Vancomycin containing PLLA/beta-TCP controls experimental osteomyelitis in vivo

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Kankilic B., BİLGİÇ E., KORKUSUZ P., KORKUSUZ F.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, cilt.9, 2014 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 9
• Basım Tarihi: 2014
• Doi Numarası: 10.1186/s13018-014-0114-3
• Dergi Adı: JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Anahtar Kelimeler: Bone, Osteomyelitis, Drug delivery, Rat, Vancomycin, PLLA, beta-TCP, MRSA, Infection, TRICALCIUM PHOSPHATE COMPOSITES, POLY-EPSILON-CAPROLACTONE, IMPLANTS, RELEASE, MODEL, VITRO, INFECTIONS, KINETICS, DELIVERY, RATS
• Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Background: Implant-related osteomyelitis (IRO) is recently controlled with local antibiotic delivery systems to overcome conventional therapy disadvantages. In vivo evaluation of such systems is however too little.