III) acetate is described. Oxidation of arylhydrazines with Mn(III) acetate in furan or thiophene affords the corresponding 2-aryl-substituted furans and thiophenes in good yield using commercially available materials; access to 2-substituted heterobiaryls works selectively, and coupling occurs with loss of the hydrazine moiety. (C) 2002 Elsevier Science Ltd. All rights reserved.