Arterial stenosis leads to serious health problems such as stroke and heart attack. For a clinician, it is of critical importance to diagnose the stenosis at an early stage to prevent serious damage. Peripheral artery diseases observed in the arms and legs can be a sign of serious cardiovascular disorders. For a stenosed artery, turbulence is observed downstream of constriction exit. Turbulent flow generates sound and vibration on artery wall. Vibro-acoustic radiation propagates through surrounding tissues and reaches skin surface. In this study, skin surface response of thigh due to acoustic generation from a stenosed femoral artery is investigated which may provide important information for diagnostic purposes. Human thigh is modelled using commercial finite element analysis software ADINA. Modal analyses are performed for thigh model. Realistic material properties and model geometry are employed. Acoustic generation due to arterial stenosis is modelled using empirical relations provided in literature. Harmonic acoustic pressures are applied on the inner surface of the artery wall. Radial velocity response and pressure response on thigh skin surface are obtained by considering different stenosis degrees and different stenosis locations. Results indicate that increasing stenosis degree leads to an increase in amplitudes of harmonic responses. Highest radial velocity and pressure amplitudes are obtained at locations closest to the arterial stenosis. Low frequency response between 0-50 Hz is found to be more useful to obtain information about the location of the stenosis.