The investigation of brain growth retardation in rat fetus
BIOCHEMICAL ARCHIVES, cilt.15, sa.1, ss.69-74, 1999 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 1
- Basım Tarihi: 1999
- Dergi Adı: BIOCHEMICAL ARCHIVES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.69-74
- Orta Doğu Teknik Üniversitesi Adresli: Hayır
Özet
We have investigated the activation of the mitogen-activated protein kinases ERK1 and ERK2 in fetal rat brain following induction of ischemia. This treatment rapidly increases the phosphorylation of MAP kinase levels after induction appears to reach a maximum at 2 hrs recirculation time. The ischemic effect on fetal brain might lead to mitogen-activated protein kinase activation and subsequent protein phosphorylation.