Some fields in honey bee research require oral administration of substances to bees individually. This paper describes a relatively easy, practical, and reversible method for harnessing and oral feeding of honey bees. Individual bees are immobilized on a piece of balsa wood stick with two pins crossed on the junction between thorax and abdomen. Restrained bees can then easily be fed with a specific amount of chemical or pathogen in sucrose solution by inducing proboscis extension reflex. Important aspects and possible drawbacks of the method are also discussed.