Results of a recent bridge inventory evaluation indicated that about 50% of Turkish highway bridges have more than 30 degrees of skew angle and can be classified as irregular bridges. During the recent major earthquake in Turkey, multisimple-span bridges with continuous decks and link slabs performed well even though these bridges were in the vicinity of the fault line. This study aims to evaluate the improvements in seismic response of skew bridges in terms of forces and displacements when link slabs are added as a retrofit tool. A series of elastic dynamic analyses and nonlinear time history analyses were conducted to investigate the seismic response of various standard highway bridges with different span lengths and skew angles. A new reinforcement design for edge zones of link slabs is proposed for bridges located in high seismic zones. In practice, link slabs can be implemented easily during a regular redecking of a bridge.