Structural characterization of recombinant bovine Go alpha by spectroscopy and homology modeling

MEGA TİBER P., Orun O., Nacar C., Sezerman U. O., Severcan F., Severcan M., ...More

SPECTROSCOPY-BIOMEDICAL APPLICATIONS, vol.26, pp.213-229, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26
  • Publication Date: 2011
  • Doi Number: 10.3233/spe-2011-0543
  • Journal Name: SPECTROSCOPY-BIOMEDICAL APPLICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.213-229
  • Middle East Technical University Affiliated: Yes

Abstract

Go, a member of heterotrimeric guanine nucleotide-binding proteins, is the most abundant form of G protein in the central and peripheral nervous systems. Go alpha has a significant role in neuronal development and function but its signal transduction mechanism remains to be clarified.