Transition metal compound mediated reduction of alpha-amino acids to 1,2-amino alcohols with NaBH4 in water
TURKISH JOURNAL OF CHEMISTRY, vol.23, no.2, pp.123-126, 1999 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 23 Issue: 2
- Publication Date: 1999
- Journal Name: TURKISH JOURNAL OF CHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.123-126
- Middle East Technical University Affiliated: Yes
Abstract
A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.