Reaction of 4-methoxy-4-(1-methylethenyl)-2-cyclobutenone derivatives with 2-lithiopropene and alpha-lithiostyrene: synthesis of eight-membered ring carbocycles

Zora, METİN; Koyuncu, I; Yucel, B

doi:10.1016/s0040-4039(00)01173-4

Reaction of 4-methoxy-4-(1-methylethenyl)-2-cyclobutenone derivatives with 2-lithiopropene and alpha-lithiostyrene: synthesis of eight-membered ring carbocycles

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Zora M., Koyuncu I., Yucel B.

TETRAHEDRON LETTERS, vol.41, no.36, pp.7111-7114, 2000 (SCI-Expanded)

Publication Type: Article / Article
Volume: 41 Issue: 36
Publication Date: 2000
Doi Number: 10.1016/s0040-4039(00)01173-4
Journal Name: TETRAHEDRON LETTERS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.7111-7114
Middle East Technical University Affiliated: Yes

Abstract

2-Alkyl- or phenyl-substituted 4-methoxy-4-(1-methylethenyl)-2-cyclobutenones react with 2-lithiopropene or alpha-lithiostyrene to produce 4-methoxy-2,4-cyclooctadienones in moderate yield, accompanied by varying amounts of 4-methoxy-4-(1-methylethenyl)-2-cyclohexenones. The reaction is general for 2-alkyl substituted 4-methoxy-4-(1-methylethenyl)-2-cyclobutenones. (C) 2000 Elsevier Science Ltd. All rights reserved.